DE69206121T2 - Methode zur Reinigung des Alpha-L-Aspartyl-L-Phenylalanin-Methylesters. - Google Patents

Methode zur Reinigung des Alpha-L-Aspartyl-L-Phenylalanin-Methylesters.

Info

Publication number
DE69206121T2
DE69206121T2 DE69206121T DE69206121T DE69206121T2 DE 69206121 T2 DE69206121 T2 DE 69206121T2 DE 69206121 T DE69206121 T DE 69206121T DE 69206121 T DE69206121 T DE 69206121T DE 69206121 T2 DE69206121 T2 DE 69206121T2
Authority
DE
Germany
Prior art keywords
aspartyl
purifying
alpha
methyl ester
phenylalanine methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69206121T
Other languages
English (en)
Other versions
DE69206121D1 (de
Inventor
Tadashi Takemoto
Katsumi Sugiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Co Inc
Original Assignee
Ajinomoto Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co Inc filed Critical Ajinomoto Co Inc
Publication of DE69206121D1 publication Critical patent/DE69206121D1/de
Application granted granted Critical
Publication of DE69206121T2 publication Critical patent/DE69206121T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
DE69206121T 1992-01-14 1992-12-29 Methode zur Reinigung des Alpha-L-Aspartyl-L-Phenylalanin-Methylesters. Expired - Fee Related DE69206121T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4004890A JPH05194587A (ja) 1992-01-14 1992-01-14 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの精製法

Publications (2)

Publication Number Publication Date
DE69206121D1 DE69206121D1 (de) 1995-12-21
DE69206121T2 true DE69206121T2 (de) 1996-07-04

Family

ID=11596276

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69206121T Expired - Fee Related DE69206121T2 (de) 1992-01-14 1992-12-29 Methode zur Reinigung des Alpha-L-Aspartyl-L-Phenylalanin-Methylesters.

Country Status (5)

Country Link
US (1) US5432262A (de)
EP (1) EP0556485B1 (de)
JP (1) JPH05194587A (de)
CA (1) CA2087325C (de)
DE (1) DE69206121T2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6225493B1 (en) * 2000-08-21 2001-05-01 The Nutrasweet Company Metal ion assisted N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester isomer resolution

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5848984B2 (ja) * 1974-10-01 1983-11-01 ソニー株式会社 カラ−インキヨクセンカンノスクリ−ン ノ セイゾウホウホウ
JPS6049199B2 (ja) * 1979-04-10 1985-10-31 東ソー株式会社 α−Ｌ−アスパルチル−Ｌ−フエニルアラニン低級アルキルエステルの精製法
JPS60174799A (ja) * 1984-02-21 1985-09-09 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの製造法
AU586669B2 (en) * 1985-03-29 1989-07-20 Mitsui Toatsu Chemicals Inc. Preparation process of ```-L-aspartyl-L-phenylalanine methyl ester or hydrochloride thereof
US4835303A (en) * 1986-08-12 1989-05-30 Toyo Soda Manufacturing Company, Ltd. Process for producing dry α-L-aspartyl-L-phenylalanine methyl ester
US4897507A (en) * 1987-07-22 1990-01-30 Ajinomoto Co., Inc. Method for producing α-L-aspartyl-L-phenylalanine derivatives
CA2017137A1 (en) * 1989-05-22 1990-11-22 Shigeaki Irino Method for crystallizing &-l-aspartyl-l-phenylalanine methyl ester
DE69112344T2 (de) * 1990-11-05 1996-04-18 Mitsui Toatsu Chemicals Verbessertes Verfahren zur Kristallisierung von Alpha-Aspartyl-L-Phenylalaninmethylester aus deren Lösung.
JPH05125095A (ja) * 1991-05-23 1993-05-21 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルの晶析方法
JP2927070B2 (ja) * 1991-05-23 1999-07-28 味の素株式会社 α−Ｌ−アスパルチル−Ｌ−フェニルアラニンメチルエステルの製造方法

Also Published As

Publication number Publication date
EP0556485B1 (de) 1995-11-15
CA2087325C (en) 2002-11-19
CA2087325A1 (en) 1993-07-15
JPH05194587A (ja) 1993-08-03
EP0556485A1 (de) 1993-08-25
US5432262A (en) 1995-07-11
DE69206121D1 (de) 1995-12-21

Similar Documents

Publication Publication Date Title
DE69323983D1 (de) Methode zur Modifizierung des Fettdruckes von Buchstaben
DE69422575T2 (de) System zur Erklärung von Austellungsstücken
DE69309763D1 (de) Vorrichtung zur Herstellung von Rohren
DE69421211T2 (de) System zur Abwasserbehandlung
DE595783T1 (de) System zur Ultraschallbehandlung.
DE59200574D1 (de) Verfahren zur Herstellung von Dialkylcarbonaten.
DE69739258D1 (de) Verfahren zur Herstellung von Polyelektrolyten
DE69124172D1 (de) Verfahren zur Reinigung von Edelgas
EE03048B1 (et) Meetod lovastatiini valmistamiseks
DE59203649D1 (de) Verfahren zur Herstellung von Dialkylcarbonaten.
DE59200262D1 (de) Verfahren zur Reinigung von Bisphenolen.
DE69022707D1 (de) Methode zur Fluordecarboxylierung.
DE69423487D1 (de) Einrichtung zur aquakultur
DE69331992T2 (de) Verfahren zur hochaufreinigung von menschlichem serumalbumin
DE69324692D1 (de) Katalysator und methode zur dessen herstellung
DE69204493T2 (de) Verfahren zur Reinigung von Dimethylcarbonat.
DE69513313T2 (de) Verfahren zur Herstellung von Nukleinsäurebasenderivaten
DE69206121T2 (de) Methode zur Reinigung des Alpha-L-Aspartyl-L-Phenylalanin-Methylesters.
DE29600428U1 (de) System zur sicheren Erfassung von Spielsituationen
DE69203707D1 (de) Verfahren zur Reinigung von Fluorethanen und Chlorfluorethanen.
DE59202706D1 (de) Verfahren zur Herstellung von Dialkylcarbonaten.
DE69602220D1 (de) Verfahren zur Verbesserung der thermischen Stabilität von Sepiolith
DE69300712D1 (de) Verfahren zur Reinigung von L-Phenylalanin.
DE59703759D1 (de) Verfahren zur Herstellung von 4-Hydroxydiphenyl
DE59203788D1 (de) Verfahren zur Herstellung und Reinigung von 1-Amino-2-phenoxy-4-hydroxy-anthrachinon.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee