DE69230415T2 - Cephalosporinverbindungen und ihre pharmazeutische Präparate - Google Patents

Cephalosporinverbindungen und ihre pharmazeutische Präparate

Info

Publication number
DE69230415T2
DE69230415T2 DE69230415T DE69230415T DE69230415T2 DE 69230415 T2 DE69230415 T2 DE 69230415T2 DE 69230415 T DE69230415 T DE 69230415T DE 69230415 T DE69230415 T DE 69230415T DE 69230415 T2 DE69230415 T2 DE 69230415T2
Authority
DE
Germany
Prior art keywords
alkyl
pharmaceutical preparations
hydrogen
cephalosporin compounds
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69230415T
Other languages
English (en)
Other versions
DE69230415D1 (de
Inventor
Robert John Ternansky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of DE69230415D1 publication Critical patent/DE69230415D1/de
Application granted granted Critical
Publication of DE69230415T2 publication Critical patent/DE69230415T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
DE69230415T 1991-01-18 1992-01-09 Cephalosporinverbindungen und ihre pharmazeutische Präparate Expired - Fee Related DE69230415T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US64295991A 1991-01-18 1991-01-18

Publications (2)

Publication Number Publication Date
DE69230415D1 DE69230415D1 (de) 2000-01-20
DE69230415T2 true DE69230415T2 (de) 2000-05-11

Family

ID=24578768

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69230415T Expired - Fee Related DE69230415T2 (de) 1991-01-18 1992-01-09 Cephalosporinverbindungen und ihre pharmazeutische Präparate

Country Status (23)

Country Link
US (1) US5362722A (de)
EP (1) EP0495584B1 (de)
JP (1) JP3164390B2 (de)
KR (1) KR920014818A (de)
CN (1) CN1063286A (de)
AT (1) ATE187729T1 (de)
AU (1) AU642333B2 (de)
BR (1) BR9200057A (de)
CA (1) CA2058822C (de)
CZ (1) CZ281684B6 (de)
DE (1) DE69230415T2 (de)
ES (1) ES2141096T3 (de)
FI (1) FI920111A (de)
HU (1) HUT60276A (de)
IE (1) IE920085A1 (de)
IL (1) IL100576A (de)
MX (1) MX9200102A (de)
NO (1) NO301330B1 (de)
NZ (1) NZ241249A (de)
PT (1) PT99983B (de)
RU (1) RU2104280C1 (de)
YU (1) YU2292A (de)
ZA (1) ZA9224B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077287A (en) * 1991-01-18 1991-12-31 Eli Lilly And Company 3-thiazolylthio carbacephem antibacterial agents
JPH05132488A (ja) * 1991-08-13 1993-05-28 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体
JP2857532B2 (ja) * 1992-03-12 1999-02-17 明治製菓株式会社 新規セファロスポリン誘導体
US5525599A (en) * 1993-07-21 1996-06-11 Eli Lilly And Company 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
TWI288745B (en) 2000-04-05 2007-10-21 Daiichi Seiyaku Co Ethylenediamine derivatives
PL214669B1 (pl) 2001-06-20 2013-08-30 Daiichi Sankyo Company Pochodne diaminy, kompozycja je zawierajaca oraz ich zastosowanie
WO2003000657A1 (fr) 2001-06-20 2003-01-03 Daiichi Pharmaceutical Co., Ltd. Derives de diamine

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5214789A (en) * 1975-07-22 1977-02-03 Shionogi & Co Ltd Process for preparing 3-substiuted cephem compounds by ring closure
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
EP0009008A3 (de) * 1978-09-08 1980-05-14 Ciba-Geigy Ag Cephalosporinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
US4500526A (en) * 1982-06-28 1985-02-19 Bristol-Myers Company Cephalosporin derivatives
GB8410992D0 (en) * 1984-04-30 1984-06-06 Glaxo Group Ltd Process
JPH0653739B2 (ja) * 1984-11-15 1994-07-20 協和醗酵工業株式会社 ３位置換カルバセフエム化合物
GB2177691A (en) * 1985-07-18 1987-01-28 Glaxo Group Ltd Cephalosporin antibiotics
US5142039A (en) * 1987-07-31 1992-08-25 Eli Lilly And Company β-lactam antibiotics
JP2568248B2 (ja) * 1988-04-22 1996-12-25 第一製薬株式会社 ３−セフェム−４−カルボン酸
JPH0686459B2 (ja) * 1989-12-07 1994-11-02 明治製菓株式会社 ３―置換チオ―３―セフエム化合物の製造法
EP0432042B1 (de) * 1989-12-07 1996-08-28 Meiji Seika Kaisha Ltd. Cephalosporinderivate, ihre Herstellung und Anwendungen
IE65926B1 (en) * 1990-07-19 1995-11-29 Shionogi & Co Thioalkylthio cephalosporin derivatives
US5077287A (en) * 1991-01-18 1991-12-31 Eli Lilly And Company 3-thiazolylthio carbacephem antibacterial agents
US5247073A (en) * 1991-01-18 1993-09-21 Eli Lilly And Company 7-(Amino or protected amino)-3-thioheterobicyclic cephalosporins
JPH05132488A (ja) * 1991-08-13 1993-05-28 Meiji Seika Kaisha Ltd 新規セフアロスポリン誘導体
JPH09109037A (ja) * 1995-10-23 1997-04-28 Denso Corp スライド機能付き締付け装置

Also Published As

Publication number Publication date
EP0495584A2 (de) 1992-07-22
ES2141096T3 (es) 2000-03-16
JP3164390B2 (ja) 2001-05-08
NO301330B1 (no) 1997-10-13
HUT60276A (en) 1992-08-28
CA2058822A1 (en) 1992-07-19
IL100576A0 (en) 1992-09-06
FI920111A0 (fi) 1992-01-10
JPH04321691A (ja) 1992-11-11
PT99983A (pt) 1993-01-29
NZ241249A (en) 1993-04-28
RU2104280C1 (ru) 1998-02-10
YU2292A (sh) 1994-11-15
CZ281684B6 (cs) 1996-12-11
FI920111A (fi) 1992-07-19
ATE187729T1 (de) 2000-01-15
CS1292A3 (en) 1992-08-12
CN1063286A (zh) 1992-08-05
HU9200082D0 (en) 1992-03-30
DE69230415D1 (de) 2000-01-20
AU642333B2 (en) 1993-10-14
BR9200057A (pt) 1992-09-08
PT99983B (pt) 1999-06-30
IL100576A (en) 1995-11-27
NO920102D0 (no) 1992-01-08
ZA9224B (en) 1993-07-02
CA2058822C (en) 2000-06-27
EP0495584A3 (en) 1992-11-04
EP0495584B1 (de) 1999-12-15
AU1013492A (en) 1992-07-23
US5362722A (en) 1994-11-08
NO920102L (no) 1992-07-20
KR920014818A (ko) 1992-08-25
MX9200102A (es) 1992-07-01
IE920085A1 (en) 1992-07-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee