DE69123445T2 - Verfahren zur bestimmung von endotoxinen - Google Patents

Verfahren zur bestimmung von endotoxinen

Info

Publication number
DE69123445T2
DE69123445T2 DE69123445T DE69123445T DE69123445T2 DE 69123445 T2 DE69123445 T2 DE 69123445T2 DE 69123445 T DE69123445 T DE 69123445T DE 69123445 T DE69123445 T DE 69123445T DE 69123445 T2 DE69123445 T2 DE 69123445T2
Authority
DE
Germany
Prior art keywords
endotoxins
determining
determining endotoxins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69123445T
Other languages
English (en)
Other versions
DE69123445D1 (de
Inventor
Shigenori Tanaka
Hiroshi Tamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seikagaku Corp
Original Assignee
Seikagaku Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seikagaku Corp filed Critical Seikagaku Corp
Application granted granted Critical
Publication of DE69123445D1 publication Critical patent/DE69123445D1/de
Publication of DE69123445T2 publication Critical patent/DE69123445T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
DE69123445T 1990-09-28 1991-09-27 Verfahren zur bestimmung von endotoxinen Expired - Fee Related DE69123445T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2257415A JP2957251B2 (ja) 1990-09-28 1990-09-28 エンドトキシンの測定法
PCT/JP1991/001309 WO1992006382A1 (en) 1990-09-28 1991-09-27 Method of assaying endotoxin

Publications (2)

Publication Number Publication Date
DE69123445D1 DE69123445D1 (de) 1997-01-16
DE69123445T2 true DE69123445T2 (de) 1997-04-24

Family

ID=17306062

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69123445T Expired - Fee Related DE69123445T2 (de) 1990-09-28 1991-09-27 Verfahren zur bestimmung von endotoxinen

Country Status (6)

Country Link
US (1) US5378610A (de)
EP (1) EP0513361B1 (de)
JP (1) JP2957251B2 (de)
DE (1) DE69123445T2 (de)
ES (1) ES2094821T3 (de)
WO (1) WO1992006382A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2737514B2 (ja) * 1992-01-24 1998-04-08 和光純薬工業株式会社 エンドトキシン測定用試料の前処理方法
JP3524120B2 (ja) * 1992-05-08 2004-05-10 生化学工業株式会社 前処理剤、前処理方法、前処理された試料による測定法、測定用キット及び試料の判定方法
JP3242733B2 (ja) * 1993-02-26 2001-12-25 生化学工業株式会社 エンドトキシン特異的測定剤
JP3429036B2 (ja) * 1993-09-30 2003-07-22 生化学工業株式会社 エンドトキシンの特異的測定剤
WO1995014932A1 (fr) * 1993-11-22 1995-06-01 Seikagaku Corporation Procede de dosage d'une substance reagissant avec un reactif de limulus
US5648230A (en) * 1994-06-30 1997-07-15 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Endotoxin stabilizing agent, endotoxin composition and method for assaying endotoxin
US5855832A (en) * 1996-06-27 1999-01-05 Clausi; Robert N. Method of molding powdered plant fiber into high density materials
US6168924B1 (en) * 1996-10-21 2001-01-02 Seikagaku Kogyo Kabushiki Kaisha Limulus reaction-activating substance, method for inactivating the substance and measuring its amount, and method for measuring limulus reaction
WO2005024050A1 (en) * 2003-09-10 2005-03-17 Antibodyshop A/S Analytical methods for determination of proteolytic cleavage at specific sites
US7638340B2 (en) 2005-06-22 2009-12-29 Seikagu Corporation Method of eliminating reactivity of lipoarabinomannan and application of the same
CN104884952A (zh) * 2012-12-28 2015-09-02 生化学工业株式会社 付之鲎试验的抗凝血酶iii用的前处理剂及前处理方法
LT3124976T (lt) 2015-07-28 2018-12-27 F. Hoffmann-La Roche Ag Patobulintas bakterinio endotoksino testas, skirtas endotoksinų aptikimui
CN112462076B (zh) * 2020-11-12 2022-10-18 天津华龛生物科技有限公司 应用于微载体的内毒素含量的检测方法
CN112462015B (zh) * 2020-11-18 2022-07-12 海南倍特药业有限公司 一种氢溴酸瑞马唑仑细菌内毒素的检测方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4096091A (en) * 1974-07-17 1978-06-20 Baxter Travenol Laboratories, Inc. Limulus lysate having improved capacity to precipitate in the presence of low endotoxin concentrations, and reconstituting solutions therefor
US4221866A (en) * 1978-10-06 1980-09-09 Baxter Travenol Laboratories, Inc. Method for determining endotoxin concentration
US4276050A (en) * 1980-01-10 1981-06-30 Abbott Laboratories Method for systemic endotoxin detection
US4322217A (en) * 1980-06-27 1982-03-30 Mallinckrodt, Inc. Process for preparing Limulus lysate
BE889407A (fr) * 1980-06-27 1981-10-16 Mallinckrodt Inc Amelioration du procede de preparation d'un lysat de limule
US4406832A (en) * 1981-09-03 1983-09-27 Mallinckrodt, Inc. Peptide-type substrates useful in the quantitative determination of endotoxin
JPS5885162A (ja) * 1981-11-16 1983-05-21 Seikagaku Kogyo Co Ltd エンドトキシン測定法
US4808314A (en) * 1987-09-18 1989-02-28 Scripps Clinic And Research Foundation Method for reducing bacterial endotoxin contamination in solutions of macromolecules

Also Published As

Publication number Publication date
US5378610A (en) 1995-01-03
EP0513361B1 (de) 1996-12-04
WO1992006382A1 (en) 1992-04-16
DE69123445D1 (de) 1997-01-16
JPH04136763A (ja) 1992-05-11
EP0513361A1 (de) 1992-11-19
JP2957251B2 (ja) 1999-10-04
EP0513361A4 (de) 1992-07-21
ES2094821T3 (es) 1997-02-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee