DE69108139D1 - Verwendung von 5'-Vinylhalo-aristeromycin/adenosin-Analoga als Immunsuppressiva. - Google Patents

Verwendung von 5'-Vinylhalo-aristeromycin/adenosin-Analoga als Immunsuppressiva.

Info

Publication number
DE69108139D1
DE69108139D1 DE69108139T DE69108139T DE69108139D1 DE 69108139 D1 DE69108139 D1 DE 69108139D1 DE 69108139 T DE69108139 T DE 69108139T DE 69108139 T DE69108139 T DE 69108139T DE 69108139 D1 DE69108139 D1 DE 69108139D1
Authority
DE
Germany
Prior art keywords
vinylhalo
aristeromycin
immunosuppressants
adenosine analogues
adenosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69108139T
Other languages
English (en)
Other versions
DE69108139T2 (de
Inventor
Jeffrey A Wolos
Niall S Doherty
Esa T Jarvi
James R Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of DE69108139D1 publication Critical patent/DE69108139D1/de
Application granted granted Critical
Publication of DE69108139T2 publication Critical patent/DE69108139T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69108139T 1990-08-16 1991-08-16 Verwendung von 5'-Vinylhalo-aristeromycin/adenosin-Analoga als Immunsuppressiva. Expired - Fee Related DE69108139T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US56857990A 1990-08-16 1990-08-16

Publications (2)

Publication Number Publication Date
DE69108139D1 true DE69108139D1 (de) 1995-04-20
DE69108139T2 DE69108139T2 (de) 1995-07-06

Family

ID=24271855

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69108139T Expired - Fee Related DE69108139T2 (de) 1990-08-16 1991-08-16 Verwendung von 5'-Vinylhalo-aristeromycin/adenosin-Analoga als Immunsuppressiva.

Country Status (10)

Country Link
US (1) US5470837A (de)
EP (1) EP0471383B1 (de)
JP (1) JP3031573B2 (de)
KR (1) KR0169125B1 (de)
AT (1) ATE119779T1 (de)
AU (1) AU635857B2 (de)
DE (1) DE69108139T2 (de)
DK (1) DK0471383T3 (de)
IE (1) IE65567B1 (de)
ZA (1) ZA916350B (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0690068A4 (de) * 1993-03-18 1996-07-31 Akira Matsuda 2'-methyliden nukleotid-verbindungen, verfahren zu ihrer herstellung und ihre pharmazeutische verwendung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3472837A (en) * 1966-10-10 1969-10-14 Syntex Corp Unsaturated nucleosides and process for their preparation
US4997925A (en) * 1987-08-26 1991-03-05 Merrell Dow Pharmaceuticals Inc. 5'-deoxy-5',5'-dihalo adenosines and purine analogues
NZ225906A (en) * 1987-08-26 1990-10-26 Merrell Dow Pharma Aristeromycin/adenosine derivatives and pharmaceutical compositions
ZA907998B (en) * 1989-10-11 1991-07-31 Merrell Dow Pharma Inosine/guanosine derivatives as antineoplastic agents
ZA908001B (en) * 1989-10-11 1991-08-28 Merrell Dow Pharma Inosine/guanosine derivatives as immunosuppressive agents

Also Published As

Publication number Publication date
IE912897A1 (en) 1992-02-26
EP0471383B1 (de) 1995-03-15
EP0471383A2 (de) 1992-02-19
AU8243391A (en) 1992-02-20
US5470837A (en) 1995-11-28
EP0471383A3 (en) 1992-11-25
DK0471383T3 (da) 1995-05-22
KR920003975A (ko) 1992-03-27
AU635857B2 (en) 1993-04-01
IE65567B1 (en) 1995-11-01
ZA916350B (en) 1992-05-27
ATE119779T1 (de) 1995-04-15
JP3031573B2 (ja) 2000-04-10
DE69108139T2 (de) 1995-07-06
JPH04244027A (ja) 1992-09-01
KR0169125B1 (ko) 1999-01-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee