DE69211439D1 - Bestimmung - Google Patents

Bestimmung

Info

Publication number
DE69211439D1
DE69211439D1 DE69211439T DE69211439T DE69211439D1 DE 69211439 D1 DE69211439 D1 DE 69211439D1 DE 69211439 T DE69211439 T DE 69211439T DE 69211439 T DE69211439 T DE 69211439T DE 69211439 D1 DE69211439 D1 DE 69211439D1
Authority
DE
Germany
Prior art keywords
sample
determination
protease
treating
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69211439T
Other languages
English (en)
Other versions
DE69211439T2 (de
Inventor
Julie M Staniford
John A Power
John A Lovelady
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euroapi UK Ltd
Original Assignee
Genzyme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genzyme Ltd filed Critical Genzyme Ltd
Publication of DE69211439D1 publication Critical patent/DE69211439D1/de
Application granted granted Critical
Publication of DE69211439T2 publication Critical patent/DE69211439T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69211439T 1991-07-29 1992-07-27 Bestimmung Expired - Lifetime DE69211439T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919116315A GB9116315D0 (en) 1991-07-29 1991-07-29 Assay

Publications (2)

Publication Number Publication Date
DE69211439D1 true DE69211439D1 (de) 1996-07-18
DE69211439T2 DE69211439T2 (de) 1997-01-16

Family

ID=10699146

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69211439T Expired - Lifetime DE69211439T2 (de) 1991-07-29 1992-07-27 Bestimmung

Country Status (12)

Country Link
US (1) US5370990A (de)
EP (1) EP0526150B1 (de)
JP (2) JP3034698B2 (de)
AT (1) ATE139264T1 (de)
AU (1) AU655646B2 (de)
CA (1) CA2074772C (de)
DE (1) DE69211439T2 (de)
DK (1) DK0526150T3 (de)
ES (1) ES2088549T3 (de)
GB (1) GB9116315D0 (de)
GR (1) GR3020627T3 (de)
IE (1) IE75365B1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5792623A (en) * 1992-04-06 1998-08-11 Immuno Aktiengesellschaft Method for producing activated blood factors with a protease and a detergent
AT397390B (de) * 1992-04-06 1994-03-25 Immuno Ag Verfahren zur spaltung von proteinen
DE69519760T2 (de) * 1994-03-03 2001-08-02 Kyoto Daiichi Kagaku Kk Fructosyl-Aminosäureoxidase und Verfahren zu deren Herstellung
DE4425162A1 (de) * 1994-07-18 1996-01-25 Boehringer Mannheim Gmbh Verfahren zur quantitativen Bestimmung von glykierten Proteinen
US5712138A (en) * 1994-10-05 1998-01-27 Kyoto Daiichi Kagaku Co., Ltd. Fructosyl amino acid oxidase
PL183162B1 (pl) * 1995-05-05 2002-05-31 Genzyme Ltd Sposób oznaczania glikoproteiny oraz zestaw do oznaczania glikoproteiny
US5712167A (en) * 1995-07-19 1998-01-27 Kyoto Dai-Ichi Kagaku Co., Ltd. Method of measuring Amadori compound by light scattering
WO1997013872A1 (fr) * 1995-10-12 1997-04-17 Kyoto Daiichi Kagaku Co., Ltd. Procede pour doser les composes d'amadori
US5639672A (en) * 1995-10-16 1997-06-17 Lxn Corporation Electrochemical determination of fructosamine
WO1997020039A1 (fr) * 1995-11-30 1997-06-05 Kyoto Daiichi Kagaku Co., Ltd. Oxydase de fructosylaminoacides, son procede d'obtention, et methode d'essai des composes d'amadori utilisant ladite oxydase
WO1997021818A1 (fr) * 1995-12-14 1997-06-19 Kyoto Daiichi Kagaku Co., Ltd. Nouvelle oxydase d'acide amine fructosyle provenant d'un champignon du genre penicillium
JP4061348B2 (ja) * 1997-04-24 2008-03-19 アークレイ株式会社 糖化タンパク質の酵素的測定方法
US20020010229A1 (en) * 1997-09-02 2002-01-24 Marshall Medoff Cellulosic and lignocellulosic materials and compositions and composites made therefrom
JP3987900B2 (ja) * 1997-11-26 2007-10-10 アークレイ株式会社 糖化タンパク質の測定方法
DE60013409T2 (de) * 1999-02-22 2005-09-22 Arkray, Inc. Alpha-glykosilierte aminosäure freisetzendes enzym
WO2000061732A1 (en) * 1999-04-12 2000-10-19 Arkray, Inc. α-GLYCATED AMINO ACID RELEASING ENZYME
JP3949854B2 (ja) 1999-10-01 2007-07-25 キッコーマン株式会社 糖化蛋白質の測定方法
US20030226769A1 (en) * 2000-05-23 2003-12-11 Koji Sode Kit for assaying saccharified protein
EP1291438A1 (de) * 2000-06-07 2003-03-12 BML, Inc. Verfahren zum nachweis von saccharifiziertem albumin
WO2002006519A1 (fr) 2000-07-14 2002-01-24 Arkray, Inc. Procede pour determiner de maniere selective le taux d'hemoglobine glycosylee
JPWO2002022698A1 (ja) * 2000-09-12 2004-01-22 早出 広司 酵素模倣ポリマー
EP2248909B1 (de) 2001-01-31 2016-09-28 Asahi Kasei Pharma Corporation Zusammensetzung zum Testen glykierter Proteine
US6951728B2 (en) * 2002-05-10 2005-10-04 Lifescan, Inc. Multilayer reagent test strips to quantify glycated protein in a physiological sample
US7299805B2 (en) * 2002-06-07 2007-11-27 Marctec, Llc Scaffold and method for implanting cells
AU2003275613A1 (en) 2002-10-23 2004-05-13 Daiichi Pure Chemicals Co., Ltd. Novel fructosyl peptide oxidase and utilization thereof
JP4226341B2 (ja) * 2003-01-14 2009-02-18 旭化成ファーマ株式会社 糖化リン脂質の分析方法および分析試薬
JP4565807B2 (ja) * 2003-01-22 2010-10-20 旭化成ファーマ株式会社 糖化タンパク質測定用プロテアーゼ
JP4504923B2 (ja) 2003-05-21 2010-07-14 旭化成ファーマ株式会社 ヘモグロビンA1c測定法およびそれに用いる酵素とその製造法
US7951553B2 (en) 2003-11-19 2011-05-31 Sekisui Medical Co., Ltd. Method of assaying glycated protein
EP1788081A4 (de) 2004-08-05 2008-09-10 Asahi Kasei Pharma Corp Reagens mit proteasereaktionspromotor und/oder farbstoffstabilisator
DE102004050209A1 (de) * 2004-10-15 2006-04-20 Merck Patent Gmbh Mittel und Verfahren zum Nachweis von Furfuralen
US7820404B2 (en) 2005-05-06 2010-10-26 Arkray, Inc. Protein cleavage method and use thereof
JP5204483B2 (ja) 2005-07-19 2013-06-05 キッコーマン株式会社 糖化蛋白質の測定方法および測定キット
US20070026523A1 (en) * 2005-07-27 2007-02-01 Daiichi Pure Chemicals Co., Ltd. Method for stabilizing leuco dye
EP2520650A3 (de) 2006-04-25 2012-11-21 Kikkoman Corporation Eukaryotische Amadoriase mit ausgezeichneter Wärmestabilität, Gen und rekombinante DNA für die eukaryotische Amadoriase und Verfahren zur Herstellung der eukaryotischen Amadoriase mit ausgezeichneter Wärmestabilität
JP2008125368A (ja) 2006-11-16 2008-06-05 Amano Enzyme Inc 新規なジペプチド分解酵素及びその製造方法並びにジペプチド分解酵素を用いる糖化蛋白質等の測定方法及びそれに用いる試薬組成物
JP4697809B2 (ja) * 2007-02-22 2011-06-08 旭化成ファーマ株式会社 ロイコ色素の安定化方法
US20120077278A1 (en) * 2009-06-08 2012-03-29 Protea Biopharma N.V. Methods and kits for detecting, diagnosing and monitoring diseases
EP2287295A1 (de) 2009-08-03 2011-02-23 Roche Diagnostics GmbH Mutierte Fructosyl Amino Acid Oxidase
CN103080308B (zh) 2010-08-06 2015-08-05 龟甲万株式会社 底物特异性得到改变的阿马多里酶
US9708586B2 (en) 2010-08-06 2017-07-18 Kikkoman Corporation Amadoriase having altered substrate specificity
US8560127B2 (en) 2011-01-13 2013-10-15 Honeywell International Inc. HVAC control with comfort/economy management
EP2808386B1 (de) 2011-12-28 2018-11-28 Kikkoman Corporation Amadoriase mit verbesserter thermischer stabilität, gen und rekombinante dna davon sowie verfahren zur herstellung von amadoriase mit verbesserter thermischer stabilität
KR101207418B1 (ko) 2012-02-10 2012-12-04 주식회사 아이센스 효소법을 이용하는 당화혈색소 정량분석용 용혈시약 조성물
JP6401056B2 (ja) 2012-04-27 2018-10-03 キッコーマン株式会社 フルクトシルヘキサペプチドに作用する改変型アマドリアーゼ
WO2015020200A1 (ja) 2013-08-09 2015-02-12 キッコーマン株式会社 改変型アマドリアーゼ及びその製造法、並びにアマドリアーゼの界面活性剤耐性向上剤及びこれを用いたHbA1c測定用組成物
US10697979B2 (en) 2013-10-25 2020-06-30 Kikkoman Corporation Method for measurement of HbA1c using amadoriase that reacts with glycated peptide
CN105683374A (zh) 2013-10-25 2016-06-15 龟甲万株式会社 血红蛋白A1c的测定方法和测定试剂盒
CN107148475A (zh) 2014-10-24 2017-09-08 龟甲万株式会社 脱氢酶活性提高的阿马多里酶
EP3216865B1 (de) 2014-11-07 2020-09-30 Kikkoman Corporation Amadoriase mit erhöhter tolerance gegenüber anionischen tensiden
WO2016159384A1 (ja) 2015-04-03 2016-10-06 キッコーマン株式会社 比活性が向上したアマドリアーゼ
US10802459B2 (en) 2015-04-27 2020-10-13 Ademco Inc. Geo-fencing with advanced intelligent recovery
KR102596402B1 (ko) 2016-04-22 2023-10-31 기꼬만 가부시키가이샤 HbA1c 디히드로게나아제
JP7458703B2 (ja) 2016-07-13 2024-04-01 キッコーマン株式会社 反応促進剤
CN109682796A (zh) 2017-10-02 2019-04-26 爱科来株式会社 糖化蛋白质的测定
EP3760724A4 (de) 2018-02-27 2022-01-05 Kikkoman Corporation Neues enzym und verfahren zur bestimmung von pentosidin unter verwendung desselben
JP7492513B2 (ja) 2019-07-01 2024-05-29 旭化成ファーマ株式会社 フェロシアン化物の酸化還元電位を大きくするプロテアーゼの安定化剤を含む糖化タンパク質測定試薬、糖化タンパク質の測定方法、糖化タンパク質測定試薬の保存方法、及び糖化タンパク質測定試薬の安定化方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2105445A5 (de) * 1970-09-07 1972-04-28 Inst Francais Du Petrole
JPH0665300B2 (ja) * 1985-05-22 1994-08-24 財団法人野田産業科学研究所 フルクトシルアミノ酸オキシダーゼ
JPS61280297A (ja) * 1985-06-04 1986-12-10 Noda Sangyo Kagaku Kenkyusho アマドリ化合物の定量法及びその定量用試薬
US5002893A (en) * 1985-09-19 1991-03-26 Isolab, Inc. Single color reading method for determining fructosamine
US4797473A (en) * 1986-06-25 1989-01-10 Regents Of The University Of Minnesota Monoclonal antibodies to unreduced, nonenzymatically-glycated proteins
DE3743405A1 (de) * 1987-05-14 1988-11-24 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fructosamin
DE3732688A1 (de) * 1987-09-29 1989-04-13 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung des serumfructosamingehalts sowie hierfuer geeignetes reagenzgemisch
DE3822749A1 (de) * 1988-07-05 1990-01-11 Boehringer Mannheim Gmbh Fructosamin-calibrator
DE3824562A1 (de) * 1988-07-19 1990-02-01 Boehringer Mannheim Gmbh Verfahren zur bestimmung von fructosamin
JPH02195900A (ja) * 1989-01-25 1990-08-02 Sanyo Chem Ind Ltd 糖化蛋白の測定法および測定試薬
US5110745A (en) * 1989-06-01 1992-05-05 The Trustees Of The University Of Pennsylvania Methods of detecting glycated proteins
US4956301A (en) * 1989-11-02 1990-09-11 Miles Inc. Test device and method of assaying for fructosamines
JP2601356B2 (ja) * 1989-11-14 1997-04-16 財団法人野田産業科学研究所 フルクトシルアミン・オキシダーゼ、その製造法、該酵素を用いたアマドリ化合物の定量法及びその試薬

Also Published As

Publication number Publication date
JP3068061B2 (ja) 2000-07-24
DE69211439T2 (de) 1997-01-16
JPH05192193A (ja) 1993-08-03
JP3034698B2 (ja) 2000-04-17
GB9116315D0 (en) 1991-09-11
ATE139264T1 (de) 1996-06-15
ES2088549T3 (es) 1996-08-16
GR3020627T3 (en) 1996-10-31
AU655646B2 (en) 1995-01-05
IE75365B1 (en) 1997-08-27
EP0526150B1 (de) 1996-06-12
US5370990A (en) 1994-12-06
CA2074772A1 (en) 1993-01-30
IE922455A1 (en) 1993-02-10
CA2074772C (en) 1998-06-23
EP0526150A1 (de) 1993-02-03
AU2045792A (en) 1993-02-04
JPH11127895A (ja) 1999-05-18
DK0526150T3 (da) 1996-07-01

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