DE69133399D1 - Methode zur Herstellung von im Wesentlichen monomeren normalen menschlichen Serum-Albumin - Google Patents

Methode zur Herstellung von im Wesentlichen monomeren normalen menschlichen Serum-Albumin

Info

Publication number
DE69133399D1
DE69133399D1 DE69133399T DE69133399T DE69133399D1 DE 69133399 D1 DE69133399 D1 DE 69133399D1 DE 69133399 T DE69133399 T DE 69133399T DE 69133399 T DE69133399 T DE 69133399T DE 69133399 D1 DE69133399 D1 DE 69133399D1
Authority
DE
Germany
Prior art keywords
preparation
composition
essentially
serum albumin
human serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69133399T
Other languages
English (en)
Other versions
DE69133399T2 (de
Inventor
Robert A Tenold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of DE69133399D1 publication Critical patent/DE69133399D1/de
Application granted granted Critical
Publication of DE69133399T2 publication Critical patent/DE69133399T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69133399T 1990-04-19 1991-04-06 Methode zur Herstellung von im Wesentlichen monomeren normalen menschlichen Serum-Albumin Expired - Lifetime DE69133399T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US511362 1983-07-06
US51136290A 1990-04-19 1990-04-19

Publications (2)

Publication Number Publication Date
DE69133399D1 true DE69133399D1 (de) 2004-07-29
DE69133399T2 DE69133399T2 (de) 2005-06-30

Family

ID=24034566

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69133399T Expired - Lifetime DE69133399T2 (de) 1990-04-19 1991-04-06 Methode zur Herstellung von im Wesentlichen monomeren normalen menschlichen Serum-Albumin

Country Status (6)

Country Link
EP (1) EP0452753B1 (de)
JP (2) JP3009242B2 (de)
AT (1) ATE269872T1 (de)
CA (1) CA2040036A1 (de)
DE (1) DE69133399T2 (de)
ES (1) ES2224094T3 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
DK0524681T3 (da) 1991-07-12 2000-04-10 Dsm Nv Fremgangsmåde til oprensning af serumalbumin
JPH07102148B2 (ja) * 1992-05-20 1995-11-08 株式会社ミドリ十字 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US5728553A (en) * 1992-09-23 1998-03-17 Delta Biotechnology Limited High purity albumin and method of producing
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
ES2103236B1 (es) * 1996-01-30 1998-04-16 Grifols Grupo Sa Albumina humana terapeutica con baja capacidad para la fijacion de aluminio.
DK1084136T3 (da) 1998-06-01 2005-01-03 Genentech Inc Adskillelse af monomere af et antistof fra dets multimere ved anvendelse af ionbytterchromatografi
DE19830914C1 (de) * 1998-07-10 1999-06-24 Centeon Pharma Gmbh Verfahren zur Herstellung einer Proteinlösung
GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
WO2000056768A2 (en) * 1999-03-19 2000-09-28 Bayer Corporation Chromatographic albumin process
JP2003040798A (ja) * 2001-07-26 2003-02-13 Nihon Pharmaceutical Co Ltd 低アルミニウム含有アルブミン製剤およびその製造法
KR20180020982A (ko) * 2015-06-26 2018-02-28 훼링 비.브이. 정제 방법 및/또는 바이러스 불활화 처리 방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1196636A (en) * 1967-03-01 1970-07-01 Ustav Ser A Ockovacich Latek O Process for the Preparation of Pure Albumins from Normal and Haemolysed Sera and Plasma
US3926939A (en) * 1973-08-24 1975-12-16 Mikhail Ivanovich Ivanov Method of extracting pure serum albumin from biological fluids using a salt of a carboxylic aliphatic acid
US4156681A (en) * 1974-03-28 1979-05-29 Plasmesco Ag Process for isolating albumin from blood
US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
FR2543448A1 (fr) * 1983-04-01 1984-10-05 Rhone Poulenc Spec Chim Procede de fractionnement du plasma
JPS62294621A (ja) * 1986-06-13 1987-12-22 Green Cross Corp:The アルブミンの回収方法

Also Published As

Publication number Publication date
JP2000095798A (ja) 2000-04-04
EP0452753A1 (de) 1991-10-23
JPH0733800A (ja) 1995-02-03
CA2040036A1 (en) 1991-10-20
EP0452753B1 (de) 2004-06-23
ATE269872T1 (de) 2004-07-15
ES2224094T3 (es) 2005-03-01
JP3009242B2 (ja) 2000-02-14
DE69133399T2 (de) 2005-06-30

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