ES2096721T3 - Complejo de platino (ii) y agente antitumoral. - Google Patents

Complejo de platino (ii) y agente antitumoral.

Info

Publication number
ES2096721T3
ES2096721T3 ES92305328T ES92305328T ES2096721T3 ES 2096721 T3 ES2096721 T3 ES 2096721T3 ES 92305328 T ES92305328 T ES 92305328T ES 92305328 T ES92305328 T ES 92305328T ES 2096721 T3 ES2096721 T3 ES 2096721T3
Authority
ES
Spain
Prior art keywords
platinum
complex
atoms
carbon
carbon atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92305328T
Other languages
English (en)
Inventor
Go Hata
Tatsuya Kaneko
Hideki Kawai
Masato Mutoh
Hideyuki Hashimoto
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toray Industries Inc
Original Assignee
Toray Industries Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toray Industries Inc filed Critical Toray Industries Inc
Application granted granted Critical
Publication of ES2096721T3 publication Critical patent/ES2096721T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40—Radicals substituted by oxygen atoms
    • C07D307/46—Doubly bound oxygen atoms, or two oxygen atoms singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTA UN COMPLEJO DE PLATINO (II) QUE SE REPRESENTA POR LA FORMULA GENERAL (A), EN LA CUAL R1 REPRESENTA UN RADICAL DE HIDROCARBONO QUE TIENE ENTRE 1 Y 10 ATOMOS DE CARBONO, R2 Y R3 REPRESENTAN CADA UNA UN ATOMO DE HIDROGENO O UN RADICAL DE HIDROCARBONO DE ENTRE 1 Y 10 ATOMOS DE CARBONO, O R2 Y R3, JUNTAS, PUEDEN FORMAR -(CH2)4 UEDEN FORMAR -(CH2)4UNA MOLECULA DE AMONIACO O UN MONODENTADO E Y REPRESENTA CADA UNA UNA MOLECULA DE AMONIACO O UN AMINO MONODENTADO QUE TIENE ENTRE 1 Y 7 ATOMOS DE CARBONO O BIEN X E Y, JUNTAS, REPRESENTAN UN AMINO QUE TIENE ENTRE 1 Y 7 ATOMOS DE CARBONO O BIEN X E Y, JUNTAS, PUEDEN FORMAR UN DIAMINO BIDENTADO QUE TIENE ENTRE 2 Y 10 ATOMOS DE CARBONO. LOS COMPUESTOS SON UTILES PARA EL TRATAMIENTO DE TUMORES.
ES92305328T 1991-06-10 1992-06-10 Complejo de platino (ii) y agente antitumoral. Expired - Lifetime ES2096721T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP13802991 1991-06-10

Publications (1)

Publication Number Publication Date
ES2096721T3 true ES2096721T3 (es) 1997-03-16

Family

ID=15212384

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92305328T Expired - Lifetime ES2096721T3 (es) 1991-06-10 1992-06-10 Complejo de platino (ii) y agente antitumoral.

Country Status (11)

Country Link
US (1) US5348950A (es)
EP (1) EP0518645B1 (es)
JP (1) JPH05178873A (es)
KR (1) KR960010017B1 (es)
AT (1) ATE147747T1 (es)
CA (1) CA2070497C (es)
DE (1) DE69216693T2 (es)
DK (1) DK0518645T3 (es)
ES (1) ES2096721T3 (es)
GR (1) GR3022607T3 (es)
TW (1) TW221443B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0704453A4 (en) * 1994-04-19 1998-07-29 Toray Industries NEW PLATINUM (II) COMPLEX AND MEDICINE AGAINST MALIGNE TUMORS
US6316652B1 (en) * 1995-06-06 2001-11-13 Kosta Steliou Drug mitochondrial targeting agents
US8048870B2 (en) * 2005-01-11 2011-11-01 Batarseh Kareem I Apoptosis-inducing antineoplastic silver (I) coordination complexes
DE102005047308A1 (de) * 2005-09-30 2007-04-05 Martin-Luther-Universität Halle-Wittenberg Platin(II)Verbindungen aus 2-substituierten Propan-1,3-diaminen zur Verwendung als Chemotherapeutikum

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980347A (en) * 1986-10-15 1990-12-25 Toray Industries Platinum complex, process for preparing same and antitumor agent
US4912100A (en) * 1986-10-15 1990-03-27 Toray Industries, Inc. Platinum complex, process for preparing same and antitumor agent
EP0341318A4 (en) * 1987-11-11 1990-10-10 Toray Industries, Inc. Novel platinum (ii) complex, process for preparing the same, and therapeutic agent for malignant tumor
EP0345356A4 (en) * 1987-11-11 1990-10-10 Toray Industries, Inc. Platinum complex and therapeutic agent for malignant tumor
JPH01313488A (ja) * 1988-06-13 1989-12-18 Toray Ind Inc 新規白金含有化合物および悪性腫瘍治療剤
EP0457921B1 (en) * 1989-12-12 1996-10-09 Toray Industries, Inc. Novel platinum (ii) complex and drug for treating malignant tumor

Also Published As

Publication number Publication date
DK0518645T3 (da) 1997-02-03
EP0518645A1 (en) 1992-12-16
CA2070497A1 (en) 1992-12-11
US5348950A (en) 1994-09-20
EP0518645B1 (en) 1997-01-15
TW221443B (es) 1994-03-01
DE69216693T2 (de) 1997-05-07
KR960010017B1 (ko) 1996-07-25
DE69216693D1 (de) 1997-02-27
ATE147747T1 (de) 1997-02-15
CA2070497C (en) 1999-05-25
KR930000529A (ko) 1993-01-15
JPH05178873A (ja) 1993-07-20
GR3022607T3 (en) 1997-05-31

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