ES2104892T3 - Procedimiento para la preparacion de 2-amino-6-cloropurina y sus derivados. - Google Patents
Procedimiento para la preparacion de 2-amino-6-cloropurina y sus derivados.Info
- Publication number
- ES2104892T3 ES2104892T3 ES92903581T ES92903581T ES2104892T3 ES 2104892 T3 ES2104892 T3 ES 2104892T3 ES 92903581 T ES92903581 T ES 92903581T ES 92903581 T ES92903581 T ES 92903581T ES 2104892 T3 ES2104892 T3 ES 2104892T3
- Authority
- ES
- Spain
- Prior art keywords
- chloropurine
- amino
- derivatives
- procedure
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE PRESENTA UN PROCESO PARA PREPARAR 2-AMINO-6-CLOROPURINA O UN DERIVADO 2-ACILADO DE LA MISMA, EL PROCESO COMPRENDE LA REACCION DE GUANINA O 2,9-DIACILGUANINA CON UN AGENTE CLORADOR, EN LA PRESENCIA DE CLORURO DE METILTRIETILAMONIO COMO CATALIZADOR DE TRANSFERENCIA DE FASE, Y POSTERIORMENTE, CUANDO SEA NECESARIO, LA SEPARACION DEL GRUPO 9-ACIL MEDIANTE HIDROLISIS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919102127A GB9102127D0 (en) | 1991-01-31 | 1991-01-31 | Pharmaceuticals |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2104892T3 true ES2104892T3 (es) | 1997-10-16 |
Family
ID=10689331
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92903581T Expired - Lifetime ES2104892T3 (es) | 1991-01-31 | 1992-01-30 | Procedimiento para la preparacion de 2-amino-6-cloropurina y sus derivados. |
Country Status (19)
Country | Link |
---|---|
US (2) | US5910589A (es) |
EP (1) | EP0569421B1 (es) |
JP (1) | JP2618578B2 (es) |
KR (1) | KR100213936B1 (es) |
AT (1) | ATE154803T1 (es) |
AU (1) | AU655002B2 (es) |
CA (1) | CA2101640C (es) |
DE (1) | DE69220565T2 (es) |
DK (1) | DK0569421T3 (es) |
ES (1) | ES2104892T3 (es) |
GB (1) | GB9102127D0 (es) |
GR (1) | GR3023917T3 (es) |
HK (1) | HK1007312A1 (es) |
IE (1) | IE920294A1 (es) |
MX (1) | MX9200398A (es) |
NZ (1) | NZ241442A (es) |
PT (1) | PT100074B (es) |
WO (1) | WO1992013859A1 (es) |
ZA (1) | ZA92606B (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9102127D0 (en) * | 1991-01-31 | 1991-03-13 | Smithkline Beecham Plc | Pharmaceuticals |
CA2076886C (en) * | 1991-11-22 | 2002-06-11 | Masami Igi | Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor |
GB9201961D0 (en) * | 1992-01-30 | 1992-03-18 | Smithkline Beecham Plc | Pharmaceuticals |
DE4231036A1 (de) * | 1992-09-17 | 1994-03-24 | Basf Ag | Verfahren zur Herstellung von 2-Amino-6-halogenpurinen |
JPH07133276A (ja) * | 1993-09-17 | 1995-05-23 | Jiyuuzen Kagaku Kk | 2−アセチルアミノ−6−クロロプリンの製造方法 |
WO1996021664A1 (de) * | 1995-01-09 | 1996-07-18 | Lonza Ag | Verfahren zur herstellung von 2-amino-6-chlorpurin und zwischenprodukte dafür |
CA2189088C (en) * | 1995-11-09 | 2005-09-20 | Masatoshi Sakai | 2-amino-6-chloropurine and method for preparing the same |
US6419934B1 (en) | 1999-02-24 | 2002-07-16 | Edward L. Tobinick | TNF modulators for treating neurological disorders associated with viral infection |
ATE364607T1 (de) * | 2001-04-05 | 2007-07-15 | Sumitomo Chemical Co | Verfahren zur produktion von 2,6- dihalogenopurinen |
WO2007037790A2 (en) * | 2005-06-08 | 2007-04-05 | Elan Corporation, Plc | Modified release famciclovir compositions |
EP1852435A1 (en) * | 2006-04-12 | 2007-11-07 | SOLMAG S.p.A. | A process for the manufacture of famciclovir using phase-transfer catalysts |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3485225D1 (de) * | 1983-08-18 | 1991-12-05 | Beecham Group Plc | Antivirale guanin-derivate. |
DE3582399D1 (de) * | 1984-09-20 | 1991-05-08 | Beecham Group Plc | Purin-derivate und ihre pharmazeutische verwendung. |
GB8507606D0 (en) * | 1985-03-23 | 1985-05-01 | Beecham Group Plc | Process |
GB8916698D0 (en) * | 1989-07-21 | 1989-09-06 | Beecham Group Plc | Novel process |
DE3941657A1 (de) * | 1989-12-16 | 1991-06-20 | Hoechst Ag | Verfahren zur herstellung von 2-acylamino-6-halogen-purin aus 2,9-diacylguanin |
GB9102127D0 (en) * | 1991-01-31 | 1991-03-13 | Smithkline Beecham Plc | Pharmaceuticals |
CA2076886C (en) * | 1991-11-22 | 2002-06-11 | Masami Igi | Method for production of 2-amino-6-halogenopurine and synthesis intermediate therefor |
-
1991
- 1991-01-31 GB GB919102127A patent/GB9102127D0/en active Pending
-
1992
- 1992-01-29 ZA ZA92606A patent/ZA92606B/xx unknown
- 1992-01-29 NZ NZ241442A patent/NZ241442A/en not_active IP Right Cessation
- 1992-01-29 IE IE029492A patent/IE920294A1/en not_active IP Right Cessation
- 1992-01-30 CA CA002101640A patent/CA2101640C/en not_active Expired - Lifetime
- 1992-01-30 DE DE69220565T patent/DE69220565T2/de not_active Expired - Lifetime
- 1992-01-30 KR KR1019930702265A patent/KR100213936B1/ko not_active IP Right Cessation
- 1992-01-30 EP EP92903581A patent/EP0569421B1/en not_active Expired - Lifetime
- 1992-01-30 DK DK92903581.4T patent/DK0569421T3/da active
- 1992-01-30 AU AU11858/92A patent/AU655002B2/en not_active Ceased
- 1992-01-30 AT AT92903581T patent/ATE154803T1/de not_active IP Right Cessation
- 1992-01-30 WO PCT/GB1992/000177 patent/WO1992013859A1/en active IP Right Grant
- 1992-01-30 US US08/409,490 patent/US5910589A/en not_active Expired - Lifetime
- 1992-01-30 MX MX9200398A patent/MX9200398A/es unknown
- 1992-01-30 JP JP4503581A patent/JP2618578B2/ja not_active Expired - Fee Related
- 1992-01-30 PT PT100074A patent/PT100074B/pt not_active IP Right Cessation
- 1992-01-30 ES ES92903581T patent/ES2104892T3/es not_active Expired - Lifetime
-
1997
- 1997-06-26 GR GR970401565T patent/GR3023917T3/el unknown
-
1998
- 1998-06-24 HK HK98106524A patent/HK1007312A1/xx not_active IP Right Cessation
-
1999
- 1999-02-26 US US09/261,609 patent/US6093819A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU655002B2 (en) | 1994-12-01 |
WO1992013859A1 (en) | 1992-08-20 |
JPH06504995A (ja) | 1994-06-09 |
KR100213936B1 (ko) | 1999-08-02 |
HK1007312A1 (en) | 1999-04-09 |
AU1185892A (en) | 1992-09-07 |
DE69220565D1 (de) | 1997-07-31 |
EP0569421B1 (en) | 1997-06-25 |
US5910589A (en) | 1999-06-08 |
KR930703320A (ko) | 1993-11-29 |
ATE154803T1 (de) | 1997-07-15 |
DK0569421T3 (da) | 1997-09-01 |
DE69220565T2 (de) | 1997-12-11 |
CA2101640C (en) | 2002-07-09 |
NZ241442A (en) | 1994-11-25 |
JP2618578B2 (ja) | 1997-06-11 |
CA2101640A1 (en) | 1992-08-01 |
US6093819A (en) | 2000-07-25 |
PT100074A (pt) | 1993-06-30 |
PT100074B (pt) | 1999-06-30 |
ZA92606B (en) | 1992-12-30 |
GR3023917T3 (en) | 1997-09-30 |
IE920294A1 (en) | 1992-07-29 |
GB9102127D0 (en) | 1991-03-13 |
EP0569421A1 (en) | 1993-11-18 |
MX9200398A (es) | 1992-07-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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