DE69216693D1 - Platin(II)-Komplex und Antitumormittel - Google Patents

Platin(II)-Komplex und Antitumormittel

Info

Publication number
DE69216693D1
DE69216693D1 DE69216693T DE69216693T DE69216693D1 DE 69216693 D1 DE69216693 D1 DE 69216693D1 DE 69216693 T DE69216693 T DE 69216693T DE 69216693 T DE69216693 T DE 69216693T DE 69216693 D1 DE69216693 D1 DE 69216693D1
Authority
DE
Germany
Prior art keywords
carbon atoms
platinum
complex
represent
tumor agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69216693T
Other languages
English (en)
Other versions
DE69216693T2 (de
Inventor
Go Hata
Tatsuya Kaneko
Hideki Kawai
Masato Mutoh
Hideyuki Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of DE69216693D1 publication Critical patent/DE69216693D1/de
Publication of DE69216693T2 publication Critical patent/DE69216693T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69216693T 1991-06-10 1992-06-10 Platin(II)-Komplex und Antitumormittel Expired - Fee Related DE69216693T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13802991 1991-06-10

Publications (2)

Publication Number Publication Date
DE69216693D1 true DE69216693D1 (de) 1997-02-27
DE69216693T2 DE69216693T2 (de) 1997-05-07

Family

ID=15212384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69216693T Expired - Fee Related DE69216693T2 (de) 1991-06-10 1992-06-10 Platin(II)-Komplex und Antitumormittel

Country Status (11)

Country Link
US (1) US5348950A (de)
EP (1) EP0518645B1 (de)
JP (1) JPH05178873A (de)
KR (1) KR960010017B1 (de)
AT (1) ATE147747T1 (de)
CA (1) CA2070497C (de)
DE (1) DE69216693T2 (de)
DK (1) DK0518645T3 (de)
ES (1) ES2096721T3 (de)
GR (1) GR3022607T3 (de)
TW (1) TW221443B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0704453A4 (de) * 1994-04-19 1998-07-29 Toray Industries Neuer platin-(ii)-komplex und medikament gegen maligne tumore
US6316652B1 (en) * 1995-06-06 2001-11-13 Kosta Steliou Drug mitochondrial targeting agents
US8048870B2 (en) * 2005-01-11 2011-11-01 Batarseh Kareem I Apoptosis-inducing antineoplastic silver (I) coordination complexes
DE102005047308A1 (de) * 2005-09-30 2007-04-05 Martin-Luther-Universität Halle-Wittenberg Platin(II)Verbindungen aus 2-substituierten Propan-1,3-diaminen zur Verwendung als Chemotherapeutikum

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980347A (en) * 1986-10-15 1990-12-25 Toray Industries Platinum complex, process for preparing same and antitumor agent
US4912100A (en) * 1986-10-15 1990-03-27 Toray Industries, Inc. Platinum complex, process for preparing same and antitumor agent
EP0341318A4 (en) * 1987-11-11 1990-10-10 Toray Industries, Inc. Novel platinum (ii) complex, process for preparing the same, and therapeutic agent for malignant tumor
EP0345356A4 (en) * 1987-11-11 1990-10-10 Toray Industries, Inc. Platinum complex and therapeutic agent for malignant tumor
JPH01313488A (ja) * 1988-06-13 1989-12-18 Toray Ind Inc 新規白金含有化合物および悪性腫瘍治療剤
EP0457921B1 (de) * 1989-12-12 1996-10-09 Toray Industries, Inc. Neuer platin(ii)komplex und mittel für die behandlung von bösartigen tumoren

Also Published As

Publication number Publication date
DK0518645T3 (da) 1997-02-03
ES2096721T3 (es) 1997-03-16
EP0518645A1 (de) 1992-12-16
CA2070497A1 (en) 1992-12-11
US5348950A (en) 1994-09-20
EP0518645B1 (de) 1997-01-15
TW221443B (de) 1994-03-01
DE69216693T2 (de) 1997-05-07
KR960010017B1 (ko) 1996-07-25
ATE147747T1 (de) 1997-02-15
CA2070497C (en) 1999-05-25
KR930000529A (ko) 1993-01-15
JPH05178873A (ja) 1993-07-20
GR3022607T3 (en) 1997-05-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee