DE69214656D1 - Therapeutisches verfahren zur behandlung von iddm - Google Patents
Therapeutisches verfahren zur behandlung von iddmInfo
- Publication number
- DE69214656D1 DE69214656D1 DE69214656T DE69214656T DE69214656D1 DE 69214656 D1 DE69214656 D1 DE 69214656D1 DE 69214656 T DE69214656 T DE 69214656T DE 69214656 T DE69214656 T DE 69214656T DE 69214656 D1 DE69214656 D1 DE 69214656D1
- Authority
- DE
- Germany
- Prior art keywords
- alpha interferon
- therapeutic method
- neutralizing antibodies
- antagonist
- treating iddm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cell Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75230991A | 1991-08-30 | 1991-08-30 | |
PCT/US1992/007094 WO1993004699A1 (en) | 1991-08-30 | 1992-08-19 | Therapeutic method for iddm |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69214656D1 true DE69214656D1 (de) | 1996-11-21 |
DE69214656T2 DE69214656T2 (de) | 1997-03-13 |
Family
ID=25025756
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69214656T Expired - Lifetime DE69214656T2 (de) | 1991-08-30 | 1992-08-19 | Therapeutisches verfahren zur behandlung von iddm |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0601052B1 (de) |
JP (1) | JPH06510061A (de) |
AT (1) | ATE144149T1 (de) |
DE (1) | DE69214656T2 (de) |
DK (1) | DK0601052T3 (de) |
ES (1) | ES2092698T3 (de) |
GR (1) | GR3022092T3 (de) |
WO (1) | WO1993004699A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU7782894A (en) * | 1993-09-17 | 1995-04-03 | Laboratoire Europeen De Biotechnologie S.A. | Pharmaceutical composition comprising monoclonal antibodies against the interferon receptor, with neutralizing activity against type i interferon |
US7285526B2 (en) | 1995-07-14 | 2007-10-23 | Meiogen Biotechnology Corporation | Interferon antagonists useful for the treatment of interferon related diseases |
EP0859633A2 (de) * | 1996-08-16 | 1998-08-26 | Kurt B. Osther | Behandlungsmethode für diabetis |
AU761577C (en) | 1997-12-08 | 2004-02-05 | Genentech Inc. | Human interferon-epsilon: a type I interferon |
ZA9811070B (en) | 1997-12-08 | 2000-07-03 | Genentech Inc | Type I interferons. |
GB0001710D0 (en) * | 2000-01-25 | 2000-03-15 | Pharma Pacific Pty Ltd | Therapeutic treatment |
DE60239522D1 (de) * | 2001-01-09 | 2011-05-05 | Baylor Res Inst Dallas | Verfahren zur behandlung von autoimmunerkrankungen bei einem probanden und diagnostische in-vitro-assays |
ES2313039T3 (es) | 2003-04-23 | 2009-03-01 | Medarex, Inc. | Composiciones y procedimientos para la terapia de enfermedad inflamatoria intestinal. |
WO2005059106A2 (en) | 2003-12-10 | 2005-06-30 | Medarex, Inc. | Interferon alpha antibodies and their uses |
RU2600884C2 (ru) | 2004-06-21 | 2016-10-27 | Е. Р. Сквибб энд Сонз, Эл,Эл.Си | Антитела рецептора 1 интерферона альфа и их применение |
JP5837730B2 (ja) | 2005-02-10 | 2015-12-24 | ベイラー リサーチ インスティテュートBaylor Research Institute | 抗インターフェロンアルファモノクローナル抗体及び使用方法 |
US7888481B2 (en) | 2005-02-10 | 2011-02-15 | Baylor Research Institute | Anti-interferon alpha monoclonal antibodies and methods for use |
JP5208733B2 (ja) | 2005-06-29 | 2013-06-12 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 組換えインターフェロンα2(IFNα2)変異体 |
RU2532832C2 (ru) | 2008-05-07 | 2014-11-10 | Аргос Терапьютикс, Инк. | Гуманизированные антитела против альфа-интерферона человека |
WO2019040674A1 (en) | 2017-08-22 | 2019-02-28 | Sanabio, Llc | SOLUBLE INTERFERON RECEPTORS AND USES THEREOF |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1335792C (en) * | 1987-08-18 | 1995-06-06 | Chaim O. Jacob | Method and dosage form using an antagonist to gamma interferon to control mhc-associated autoimmune disease |
IL88377A (en) * | 1988-11-14 | 1996-09-12 | Yeda Res & Dev | Cloning and expression of a protein which modulates cellular response to type I interferon |
-
1992
- 1992-08-19 JP JP5505234A patent/JPH06510061A/ja active Pending
- 1992-08-19 DE DE69214656T patent/DE69214656T2/de not_active Expired - Lifetime
- 1992-08-19 WO PCT/US1992/007094 patent/WO1993004699A1/en active IP Right Grant
- 1992-08-19 EP EP92918792A patent/EP0601052B1/de not_active Expired - Lifetime
- 1992-08-19 AT AT92918792T patent/ATE144149T1/de active
- 1992-08-19 ES ES92918792T patent/ES2092698T3/es not_active Expired - Lifetime
- 1992-08-19 DK DK92918792.0T patent/DK0601052T3/da active
-
1996
- 1996-12-18 GR GR960403539T patent/GR3022092T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ATE144149T1 (de) | 1996-11-15 |
ES2092698T3 (es) | 1996-12-01 |
EP0601052A1 (de) | 1994-06-15 |
DE69214656T2 (de) | 1997-03-13 |
GR3022092T3 (en) | 1997-03-31 |
EP0601052B1 (de) | 1996-10-16 |
DK0601052T3 (da) | 1996-11-18 |
WO1993004699A1 (en) | 1993-03-18 |
JPH06510061A (ja) | 1994-11-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R071 | Expiry of right |
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