DE69230135T2 - Dna-sequenz, die für rinder-g(a)-lactalbumin kodiert, und nutzungsmethoden - Google Patents

Dna-sequenz, die für rinder-g(a)-lactalbumin kodiert, und nutzungsmethoden

Info

Publication number
DE69230135T2
DE69230135T2 DE69230135T DE69230135T DE69230135T2 DE 69230135 T2 DE69230135 T2 DE 69230135T2 DE 69230135 T DE69230135 T DE 69230135T DE 69230135 T DE69230135 T DE 69230135T DE 69230135 T2 DE69230135 T2 DE 69230135T2
Authority
DE
Germany
Prior art keywords
dna sequence
lactalbumine
methods
milk
sequence encoding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69230135T
Other languages
English (en)
Other versions
DE69230135D1 (de
Inventor
Gregory Bleck
Robert Bremel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wisconsin Milk Marketing Board Inc
Original Assignee
Wisconsin Milk Marketing Board Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Milk Marketing Board Inc filed Critical Wisconsin Milk Marketing Board Inc
Application granted granted Critical
Publication of DE69230135D1 publication Critical patent/DE69230135D1/de
Publication of DE69230135T2 publication Critical patent/DE69230135T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
DE69230135T 1991-08-13 1992-08-06 Dna-sequenz, die für rinder-g(a)-lactalbumin kodiert, und nutzungsmethoden Expired - Lifetime DE69230135T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74476591A 1991-08-13 1991-08-13
PCT/US1992/006549 WO1993004165A1 (en) 1991-08-13 1992-08-06 DNA SEQUENCE ENCODING BOVINE α-LACTALBUMIN AND METHODS OF USE

Publications (2)

Publication Number Publication Date
DE69230135D1 DE69230135D1 (de) 1999-11-18
DE69230135T2 true DE69230135T2 (de) 2000-06-21

Family

ID=24993913

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69230135T Expired - Lifetime DE69230135T2 (de) 1991-08-13 1992-08-06 Dna-sequenz, die für rinder-g(a)-lactalbumin kodiert, und nutzungsmethoden

Country Status (11)

Country Link
US (2) US5530177A (de)
EP (1) EP0555435B1 (de)
JP (1) JP3698369B2 (de)
AT (1) ATE185596T1 (de)
AU (1) AU663101B2 (de)
CA (1) CA2093659C (de)
DE (1) DE69230135T2 (de)
DK (1) DK0555435T3 (de)
IL (1) IL102783A0 (de)
NZ (1) NZ243930A (de)
WO (1) WO1993004165A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5633076A (en) * 1989-12-01 1997-05-27 Pharming Bv Method of producing a transgenic bovine or transgenic bovine embryo
US5374523A (en) * 1992-08-10 1994-12-20 Monsanto Company Allelic variants of bovine somatotropin gene:genetic marker for superior milk production in bovine
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
WO1995018224A1 (en) * 1993-12-29 1995-07-06 Gene Pharming Europe Bv Recombinant production of modified proteins lacking certain amino acids
GB9425326D0 (en) * 1994-12-15 1995-02-15 Ppl Therapeutics Scotland Ltd Gene constructs
US5780009A (en) * 1995-01-20 1998-07-14 Nexia Biotechnologies, Inc. Direct gene transfer into the ruminant mammary gland
US5907080A (en) * 1995-11-30 1999-05-25 Nexia Biotechnologies, Inc. Method for development of transgenic dwarf goats
EP1007628B1 (de) 1996-09-26 2006-03-15 The Regents of the University of Colorado Transgenes modell für herzversagen
US5968809A (en) * 1997-04-11 1999-10-19 Abbot Laboratories Methods and compositions for synthesis of long chain poly-unsaturated fatty acids
DE69823206T2 (de) * 1997-07-25 2004-08-19 Affymetrix, Inc. (a Delaware Corp.), Santa Clara Verfahren zur herstellung einer bio-informatik-datenbank
WO1999009816A1 (de) * 1997-08-22 1999-03-04 Roche Diagnostics Gmbh Verfahren zur gewinnung von insulin precursorproteinen
GB9718908D0 (en) * 1997-09-05 1997-11-12 Rowett Research Services Limit Proteins
KR20010031210A (ko) * 1997-10-20 2001-04-16 추후보정 세포계내의 ｍＲＮＡ량 및 단백질 발현을 증가시키는 방법및 변형 핵산 서열
US20020106729A1 (en) * 2000-07-03 2002-08-08 Bleck Gregory T. Expression vectors
US20040235173A1 (en) * 2000-07-03 2004-11-25 Gala Design, Inc. Production of host cells containing multiple integrating vectors by serial transduction
US20030224415A1 (en) * 2001-06-29 2003-12-04 Gala Design, Inc. Selection free growth of host cells containing multiple integrating vectors
KR100868594B1 (ko) * 2000-07-03 2008-11-13 갈라 디자인, 인크. 다수의 통합 벡터를 함유하는 숙주 세포
US6852510B2 (en) * 2000-07-03 2005-02-08 Gala Design Inc Host cells containing multiple integrating vectors
AU2001284948A1 (en) * 2000-08-15 2002-02-25 Board Of Trustees Of The University Of Illinois Animals expressing exogenous igf-i in their milk
JP4360915B2 (ja) 2002-01-07 2009-11-11 ユーロスクリーン・ソシエテ・アノニム Ｇタンパク質共役受容体ｇｐｒ４３のリガンドおよびその使用
US7384738B2 (en) * 2002-03-28 2008-06-10 Bremel Robert D Retrovirus-based genomic screening
US20040038304A1 (en) * 2002-03-28 2004-02-26 Gala Design, Inc. Antibody libraries
GB0314856D0 (en) 2003-06-25 2003-07-30 Unitargeting Res As Protein expression system
US20050221429A1 (en) * 2004-01-16 2005-10-06 Cardinal Health Pts, Llc Host cells containing multiple integrating vectors comprising an amplifiable marker
JP2007524693A (ja) 2004-02-20 2007-08-30 ザ バーナム インスティチュート 抗菌性の糖質及びそれを用いた方法
JP2006168685A (ja) * 2004-12-20 2006-06-29 Yamaha Marine Co Ltd 船外機

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988001648A1 (en) * 1986-08-28 1988-03-10 Immunex Corporation Expression of heterologous proteins by transgenic lactating mammals
DE69027683T2 (de) * 1989-12-01 1997-02-13 Pharming Bv Herstellung rekombinanter polypeptide durch rinder und transgene methoden

Also Published As

Publication number Publication date
EP0555435A4 (de) 1995-05-24
US5530177A (en) 1996-06-25
JPH06502550A (ja) 1994-03-24
EP0555435A1 (de) 1993-08-18
AU663101B2 (en) 1995-09-28
AU2411992A (en) 1993-03-16
IL102783A0 (en) 1993-01-31
WO1993004165A1 (en) 1993-03-04
EP0555435B1 (de) 1999-10-13
CA2093659A1 (en) 1993-02-14
DK0555435T3 (da) 2000-04-25
DE69230135D1 (de) 1999-11-18
CA2093659C (en) 2001-01-16
NZ243930A (en) 1995-02-24
JP3698369B2 (ja) 2005-09-21
ATE185596T1 (de) 1999-10-15
US5850000A (en) 1998-12-15

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