DE69227395T2 - Heparitinase, Verfahren zur Herstellung und Bakterie, die Heparitinase herstellt - Google Patents

Heparitinase, Verfahren zur Herstellung und Bakterie, die Heparitinase herstellt

Info

Publication number
DE69227395T2
DE69227395T2 DE69227395T DE69227395T DE69227395T2 DE 69227395 T2 DE69227395 T2 DE 69227395T2 DE 69227395 T DE69227395 T DE 69227395T DE 69227395 T DE69227395 T DE 69227395T DE 69227395 T2 DE69227395 T2 DE 69227395T2
Authority
DE
Germany
Prior art keywords
heparitinase
manufacturing process
bacteria producing
bacteria
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69227395T
Other languages
English (en)
Other versions
DE69227395D1 (de
Inventor
Kiyoshi Morikawa
Hirofumi Miyazono
Hiroshi Maruyama
Keiichi Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Publication of DE69227395D1 publication Critical patent/DE69227395D1/de
Application granted granted Critical
Publication of DE69227395T2 publication Critical patent/DE69227395T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/07—Bacillus
    • C12R2001/09—Bacillus circulans
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/835—Bacillus circulans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69227395T 1991-03-06 1992-03-04 Heparitinase, Verfahren zur Herstellung und Bakterie, die Heparitinase herstellt Expired - Fee Related DE69227395T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP03063707A JP3110064B2 (ja) 1991-03-06 1991-03-06 新規ヘパリチナーゼ、その製造法及びその生産菌

Publications (2)

Publication Number Publication Date
DE69227395D1 DE69227395D1 (de) 1998-12-03
DE69227395T2 true DE69227395T2 (de) 1999-04-22

Family

ID=13237119

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69227395T Expired - Fee Related DE69227395T2 (de) 1991-03-06 1992-03-04 Heparitinase, Verfahren zur Herstellung und Bakterie, die Heparitinase herstellt

Country Status (5)

Country Link
US (2) US5290695A (de)
EP (1) EP0502496B1 (de)
JP (1) JP3110064B2 (de)
DE (1) DE69227395T2 (de)
DK (1) DK0502496T3 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
EP0798376B1 (de) * 1994-11-22 2004-02-18 Seikagaku Corporation Neuartige keratansulfat-hydrolase
CA2235223A1 (en) 1995-10-30 1997-05-09 Massachusetts Institute Of Technology Rationally designed polysaccharide lyases derived from heparinase i
US5968806A (en) * 1997-05-22 1999-10-19 Seikagaku Corporation Bacillus circulans KsT202 produces keratan sulfate hydrolase
US7056504B1 (en) 1998-08-27 2006-06-06 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase I and II
WO2000012726A2 (en) * 1998-08-27 2000-03-09 Massachusetts Institute Of Technology Rationally designed heparinases derived from heparinase i and ii
US6597996B1 (en) * 1999-04-23 2003-07-22 Massachusetts Institute Of Technology Method for indentifying or characterizing properties of polymeric units
ES2527853T3 (es) * 2000-03-08 2015-01-30 Massachusetts Institute Of Technology Heparinasa III y sus usos
JP2002017371A (ja) * 2000-07-07 2002-01-22 Seikagaku Kogyo Co Ltd ヘパリチナーゼｔ−ｉｖのポリペプチド及びそれをコードするｄｎａ
EP1319183B1 (de) * 2000-09-12 2009-03-25 Massachusetts Institute Of Technology Verfahren und produkte, die mit niedermolekularem heparin assoziiert sind
EP1328260A2 (de) * 2000-10-18 2003-07-23 Massachusetts Institute Of Technology Verfahren und produkte zur pulmonalen verabreichung von polysacchariden
EP1532241B1 (de) * 2002-06-03 2010-09-15 Massachusetts Institute Of Technology Rationell konstruierte, von chondroitinase b abgeleitete lyasen
WO2006023487A2 (en) * 2004-08-16 2006-03-02 Massachusetts Institute Of Technology Rapid two-step synthesis of anti-coagulants
US7772668B2 (en) * 2007-12-26 2010-08-10 Fairchild Semiconductor Corporation Shielded gate trench FET with multiple channels

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2697824B2 (ja) * 1987-07-28 1998-01-14 キヤノン株式会社 文書画像処理装置における制御方法
JPH01132381A (ja) * 1987-11-19 1989-05-24 Kyodo Nyugyo Kk ヘパリチナーゼ及びその製造法
JP2801608B2 (ja) * 1988-08-24 1998-09-21 生化学工業株式会社 新規ヘパラン硫酸分解酵素並びにそれを生産する微生物及び方法
JPH0693836B2 (ja) * 1988-11-25 1994-11-24 新技術事業団 バチルス属に属するヘパリナーゼ生産微生物、新規ヘパリナーゼ及びその製法
JP2815449B2 (ja) * 1990-02-23 1998-10-27 科学技術振興事業団 低分子量へパリンの製造方法

Also Published As

Publication number Publication date
DE69227395D1 (de) 1998-12-03
EP0502496A3 (en) 1992-10-07
US5290695A (en) 1994-03-01
JPH04278087A (ja) 1992-10-02
EP0502496B1 (de) 1998-10-28
US5405759A (en) 1995-04-11
EP0502496A2 (de) 1992-09-09
JP3110064B2 (ja) 2000-11-20
DK0502496T3 (da) 1999-07-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee