DE69122462D1 - 5-Amino-substituierte Adenosinanaloga als Immunsuppressiva - Google Patents

5-Amino-substituierte Adenosinanaloga als Immunsuppressiva

Info

Publication number
DE69122462D1
DE69122462D1 DE69122462T DE69122462T DE69122462D1 DE 69122462 D1 DE69122462 D1 DE 69122462D1 DE 69122462 T DE69122462 T DE 69122462T DE 69122462 T DE69122462 T DE 69122462T DE 69122462 D1 DE69122462 D1 DE 69122462D1
Authority
DE
Germany
Prior art keywords
immunosuppressants
amino substituted
substituted adenosine
adenosine analogues
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69122462T
Other languages
English (en)
Other versions
DE69122462T2 (de
Inventor
Terry L Bowlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Application granted granted Critical
Publication of DE69122462D1 publication Critical patent/DE69122462D1/de
Publication of DE69122462T2 publication Critical patent/DE69122462T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69122462T 1990-08-22 1991-08-21 5-Amino-substituierte Adenosinanaloga als Immunsuppressiva Expired - Fee Related DE69122462T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57104290A 1990-08-22 1990-08-22

Publications (2)

Publication Number Publication Date
DE69122462D1 true DE69122462D1 (de) 1996-11-07
DE69122462T2 DE69122462T2 (de) 1997-02-06

Family

ID=24282088

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69122462T Expired - Fee Related DE69122462T2 (de) 1990-08-22 1991-08-21 5-Amino-substituierte Adenosinanaloga als Immunsuppressiva

Country Status (11)

Country Link
EP (1) EP0472181B1 (de)
JP (1) JP3029065B2 (de)
KR (1) KR0169124B1 (de)
AT (1) ATE143600T1 (de)
AU (1) AU636053B2 (de)
DE (1) DE69122462T2 (de)
DK (1) DK0472181T3 (de)
ES (1) ES2094778T3 (de)
GR (1) GR3021727T3 (de)
IE (1) IE74220B1 (de)
ZA (1) ZA916464B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033590A1 (en) * 1996-03-13 1997-09-18 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
AU2022597A (en) * 1996-03-13 1997-10-01 Novo Nordisk A/S A method of treating disorders related to cytokines in mammals
US5747474A (en) * 1996-07-29 1998-05-05 Immune Modulation, Inc. Immunosuppression by administration of N6,N6 -disubstituted cAMP's, analogues thereof, and related nucleosides
US8633168B2 (en) 2007-06-15 2014-01-21 Genzyme Corporation Inhibitors of S-adenosyl-L-methionine decarboxylase
WO2013083813A2 (en) * 2011-12-07 2013-06-13 Universität Zürich Modulators of spermine/spermidine n'-acetyltransferase (ssat) and ssat associated proteins for use in prevention or treatment of rheumatoid arthritis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2387244A1 (fr) * 1977-04-13 1978-11-10 Anvar Derives amines de la 5'-deoxy-adenosine
US4794174A (en) * 1987-02-10 1988-12-27 Southern Research Institute 5'deoxy-5'-substituted adenosines
EP0358536B1 (de) * 1988-07-21 1996-05-08 Merrell Pharmaceuticals Inc. S'-adenosyl-methionin-decarboxylase-Inhibitoren
EP0351475A1 (de) * 1988-07-21 1990-01-24 Merrell Dow Pharmaceuticals Inc. S-Adenosylmethionin-decarboxylase-Inhibitoren

Also Published As

Publication number Publication date
ZA916464B (en) 1992-05-27
GR3021727T3 (en) 1997-02-28
DK0472181T3 (da) 1996-11-18
EP0472181B1 (de) 1996-10-02
EP0472181A3 (en) 1992-09-16
IE74220B1 (en) 1997-07-16
JPH04244095A (ja) 1992-09-01
KR920003976A (ko) 1992-03-27
ES2094778T3 (es) 1997-02-01
AU636053B2 (en) 1993-04-08
AU8251491A (en) 1992-02-27
DE69122462T2 (de) 1997-02-06
IE912963A1 (en) 1992-02-26
JP3029065B2 (ja) 2000-04-04
ATE143600T1 (de) 1996-10-15
EP0472181A2 (de) 1992-02-26
KR0169124B1 (ko) 1999-01-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee