DE69132404D1 - Varicella-zoster virusantigen - Google Patents

Varicella-zoster virusantigen

Info

Publication number
DE69132404D1
DE69132404D1 DE69132404T DE69132404T DE69132404D1 DE 69132404 D1 DE69132404 D1 DE 69132404D1 DE 69132404 T DE69132404 T DE 69132404T DE 69132404 T DE69132404 T DE 69132404T DE 69132404 D1 DE69132404 D1 DE 69132404D1
Authority
DE
Germany
Prior art keywords
tgp
secretory
present
vzv
antibodies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69132404T
Other languages
English (en)
Other versions
DE69132404T2 (de
Inventor
Abbas Vafai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Research Corp Technologies Inc
Original Assignee
Research Corp Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Research Corp Technologies Inc filed Critical Research Corp Technologies Inc
Application granted granted Critical
Publication of DE69132404D1 publication Critical patent/DE69132404D1/de
Publication of DE69132404T2 publication Critical patent/DE69132404T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/12Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/088Varicella-zoster virus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69132404T 1990-10-04 1991-10-04 Varicella-zoster virusantigen Expired - Fee Related DE69132404T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59276690A 1990-10-04 1990-10-04
PCT/US1991/007280 WO1992006989A1 (en) 1990-10-04 1991-10-04 Varicella-zoster virus antigen

Publications (2)

Publication Number Publication Date
DE69132404D1 true DE69132404D1 (de) 2000-10-12
DE69132404T2 DE69132404T2 (de) 2001-02-15

Family

ID=24371982

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69132404T Expired - Fee Related DE69132404T2 (de) 1990-10-04 1991-10-04 Varicella-zoster virusantigen

Country Status (10)

Country Link
US (1) US6180369B1 (de)
EP (1) EP0504388B1 (de)
JP (1) JP3990445B2 (de)
KR (1) KR920703614A (de)
AT (1) ATE196163T1 (de)
CA (1) CA2068654C (de)
DE (1) DE69132404T2 (de)
DK (1) DK0504388T3 (de)
ES (1) ES2150906T3 (de)
WO (1) WO1992006989A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE210722T1 (de) 1992-07-17 2001-12-15 Merck & Co Inc Methode zur verhinderung von zoster und linderung der mit varicellea verbundenen postherpetischen neuralgie
GB9413751D0 (en) * 1994-07-07 1994-08-24 British Bio Technology Immunodominant peptides
KR970006484A (ko) * 1995-07-27 1997-02-21 수두 바이러스의 당단백질을 대량발현시키는 동물세포주
US6528066B1 (en) * 1999-09-14 2003-03-04 University Of Iowa Research Foundation Variant varicella-zoster viruses and methods of use
EA202092828A1 (ru) * 2018-05-23 2021-03-11 Могам Инститьют Фор Байомедикал Рисерч Антигенный вариант вируса varicella zoster и его применение
CN112941031B (zh) * 2021-02-20 2023-06-27 安徽智飞龙科马生物制药有限公司 一种gE-HEK293细胞的构建方法及其应用

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4008317A (en) 1975-12-29 1977-02-15 Recherche Et Industrie Therapeutiques (R.I.T.) Varicella-zoster virus vaccine and preparation thereof
DE2930706A1 (de) 1979-07-28 1981-02-05 Medac Klinische Spezialpraep Verfahren zum nachweis von erregerspezifischen antikoerpern
US4663277A (en) 1983-05-20 1987-05-05 Profile Diagnostic Sciences Inc. Virus detection method and materials
DE3587991T2 (de) 1984-04-06 1995-07-20 Chiron Corp Rekombinanter herpes simplex gb-gd impfstoff.
US4769239A (en) 1984-08-21 1988-09-06 Merck & Co., Inc. Vaccine against varicella-zoster virus
US4686101A (en) 1985-08-02 1987-08-11 Merck & Co., Inc. Vaccine against varicella-zoster virus
JPH01252279A (ja) 1988-03-31 1989-10-06 Chemo Sero Therapeut Res Inst 帯状疱疹ウイルス糖蛋白質およびその製法
CY1933A (en) 1989-06-27 1990-06-22 Smithkline Biolog Novel compounds
EP0406857B1 (de) * 1989-07-07 1995-05-24 Takeda Chemical Industries, Ltd. Proteine und deren Herstellung
JPH03232897A (ja) * 1989-11-16 1991-10-16 Takeda Chem Ind Ltd ポリペプチドおよびその製造法
US5824319A (en) * 1990-10-04 1998-10-20 Research Corporation Technologies, Inc. Varicella-zoster virus antigen
NL9100989A (nl) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1.

Also Published As

Publication number Publication date
JP3990445B2 (ja) 2007-10-10
CA2068654A1 (en) 1992-04-05
DE69132404T2 (de) 2001-02-15
JPH05502595A (ja) 1993-05-13
ES2150906T3 (es) 2000-12-16
WO1992006989A1 (en) 1992-04-30
CA2068654C (en) 2011-01-04
EP0504388B1 (de) 2000-09-06
EP0504388A4 (en) 1993-04-28
DK0504388T3 (da) 2000-12-27
EP0504388A1 (de) 1992-09-23
ATE196163T1 (de) 2000-09-15
US6180369B1 (en) 2001-01-30
KR920703614A (ko) 1992-12-18

Similar Documents

Publication Publication Date Title
Stampfer et al. Stuck in the middle: structural insights into the role of the gH/gL heterodimer in herpesvirus entry
Spector et al. Protein-protein interactions between human cytomegalovirus IE2-580aa and pUL84 in lytically infected cells
Khattab et al. Three T‐cell epitopes within the C‐terminal 265 amino acids of the matrix protein pp65 of human cytomegalovirus recognized by human lymphocytes
FI20021626A (fi) Immuunimäärityksen reagenssi ja menetelmä hepatiitti C-viruksen (HCV) vasta-aineiden havaitsemiseksi
DK268588A (da) Syntetisk peptidantigen til detektering af hiv-2-infektion
DE69132404D1 (de) Varicella-zoster virusantigen
ATE71141T1 (de) Diagnosesystem zum nachweis von cytomegalovirus.
NO170025C (no) Monoklonalt antistoff til anvendelse in vitro, hybridoma-cellelinje for fremstilling derav samt anvendelse av foerstnevnte
ES8505253A1 (es) Un procedimiento para preparar un organismo unicelular que tiene una secuencia de adn que codifica un plipeptid0 que tiene un determinante inmunorreactivo u antigeno de una glicoproteina de virus de herpes simplex.
Li et al. Expression of Epstein‐Barr‐virus‐related nuclear antigens and B‐cell markers in lymphomas of SIV‐immunosuppressed monkeys
KR920702724A (ko) 수두대상포진 비루스의 당단백 gpiii에 대한 사람의 일클론항체
Franti et al. Immune reactivity of human sera to the glycoprotein B of human herpesvirus 7
Kimura et al. Baculovirus expression, purification, and properties of varicella-zoster virus gE, gI, and the complex they form
KR860004314A (ko) 단순헤르페스 바이러스 항체의 측정방법
Zal et al. Epitope mapping of mouse monoclonal antibodies to the ppUL83 lower matrix phosphoprotein of human cytomegalovirus
EP0687308A4 (de) Rekombinantes kapsidantigen des epstein-barr viruses welches nützlich in einer diagnostischen methode ist
ATE453715T1 (de) Immunreaktive bereiche des glycoproteins gpii des varicella zoster-virus (vzv)
Venables Antibodies to EBV-encoded proteins in rheumatoid arthritis
ATE131731T1 (de) Hiv-2-eho-retrovirus-proteine und -glycoproteine, antikörper gegen sie, verwendung für diagnostische zwecke
Garzelli et al. Epstein-Barr Virus-Induced Autoimmunity through Anti-Idiotype Studies
Gazitt et al. Foster, JR, see K. Miller Fouchard, M., see D. Zagury Friedman, HP, see VL Braciale Gaudernack, G., R. Curry and R. Messner, Rapid identification of human B-lymphocytes and monocytes with rhodamine-labeled
Szewczyk Viral recombinant proteins produced in baculovirus system for tests differentiating infected and vaccinated animals

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee