LT3124976T - Patobulintas bakterinio endotoksino testas, skirtas endotoksinų aptikimui - Google Patents

Patobulintas bakterinio endotoksino testas, skirtas endotoksinų aptikimui

Info

Publication number
LT3124976T
LT3124976T LTEP15178683.7T LT15178683T LT3124976T LT 3124976 T LT3124976 T LT 3124976T LT 15178683 T LT15178683 T LT 15178683T LT 3124976 T LT3124976 T LT 3124976T
Authority
LT
Lithuania
Prior art keywords
endotoxins
determination
bacterial endotoxin
endotoxin test
improved bacterial
Prior art date
Application number
LTEP15178683.7T
Other languages
English (en)
Inventor
Sven Deutschmann
Pierre Lang
Friedrich VON WINTZINGERODE
Christian Alexander
Ulrich Zaehringer
Original Assignee
F. Hoffmann-La Roche Ag
Forschungszentrum Borstel, Leibniz Lungenzentrum
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag, Forschungszentrum Borstel, Leibniz Lungenzentrum filed Critical F. Hoffmann-La Roche Ag
Publication of LT3124976T publication Critical patent/LT3124976T/lt

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/579Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving limulus lysate
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38Diluting, dispersing or mixing samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2400/00Assays, e.g. immunoassays or enzyme assays, involving carbohydrates
    • G01N2400/10Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • G01N2400/50Lipopolysaccharides; LPS
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
LTEP15178683.7T 2015-07-28 2015-07-28 Patobulintas bakterinio endotoksino testas, skirtas endotoksinų aptikimui LT3124976T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP15178683.7A EP3124976B1 (en) 2015-07-28 2015-07-28 Improved bacterial endotoxin test for the determination of endotoxins

Publications (1)

Publication Number Publication Date
LT3124976T true LT3124976T (lt) 2018-12-27

Family

ID=53776384

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP15178683.7T LT3124976T (lt) 2015-07-28 2015-07-28 Patobulintas bakterinio endotoksino testas, skirtas endotoksinų aptikimui

Country Status (21)

Country Link
US (2) US10585097B2 (lt)
EP (1) EP3124976B1 (lt)
JP (2) JP6800226B2 (lt)
KR (1) KR102630300B1 (lt)
CN (2) CN108027374B (lt)
AR (1) AR105497A1 (lt)
AU (1) AU2016298598B2 (lt)
BR (1) BR112018001748A8 (lt)
CA (1) CA2989960C (lt)
DK (1) DK3124976T3 (lt)
ES (1) ES2699526T3 (lt)
HR (1) HRP20181954T1 (lt)
IL (2) IL256660B (lt)
LT (1) LT3124976T (lt)
MX (1) MX2018000679A (lt)
PL (1) PL3124976T3 (lt)
PT (1) PT3124976T (lt)
RS (1) RS58167B1 (lt)
SI (1) SI3124976T1 (lt)
TR (1) TR201816369T4 (lt)
WO (1) WO2017017135A1 (lt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11099189B2 (en) 2017-10-17 2021-08-24 Board Of Regents, The University Of Texas System Limulus amoebocyte lysate assay and method of same
EP3483609B1 (en) 2017-11-09 2022-01-05 Andreas Buchberger Method and kit for sample preparation and endotoxin determination
CN109613228A (zh) * 2018-12-20 2019-04-12 湛江安度斯生物有限公司 一种减少或消除氢氧化铝佐剂干扰细菌内毒素检测的方法
CN111141909B (zh) * 2019-12-24 2023-05-30 南京健友生化制药股份有限公司 一种凝胶法检测硫代甘油中细菌内毒素的方法
CN112462015B (zh) * 2020-11-18 2022-07-12 海南倍特药业有限公司 一种氢溴酸瑞马唑仑细菌内毒素的检测方法
CN116396916B (zh) * 2023-03-02 2023-12-01 广州普言生物科技有限公司 低内毒素大肠杆菌及低内毒素重组人源胶原蛋白大肠杆菌工程菌
CN117969228B (zh) * 2024-04-02 2024-05-28 成都翼泰生物科技有限公司 一种菌液稀释液、制备方法、参考品、试剂盒及其应用

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US4096091A (en) * 1974-07-17 1978-06-20 Baxter Travenol Laboratories, Inc. Limulus lysate having improved capacity to precipitate in the presence of low endotoxin concentrations, and reconstituting solutions therefor
JPS5549791Y2 (lt) * 1976-04-21 1980-11-20
DE3366540D1 (en) * 1982-04-28 1986-11-06 Trustees Of The Garfield Westo Processes for the production of blood products
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
DK255887D0 (da) * 1987-05-20 1987-05-20 Claus Koch Immunoassay
US5959177A (en) 1989-10-27 1999-09-28 The Scripps Research Institute Transgenic plants expressing assembled secretory antibodies
JP2957251B2 (ja) * 1990-09-28 1999-10-04 生化学工業株式会社 エンドトキシンの測定法
GB9021370D0 (en) * 1990-10-02 1990-11-14 Ciba Geigy Ag Monoclonal antibodies directed against complexes formed by thrombin and thrombin inhibitors
US7018809B1 (en) 1991-09-19 2006-03-28 Genentech, Inc. Expression of functional antibody fragments
JP2761839B2 (ja) * 1993-12-28 1998-06-04 株式会社 ソフィア 遊技機の表示制御装置
US5789199A (en) 1994-11-03 1998-08-04 Genentech, Inc. Process for bacterial production of polypeptides
US5840523A (en) 1995-03-01 1998-11-24 Genetech, Inc. Methods and compositions for secretion of heterologous polypeptides
JPH09171018A (ja) * 1995-12-19 1997-06-30 Tokuyama Corp 免疫学的凝集反応試薬の製造方法
EP0892271A1 (en) * 1997-07-14 1999-01-20 Universiteit Gent Laboratorium voor Bromatologie Faculteit Farmaceutische Wetenschappen Detection of mycotoxins by flow-through membrane-based enzyme immunoassay
US6040498A (en) 1998-08-11 2000-03-21 North Caroline State University Genetically engineered duckweed
JP2000105232A (ja) * 1998-09-29 2000-04-11 Sekisui Chem Co Ltd 抗HBs抗体測定試薬の製造方法
JP4310854B2 (ja) * 1999-06-14 2009-08-12 Jsr株式会社 診断薬用担体粒子および診断薬
PT1222292E (pt) 1999-10-04 2005-11-30 Medicago Inc Metodo para regulacao da transcricao de genes exogenos na presenca de azoto
US7125978B1 (en) 1999-10-04 2006-10-24 Medicago Inc. Promoter for regulating expression of foreign genes
AU2001296301A1 (en) * 2000-09-26 2002-04-08 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
US7303890B2 (en) 2000-09-27 2007-12-04 Japan Tobacco Inc. Proteins, genes encoding them and method of using the same
DE102005002969A1 (de) * 2005-01-21 2006-08-03 Profos Ag Verfahren zum Nachweis und zur Entfernung von Endotoxin
PE20140196A1 (es) 2007-08-09 2014-03-19 Boehringer Ingelheim Int Anticuerpos anti-cd37
WO2009063840A1 (ja) * 2007-11-12 2009-05-22 Hiroshima University エンドトキシンの濃度測定方法および濃度測定用キット
JP2008275638A (ja) * 2008-06-23 2008-11-13 Daicen Membrane Systems Ltd エンドトキシン濃度の簡易測定器
US7846678B2 (en) * 2008-08-18 2010-12-07 BioDtech, Inc. Enhancing endotoxin detection
AR078161A1 (es) 2009-09-11 2011-10-19 Hoffmann La Roche Formulaciones farmaceuticas muy concentradas de un anticuerpo anti cd20. uso de la formulacion. metodo de tratamiento.
CN102841205A (zh) 2011-07-19 2012-12-26 辽宁思百得医药科技有限公司 一种检测注射用氟罗沙星细菌内毒素的方法
EP2748609B1 (en) * 2011-09-01 2019-04-24 Fresenius Medical Care Holdings, Inc. Detection of endotoxin in aqueous solution
CN102901726B (zh) 2012-09-14 2014-08-13 莫水晶 血液细菌内毒素检测试剂盒的制备和应用

Also Published As

Publication number Publication date
TR201816369T4 (tr) 2018-11-21
DK3124976T3 (en) 2018-12-10
HRP20181954T1 (hr) 2019-01-25
US11360085B2 (en) 2022-06-14
WO2017017135A1 (en) 2017-02-02
JP7164790B2 (ja) 2022-11-02
KR20180030415A (ko) 2018-03-22
IL274576A (en) 2020-06-30
IL256660B (en) 2020-06-30
WO2017017135A8 (en) 2017-03-30
CA2989960A1 (en) 2017-02-02
IL274576B (en) 2021-05-31
JP2018529978A (ja) 2018-10-11
JP2021051080A (ja) 2021-04-01
US10585097B2 (en) 2020-03-10
BR112018001748A2 (pt) 2018-09-18
SI3124976T1 (sl) 2018-12-31
US20180188249A1 (en) 2018-07-05
PT3124976T (pt) 2018-11-20
CA2989960C (en) 2023-09-26
US20200240988A1 (en) 2020-07-30
AU2016298598A1 (en) 2018-01-18
EP3124976B1 (en) 2018-09-12
JP6800226B2 (ja) 2020-12-16
IL256660A (en) 2018-02-28
ES2699526T3 (es) 2019-02-11
CN108027374A (zh) 2018-05-11
RS58167B1 (sr) 2019-03-29
CN108027374B (zh) 2020-07-07
KR102630300B1 (ko) 2024-01-26
BR112018001748A8 (pt) 2023-04-25
EP3124976A1 (en) 2017-02-01
AR105497A1 (es) 2017-10-11
MX2018000679A (es) 2018-11-29
PL3124976T3 (pl) 2019-02-28
AU2016298598B2 (en) 2021-12-02
CN111638346A (zh) 2020-09-08

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