DE69121401T2 - Hemmung der abstossung bei allogener und concordanter xenogener transplantation - Google Patents

Hemmung der abstossung bei allogener und concordanter xenogener transplantation

Info

Publication number
DE69121401T2
DE69121401T2 DE69121401T DE69121401T DE69121401T2 DE 69121401 T2 DE69121401 T2 DE 69121401T2 DE 69121401 T DE69121401 T DE 69121401T DE 69121401 T DE69121401 T DE 69121401T DE 69121401 T2 DE69121401 T2 DE 69121401T2
Authority
DE
Germany
Prior art keywords
cyclosporin
survival
immunosuppressant
transplant
rejection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69121401T
Other languages
German (de)
English (en)
Other versions
DE69121401D1 (de
Inventor
Den Bogaerde Johan Beyers Van
David James Graham White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imutran Ltd
Original Assignee
Imutran Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imutran Ltd filed Critical Imutran Ltd
Application granted granted Critical
Publication of DE69121401D1 publication Critical patent/DE69121401D1/de
Publication of DE69121401T2 publication Critical patent/DE69121401T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13Cyclosporins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Transplantation (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69121401T 1990-04-09 1991-04-04 Hemmung der abstossung bei allogener und concordanter xenogener transplantation Expired - Fee Related DE69121401T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909007971A GB9007971D0 (en) 1990-04-09 1990-04-09 Pharmaceutical formulations
PCT/GB1991/000522 WO1991015221A1 (en) 1990-04-09 1991-04-04 Inhibition of allograft and concordant xenograft rejection

Publications (2)

Publication Number Publication Date
DE69121401D1 DE69121401D1 (de) 1996-09-19
DE69121401T2 true DE69121401T2 (de) 1996-12-12

Family

ID=10674123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69121401T Expired - Fee Related DE69121401T2 (de) 1990-04-09 1991-04-04 Hemmung der abstossung bei allogener und concordanter xenogener transplantation

Country Status (22)

Country Link
EP (1) EP0527762B1 (enExample)
JP (1) JP3518547B2 (enExample)
CN (1) CN1040178C (enExample)
AT (1) ATE141167T1 (enExample)
AU (1) AU7555591A (enExample)
CZ (1) CZ283119B6 (enExample)
DE (1) DE69121401T2 (enExample)
DK (1) DK0527762T3 (enExample)
ES (1) ES2090325T3 (enExample)
GB (1) GB9007971D0 (enExample)
GR (1) GR3021642T3 (enExample)
HK (1) HK48597A (enExample)
IE (1) IE911153A1 (enExample)
IL (1) IL97788A (enExample)
IN (1) IN173149B (enExample)
MY (1) MY106158A (enExample)
NZ (1) NZ237739A (enExample)
PT (1) PT97277B (enExample)
SG (1) SG47465A1 (enExample)
SK (1) SK279949B6 (enExample)
WO (1) WO1991015221A1 (enExample)
ZA (1) ZA912467B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001030379A2 (en) * 1999-10-27 2001-05-03 Alexandra Lucas Compositions and methods for preventing and treating transplant rejection
JP2004509171A (ja) 2000-09-29 2004-03-25 ゾーン、 ロバート ズィー. 炎症及び免疫反応の治療方法及びその組成物
NZ551308A (en) * 2004-05-14 2009-06-26 Alexion Pharma Inc Prolongation of survival of an allograft by inhibiting complement activity
US7285530B2 (en) 2004-10-21 2007-10-23 Viron Therapeutics, Inc. Use of SERP-1 as an antiplatelet agent
SI3028716T1 (sl) 2006-10-10 2021-01-29 Regenesance B.V. Komplementarna inhibicija za izboljšano regeneracijo živcev
US9447176B2 (en) * 2008-11-10 2016-09-20 Alexion Pharmaceuticals, Inc. Methods and compositions for treating complement-associated disorders
SI3011345T1 (sl) 2013-08-07 2017-12-29 Alexion Pharmaceuticals, Inc. Biomarkerski proteini za atipični hemolitični uremični sindrom (ahus)

Also Published As

Publication number Publication date
ES2090325T3 (es) 1996-10-16
SK279949B6 (sk) 1999-06-11
CZ283119B6 (cs) 1998-01-14
ATE141167T1 (de) 1996-08-15
JP3518547B2 (ja) 2004-04-12
JPH05507266A (ja) 1993-10-21
DK0527762T3 (da) 1996-09-02
GR3021642T3 (en) 1997-02-28
DE69121401D1 (de) 1996-09-19
IL97788A0 (en) 1992-06-21
EP0527762A1 (en) 1993-02-24
MY106158A (en) 1995-03-31
PT97277B (pt) 1998-08-31
SG47465A1 (en) 1998-04-17
AU7555591A (en) 1991-10-30
IE911153A1 (en) 1991-10-09
CN1056240A (zh) 1991-11-20
IL97788A (en) 1998-02-08
ZA912467B (en) 1992-12-30
IN173149B (enExample) 1994-02-19
NZ237739A (en) 1993-09-27
PT97277A (pt) 1992-01-31
GB9007971D0 (en) 1990-06-06
EP0527762B1 (en) 1996-08-14
HK48597A (en) 1997-04-25
CN1040178C (zh) 1998-10-14
CS9100988A2 (en) 1991-12-17
WO1991015221A1 (en) 1991-10-17

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: GROSSE, BOCKHORNI, SCHUMACHER, 81476 MUENCHEN

8339 Ceased/non-payment of the annual fee