DE69220565T2 - Verfahren zur Herstellung von 2-Amino-6-chloropurin und Derivaten - Google Patents

Verfahren zur Herstellung von 2-Amino-6-chloropurin und Derivaten

Info

Publication number
DE69220565T2
DE69220565T2 DE69220565T DE69220565T DE69220565T2 DE 69220565 T2 DE69220565 T2 DE 69220565T2 DE 69220565 T DE69220565 T DE 69220565T DE 69220565 T DE69220565 T DE 69220565T DE 69220565 T2 DE69220565 T2 DE 69220565T2
Authority
DE
Germany
Prior art keywords
chloropurine
amino
derivatives
preparation
diacylguanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69220565T
Other languages
English (en)
Other versions
DE69220565D1 (de
Inventor
John Christopher Smithk Hanson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis International Pharmaceutical Ltd
Original Assignee
SmithKline Beecham Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Ltd filed Critical SmithKline Beecham Ltd
Application granted granted Critical
Publication of DE69220565D1 publication Critical patent/DE69220565D1/de
Publication of DE69220565T2 publication Critical patent/DE69220565T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/40Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69220565T 1991-01-31 1992-01-30 Verfahren zur Herstellung von 2-Amino-6-chloropurin und Derivaten Expired - Lifetime DE69220565T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB919102127A GB9102127D0 (en) 1991-01-31 1991-01-31 Pharmaceuticals
PCT/GB1992/000177 WO1992013859A1 (en) 1991-01-31 1992-01-30 Pharmaceuticals

Publications (2)

Publication Number Publication Date
DE69220565D1 DE69220565D1 (de) 1997-07-31
DE69220565T2 true DE69220565T2 (de) 1997-12-11

Family

ID=10689331

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69220565T Expired - Lifetime DE69220565T2 (de) 1991-01-31 1992-01-30 Verfahren zur Herstellung von 2-Amino-6-chloropurin und Derivaten

Country Status (19)

Country Link
US (2) US5910589A (de)
EP (1) EP0569421B1 (de)
JP (1) JP2618578B2 (de)
KR (1) KR100213936B1 (de)
AT (1) ATE154803T1 (de)
AU (1) AU655002B2 (de)
CA (1) CA2101640C (de)
DE (1) DE69220565T2 (de)
DK (1) DK0569421T3 (de)
ES (1) ES2104892T3 (de)
GB (1) GB9102127D0 (de)
GR (1) GR3023917T3 (de)
HK (1) HK1007312A1 (de)
IE (1) IE920294A1 (de)
MX (1) MX9200398A (de)
NZ (1) NZ241442A (de)
PT (1) PT100074B (de)
WO (1) WO1992013859A1 (de)
ZA (1) ZA92606B (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor
GB9201961D0 (en) * 1992-01-30 1992-03-18 Smithkline Beecham Plc Pharmaceuticals
DE4231036A1 (de) * 1992-09-17 1994-03-24 Basf Ag Verfahren zur Herstellung von 2-Amino-6-halogenpurinen
JPH07133276A (ja) * 1993-09-17 1995-05-23 Jiyuuzen Kagaku Kk 2−アセチルアミノ−6−クロロプリンの製造方法
WO1996021664A1 (de) * 1995-01-09 1996-07-18 Lonza Ag Verfahren zur herstellung von 2-amino-6-chlorpurin und zwischenprodukte dafür
US5789590A (en) * 1995-11-09 1998-08-04 Sumika Fine Chemicals Co., Ltd. Double cone-like crystal form of 2-amino-6-chloropurine and preparation
US6419934B1 (en) 1999-02-24 2002-07-16 Edward L. Tobinick TNF modulators for treating neurological disorders associated with viral infection
RU2280645C2 (ru) * 2001-04-05 2006-07-27 Сумитомо Кемикал Компани, Лимитед Способ получения 2,6-дигалогенпурина
US20100136106A1 (en) * 2005-06-08 2010-06-03 Gary Liversidge Modified Release Famciclovir Compositions
EP1852435A1 (de) * 2006-04-12 2007-11-07 SOLMAG S.p.A. Verfahren zur Herstellung von Famciclovir mittels Phasenübertragungskatalysatoren

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3485225D1 (de) * 1983-08-18 1991-12-05 Beecham Group Plc Antivirale guanin-derivate.
EP0182024B1 (de) * 1984-09-20 1991-04-03 Beecham Group Plc Purin-Derivate und ihre pharmazeutische Verwendung
GB8507606D0 (en) * 1985-03-23 1985-05-01 Beecham Group Plc Process
GB8916698D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Novel process
DE3941657A1 (de) * 1989-12-16 1991-06-20 Hoechst Ag Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin
GB9102127D0 (en) * 1991-01-31 1991-03-13 Smithkline Beecham Plc Pharmaceuticals
CA2076886C (en) * 1991-11-22 2002-06-11 Masami Igi Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor

Also Published As

Publication number Publication date
ZA92606B (en) 1992-12-30
GB9102127D0 (en) 1991-03-13
EP0569421A1 (de) 1993-11-18
EP0569421B1 (de) 1997-06-25
ATE154803T1 (de) 1997-07-15
US5910589A (en) 1999-06-08
AU1185892A (en) 1992-09-07
HK1007312A1 (en) 1999-04-09
NZ241442A (en) 1994-11-25
KR100213936B1 (ko) 1999-08-02
WO1992013859A1 (en) 1992-08-20
ES2104892T3 (es) 1997-10-16
MX9200398A (es) 1992-07-01
GR3023917T3 (en) 1997-09-30
CA2101640A1 (en) 1992-08-01
CA2101640C (en) 2002-07-09
KR930703320A (ko) 1993-11-29
DK0569421T3 (da) 1997-09-01
JP2618578B2 (ja) 1997-06-11
PT100074B (pt) 1999-06-30
DE69220565D1 (de) 1997-07-31
US6093819A (en) 2000-07-25
AU655002B2 (en) 1994-12-01
JPH06504995A (ja) 1994-06-09
IE920294A1 (en) 1992-07-29
PT100074A (pt) 1993-06-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD., HAMILT