DE69131685T2 - Verfahren zur herstellung optisch aktiven (-)-2-halo-1-(substituiertes phenyl)ethanols - Google Patents

Verfahren zur herstellung optisch aktiven (-)-2-halo-1-(substituiertes phenyl)ethanols

Info

Publication number
DE69131685T2
DE69131685T2 DE69131685T DE69131685T DE69131685T2 DE 69131685 T2 DE69131685 T2 DE 69131685T2 DE 69131685 T DE69131685 T DE 69131685T DE 69131685 T DE69131685 T DE 69131685T DE 69131685 T2 DE69131685 T2 DE 69131685T2
Authority
DE
Germany
Prior art keywords
ethanols
halo
optically active
substituted phenyl
producing optically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131685T
Other languages
English (en)
Other versions
DE69131685D1 (de
Inventor
Ikuo Sawa
Yuko Konishi
Shunichi Maemoto
Junzo Hasegawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3353491A external-priority patent/JP3067817B2/ja
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Publication of DE69131685D1 publication Critical patent/DE69131685D1/de
Application granted granted Critical
Publication of DE69131685T2 publication Critical patent/DE69131685T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/08—Compounds containing oxirane rings with hydrocarbon radicals, substituted by halogen atoms, nitro radicals or nitroso radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/921—Candida
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/921—Candida
    • Y10S435/924—Candida tropicalis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/938—Pichia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi
    • Y10S435/94—Saccharomyces
    • Y10S435/942—Saccharomyces cerevisiae

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Epoxy Compounds (AREA)
DE69131685T 1990-07-24 1991-07-22 Verfahren zur herstellung optisch aktiven (-)-2-halo-1-(substituiertes phenyl)ethanols Expired - Fee Related DE69131685T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP19580890 1990-07-24
JP3353491A JP3067817B2 (ja) 1990-07-24 1991-02-01 光学活性（−）−２−ハロ−１−（置換フェニル）エタノールの製造法
PCT/JP1991/000973 WO1992001804A1 (en) 1990-07-24 1991-07-22 Process for producing optically active (-)-2-halo-1-(substituted phenyl)ethanol and (-)-substituted styrene oxide

Publications (2)

Publication Number Publication Date
DE69131685D1 DE69131685D1 (de) 1999-11-11
DE69131685T2 true DE69131685T2 (de) 2000-04-27

Family

ID=26372242

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131685T Expired - Fee Related DE69131685T2 (de) 1990-07-24 1991-07-22 Verfahren zur herstellung optisch aktiven (-)-2-halo-1-(substituiertes phenyl)ethanols

Country Status (4)

Country Link
US (1) US5266485A (de)
EP (1) EP0493617B1 (de)
DE (1) DE69131685T2 (de)
WO (1) WO1992001804A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10248277A1 (de) * 2002-10-16 2004-05-06 X-Zyme Gmbh Verfahren zur Herstellung optisch aktiver Verbindungen

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3279671B2 (ja) * 1992-09-28 2002-04-30 鐘淵化学工業株式会社 チエノチオピラン誘導体の製造方法
FR2728568B1 (fr) * 1994-12-23 1997-04-11 Synthelabo Intermediaires de synthese des enantiomeres de l'eliprodil et leur procede de preparation
DE69616122T2 (de) * 1995-03-29 2002-07-04 Sumika Fine Chemicals Co Ltd Verfahren zur Herstellung von (R)-Styroloxiden
JP3529904B2 (ja) * 1995-06-19 2004-05-24 鐘淵化学工業株式会社 光学活性１−ハロ−３−アミノ−４−フェニル−２−ブタノール誘導体の製造法
US5756862A (en) * 1995-08-26 1998-05-26 Nihon Nohyaku Co., Ltd. Production of optically active 2-halo-1-(substituted phenyl)ethanol and substituted styrene oxide
WO2002000585A1 (fr) * 2000-06-27 2002-01-03 Kaneka Corporation Derive de chlorohydroxyacetone et procede de production de derive de chloropropanediol optiquement actif a partir du derive de chlorohydroxyacetone
JPWO2002051781A1 (ja) 2000-12-25 2004-04-22 味の素株式会社 光学活性ハロヒドリン化合物の製造方法
DE10105866A1 (de) * 2001-02-09 2002-08-29 Forschungszentrum Juelich Gmbh Verfahren zur Herstellung von optisch aktiven, propargylischen, terminalen Epoxiden
JP2003000290A (ja) * 2001-06-25 2003-01-07 Kanegafuchi Chem Ind Co Ltd 光学活性（ｒ）−２−クロロ−１−（３′−クロロフェニル）エタノールの製造法
ATE416255T1 (de) * 2002-04-30 2008-12-15 Kaneka Corp Carbonylreduktase, deren gen und verwendung
US7651466B2 (en) 2005-04-13 2010-01-26 Edwards Lifesciences Corporation Pulse contour method and apparatus for continuous assessment of a cardiovascular parameter
DE102006056526A1 (de) * 2006-11-30 2008-06-05 Archimica Gmbh Verfahren zur stereoselektiven Synthese von chiralen Epoxiden durch ADH-Reduktion von alpha-Abgangsgruppen-substituierten Ketonen und Cyclisierung
EP2551351A1 (de) * 2011-07-29 2013-01-30 Interquim, S.A. Verfahren zur Herstellung von optisch aktivem (R)-(-)-1-(2,4-dichlor-phenyl)-2-imidazol-1-yl-ethanol

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4262004A (en) * 1979-06-21 1981-04-14 Janssen Pharmaceutica, N.V. 2,3-Dihydro-imidazo[2,1-b]benzothiazole compositions to treat depressions
JPS59216595A (ja) * 1983-05-24 1984-12-06 Baiorisaac Center:Kk エポキシドの製造方法
JPS61239893A (ja) * 1985-04-13 1986-10-25 Kanegafuchi Chem Ind Co Ltd 光学活性（ｓ）−２−ハロ−１−フエニルエタノ−ルの製造法
JPS62212258A (ja) * 1986-03-13 1987-09-18 東芝セラミツクス株式会社 鋳造用ノズルの製造方法
US4868344A (en) * 1988-03-30 1989-09-19 Aldrich-Boranes, Inc. Novel process of producing phenyl or substituted phenylalkylamine pharmaceutical agents and novel chiral intermediates of high enantiomeric purity useful therein

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10248277A1 (de) * 2002-10-16 2004-05-06 X-Zyme Gmbh Verfahren zur Herstellung optisch aktiver Verbindungen

Also Published As

Publication number Publication date
EP0493617B1 (de) 1999-10-06
DE69131685D1 (de) 1999-11-11
EP0493617A1 (de) 1992-07-08
WO1992001804A1 (en) 1992-02-06
EP0493617A4 (de) 1994-04-27
US5266485A (en) 1993-11-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee