DE69230418D1 - GRF-Analoge (Growth Hormone Releasing Factors) - Google Patents

GRF-Analoge (Growth Hormone Releasing Factors)

Info

Publication number
DE69230418D1
DE69230418D1 DE69230418T DE69230418T DE69230418D1 DE 69230418 D1 DE69230418 D1 DE 69230418D1 DE 69230418 T DE69230418 T DE 69230418T DE 69230418 T DE69230418 T DE 69230418T DE 69230418 D1 DE69230418 D1 DE 69230418D1
Authority
DE
Germany
Prior art keywords
ala
aib
leu
tyr
phe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69230418T
Other languages
English (en)
Inventor
Jean Edouard Frederic Rivier
Wylie Walker Vale
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Application granted granted Critical
Publication of DE69230418D1 publication Critical patent/DE69230418D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
DE69230418T 1991-05-15 1992-05-15 GRF-Analoge (Growth Hormone Releasing Factors) Expired - Lifetime DE69230418D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/701,414 US5262519A (en) 1991-05-15 1991-05-15 GRF analogs XI

Publications (1)

Publication Number Publication Date
DE69230418D1 true DE69230418D1 (de) 2000-01-20

Family

ID=24817283

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69230418T Expired - Lifetime DE69230418D1 (de) 1991-05-15 1992-05-15 GRF-Analoge (Growth Hormone Releasing Factors)

Country Status (13)

Country Link
US (1) US5262519A (de)
EP (1) EP0514210B1 (de)
JP (1) JPH06500575A (de)
KR (1) KR100236413B1 (de)
AT (1) ATE187741T1 (de)
AU (1) AU654195B2 (de)
CA (1) CA2086676A1 (de)
DE (1) DE69230418D1 (de)
FI (1) FI930152A0 (de)
IL (1) IL101764A (de)
NZ (1) NZ242610A (de)
WO (1) WO1992020710A1 (de)
ZA (1) ZA923281B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06502618A (ja) * 1990-05-04 1994-03-24 ジ・アドミニストレイターズ・オブ・ザ・テュレイン・エデュケイショナル・ファンド 新規な合成ｇｒｆ類似物
CA2158782C (en) * 1994-09-23 2010-01-12 Pierrette Gaudreau Marker for growth hormone-releasing factor receptors
AU5441096A (en) * 1995-04-14 1996-10-30 The Administrators Of The Tulane Eductional Fund Analogs of growth hormone-releasing factor
MXPA05002991A (es) * 2002-09-18 2005-10-05 Univ Montreal Ct Hospitalier Chum Analogos de ghrh.
PT2118123E (pt) 2007-01-31 2016-02-10 Harvard College Péptidos de p53 estabilizados e suas utilizações
WO2008121767A2 (en) 2007-03-28 2008-10-09 President And Fellows Of Harvard College Stitched polypeptides
WO2009009727A2 (en) * 2007-07-12 2009-01-15 Akela Pharma Srl Ghrh analogs and therapeutic uses thereof
US8980249B2 (en) 2010-06-03 2015-03-17 University Of Miami Agonists of growth hormone releasing hormone as effectors for survival and proliferation of pancreatic islets
RU2582678C2 (ru) 2010-08-13 2016-04-27 Эйлерон Терапьютикс, Инк. Пептидомиметические макроциклы
WO2012142706A1 (en) 2011-04-21 2012-10-26 Theratechnologies Inc. Growth hormone releasing factor (grf) analogs and uses thereof
TWI643868B (zh) 2011-10-18 2018-12-11 艾利倫治療公司 擬肽巨環化合物
US9079974B2 (en) 2011-12-21 2015-07-14 The University Of Miami GH-RH analogs with potent agonistic effects
JP6450191B2 (ja) 2012-02-15 2019-01-09 エイルロン セラピューティクス，インコーポレイテッド ペプチドミメティック大環状化合物
EP2819688A4 (de) 2012-02-15 2015-10-28 Aileron Therapeutics Inc Triazol- und thioethervernetzte peptidomimetische makrozyklen
WO2014071241A1 (en) 2012-11-01 2014-05-08 Aileron Therapeutics, Inc. Disubstituted amino acids and methods of preparation and use thereof
WO2014100816A2 (en) 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for islet cell transplantation and function and the treatment of diabetes
WO2014100809A2 (en) * 2012-12-21 2014-06-26 University Of Miami Ghrh agonists for the treatment of ischemic disorders
KR20170058424A (ko) 2014-09-24 2017-05-26 에일러론 테라퓨틱스 인코포레이티드 펩티드모방 거대고리 및 이의 용도
JP2018516844A (ja) 2015-03-20 2018-06-28 エルロン・セラピューティクス・インコーポレイテッドＡｉｌｅｒｏｎ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． ペプチド模倣大環状分子およびその使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649131A (en) * 1984-09-24 1987-03-10 Hoffmann-La Roche Inc. Growth hormone releasing factor analogs
US4689318A (en) * 1985-08-29 1987-08-25 The Salk Institute For Biological Studies GRF analogs
US4746772A (en) * 1986-09-23 1988-05-24 Fisher Controls International, Inc. Adjustable position indicating apparatus
US4843064A (en) * 1987-01-13 1989-06-27 The Salk Institute For Biological Studies GRF analogs V
US5002931A (en) * 1987-05-22 1991-03-26 The Salk Institute For Biological Studies GRF analogs VII
US5098995A (en) * 1987-05-22 1992-03-24 The Salk Institute For Biological Studies GRF Analogs VIIA
US5043322A (en) * 1988-07-22 1991-08-27 The Salk Institute For Biological Studies Cyclic GRF analogs
JPH06502618A (ja) * 1990-05-04 1994-03-24 ジ・アドミニストレイターズ・オブ・ザ・テュレイン・エデュケイショナル・ファンド 新規な合成ｇｒｆ類似物

Also Published As

Publication number Publication date
AU1996392A (en) 1992-12-30
IL101764A0 (en) 1992-12-30
IL101764A (en) 1996-07-23
ATE187741T1 (de) 2000-01-15
US5262519A (en) 1993-11-16
AU654195B2 (en) 1994-10-27
EP0514210B1 (de) 1999-12-15
EP0514210A3 (en) 1993-04-28
FI930152A (fi) 1993-01-14
KR100236413B1 (ko) 1999-12-15
ZA923281B (en) 1993-01-27
WO1992020710A1 (en) 1992-11-26
FI930152A0 (fi) 1993-01-14
JPH06500575A (ja) 1994-01-20
EP0514210A2 (de) 1992-11-19
NZ242610A (en) 1993-11-25
KR930701483A (ko) 1993-06-11
CA2086676A1 (en) 1992-11-16

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