ZA912467B - Inhibition of allograft and concordant xenograft rejection - Google Patents
Inhibition of allograft and concordant xenograft rejectionInfo
- Publication number
- ZA912467B ZA912467B ZA912467A ZA912467A ZA912467B ZA 912467 B ZA912467 B ZA 912467B ZA 912467 A ZA912467 A ZA 912467A ZA 912467 A ZA912467 A ZA 912467A ZA 912467 B ZA912467 B ZA 912467B
- Authority
- ZA
- South Africa
- Prior art keywords
- allograft
- inhibition
- xenograft rejection
- concordant xenograft
- concordant
- Prior art date
Links
- 230000005764 inhibitory process Effects 0.000 title 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 2
- 229930105110 Cyclosporin A Natural products 0.000 abstract 2
- 108010036949 Cyclosporine Proteins 0.000 abstract 2
- 229960001265 ciclosporin Drugs 0.000 abstract 2
- 210000002925 A-like Anatomy 0.000 abstract 1
- 101710172562 Cobra venom factor Proteins 0.000 abstract 1
- 229940124073 Complement inhibitor Drugs 0.000 abstract 1
- 239000004074 complement inhibitor Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229930182912 cyclosporin Natural products 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Marine Sciences & Fisheries (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Transplantation (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Plant Substances (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909007971A GB9007971D0 (en) | 1990-04-09 | 1990-04-09 | Pharmaceutical formulations |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA912467B true ZA912467B (en) | 1992-12-30 |
Family
ID=10674123
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA912467A ZA912467B (en) | 1990-04-09 | 1991-04-03 | Inhibition of allograft and concordant xenograft rejection |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0527762B1 (enExample) |
| JP (1) | JP3518547B2 (enExample) |
| CN (1) | CN1040178C (enExample) |
| AT (1) | ATE141167T1 (enExample) |
| AU (1) | AU7555591A (enExample) |
| CZ (1) | CZ283119B6 (enExample) |
| DE (1) | DE69121401T2 (enExample) |
| DK (1) | DK0527762T3 (enExample) |
| ES (1) | ES2090325T3 (enExample) |
| GB (1) | GB9007971D0 (enExample) |
| GR (1) | GR3021642T3 (enExample) |
| HK (1) | HK48597A (enExample) |
| IE (1) | IE911153A1 (enExample) |
| IL (1) | IL97788A (enExample) |
| IN (1) | IN173149B (enExample) |
| MY (1) | MY106158A (enExample) |
| NZ (1) | NZ237739A (enExample) |
| PT (1) | PT97277B (enExample) |
| SG (1) | SG47465A1 (enExample) |
| SK (1) | SK279949B6 (enExample) |
| WO (1) | WO1991015221A1 (enExample) |
| ZA (1) | ZA912467B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001030379A2 (en) * | 1999-10-27 | 2001-05-03 | Alexandra Lucas | Compositions and methods for preventing and treating transplant rejection |
| JP2004509171A (ja) | 2000-09-29 | 2004-03-25 | ゾーン、 ロバート ズィー． | 炎症及び免疫反応の治療方法及びその組成物 |
| NZ551308A (en) * | 2004-05-14 | 2009-06-26 | Alexion Pharma Inc | Prolongation of survival of an allograft by inhibiting complement activity |
| US7285530B2 (en) | 2004-10-21 | 2007-10-23 | Viron Therapeutics, Inc. | Use of SERP-1 as an antiplatelet agent |
| SI3028716T1 (sl) | 2006-10-10 | 2021-01-29 | Regenesance B.V. | Komplementarna inhibicija za izboljšano regeneracijo živcev |
| US9447176B2 (en) * | 2008-11-10 | 2016-09-20 | Alexion Pharmaceuticals, Inc. | Methods and compositions for treating complement-associated disorders |
| SI3011345T1 (sl) | 2013-08-07 | 2017-12-29 | Alexion Pharmaceuticals, Inc. | Biomarkerski proteini za atipični hemolitični uremični sindrom (ahus) |
-
1990
- 1990-04-09 GB GB909007971A patent/GB9007971D0/en active Pending
-
1991
- 1991-04-02 MY MYPI91000550A patent/MY106158A/en unknown
- 1991-04-03 ZA ZA912467A patent/ZA912467B/xx unknown
- 1991-04-03 IN IN265MA1991 patent/IN173149B/en unknown
- 1991-04-04 EP EP91907303A patent/EP0527762B1/en not_active Expired - Lifetime
- 1991-04-04 WO PCT/GB1991/000522 patent/WO1991015221A1/en not_active Ceased
- 1991-04-04 DE DE69121401T patent/DE69121401T2/de not_active Expired - Fee Related
- 1991-04-04 JP JP50651691A patent/JP3518547B2/ja not_active Expired - Fee Related
- 1991-04-04 ES ES91907303T patent/ES2090325T3/es not_active Expired - Lifetime
- 1991-04-04 AU AU75555/91A patent/AU7555591A/en not_active Abandoned
- 1991-04-04 SG SG1996001900A patent/SG47465A1/en unknown
- 1991-04-04 DK DK91907303.1T patent/DK0527762T3/da active
- 1991-04-04 AT AT91907303T patent/ATE141167T1/de not_active IP Right Cessation
- 1991-04-08 IE IE115391A patent/IE911153A1/en not_active IP Right Cessation
- 1991-04-08 NZ NZ237739A patent/NZ237739A/xx unknown
- 1991-04-08 PT PT97277A patent/PT97277B/pt not_active IP Right Cessation
- 1991-04-08 IL IL97788A patent/IL97788A/en not_active IP Right Cessation
- 1991-04-09 SK SK988-91A patent/SK279949B6/sk unknown
- 1991-04-09 CZ CS91988A patent/CZ283119B6/cs not_active IP Right Cessation
- 1991-04-09 CN CN91102859A patent/CN1040178C/zh not_active Expired - Fee Related
-
1996
- 1996-11-14 GR GR960403013T patent/GR3021642T3/el unknown
-
1997
- 1997-04-17 HK HK48597A patent/HK48597A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2090325T3 (es) | 1996-10-16 |
| SK279949B6 (sk) | 1999-06-11 |
| CZ283119B6 (cs) | 1998-01-14 |
| ATE141167T1 (de) | 1996-08-15 |
| DE69121401T2 (de) | 1996-12-12 |
| JP3518547B2 (ja) | 2004-04-12 |
| JPH05507266A (ja) | 1993-10-21 |
| DK0527762T3 (da) | 1996-09-02 |
| GR3021642T3 (en) | 1997-02-28 |
| DE69121401D1 (de) | 1996-09-19 |
| IL97788A0 (en) | 1992-06-21 |
| EP0527762A1 (en) | 1993-02-24 |
| MY106158A (en) | 1995-03-31 |
| PT97277B (pt) | 1998-08-31 |
| SG47465A1 (en) | 1998-04-17 |
| AU7555591A (en) | 1991-10-30 |
| IE911153A1 (en) | 1991-10-09 |
| CN1056240A (zh) | 1991-11-20 |
| IL97788A (en) | 1998-02-08 |
| IN173149B (enExample) | 1994-02-19 |
| NZ237739A (en) | 1993-09-27 |
| PT97277A (pt) | 1992-01-31 |
| GB9007971D0 (en) | 1990-06-06 |
| EP0527762B1 (en) | 1996-08-14 |
| HK48597A (en) | 1997-04-25 |
| CN1040178C (zh) | 1998-10-14 |
| CS9100988A2 (en) | 1991-12-17 |
| WO1991015221A1 (en) | 1991-10-17 |
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