DE69120058T2 - Verbesserte kapillarzonenelektrophorese und geräte zur durchführung des verfahrens - Google Patents
Verbesserte kapillarzonenelektrophorese und geräte zur durchführung des verfahrensInfo
- Publication number
- DE69120058T2 DE69120058T2 DE69120058T DE69120058T DE69120058T2 DE 69120058 T2 DE69120058 T2 DE 69120058T2 DE 69120058 T DE69120058 T DE 69120058T DE 69120058 T DE69120058 T DE 69120058T DE 69120058 T2 DE69120058 T2 DE 69120058T2
- Authority
- DE
- Germany
- Prior art keywords
- capillary
- zeta
- potential
- zone electrophoresis
- carrying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44752—Controlling the zeta potential, e.g. by wall coatings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/477,755 US5151164A (en) | 1990-02-09 | 1990-02-09 | Enhanced capillary zone electrophoresis and apparatus for performance thereof |
PCT/US1991/000721 WO1991012073A1 (en) | 1990-02-09 | 1991-02-07 | Enhanced capillary zone electrophoresis and apparatus for performance thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69120058D1 DE69120058D1 (de) | 1996-07-11 |
DE69120058T2 true DE69120058T2 (de) | 1997-01-30 |
Family
ID=23897232
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69120058T Expired - Fee Related DE69120058T2 (de) | 1990-02-09 | 1991-02-07 | Verbesserte kapillarzonenelektrophorese und geräte zur durchführung des verfahrens |
Country Status (7)
Country | Link |
---|---|
US (1) | US5151164A (de) |
EP (1) | EP0517733B1 (de) |
JP (1) | JPH05505463A (de) |
AT (1) | ATE138827T1 (de) |
CA (1) | CA2075625A1 (de) |
DE (1) | DE69120058T2 (de) |
WO (1) | WO1991012073A1 (de) |
Families Citing this family (41)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5180475A (en) * | 1991-09-04 | 1993-01-19 | Hewlett-Packard Company | System and method for controlling electroosmotic flow |
US5262031A (en) * | 1991-06-21 | 1993-11-16 | Hewlett-Packard Company | Electroosmotic flow control apparatus for capillary electrophoresis |
GB2264783A (en) * | 1992-02-24 | 1993-09-08 | Gen Electric Co Plc | Electrophoretic analysis method utilising wave effect |
US5240585A (en) * | 1992-07-14 | 1993-08-31 | Hewlett-Packard Company | Conductive bridge for external control of electroosmotic flow |
US5282942A (en) * | 1993-01-22 | 1994-02-01 | Beckman Instruments, Inc. | Methods and apparatus for separating and mobilizing solutes in a solute mixture |
US5320730A (en) * | 1993-01-22 | 1994-06-14 | The Penn State Research Foundation | Capillary electrophoresis apparatus with improved electroosmotic flow control |
US5358618A (en) * | 1993-01-22 | 1994-10-25 | The Penn State Research Foundation | Capillary electrophoresis apparatus with improved electroosmotic flow control |
US5415747A (en) * | 1993-08-16 | 1995-05-16 | Hewlett-Packard Company | Capillary electrophoresis using zwitterion-coated capillary tubes |
FR2710279B1 (fr) * | 1993-09-23 | 1995-11-24 | Armand Ajdari | Perfectionnements aux procédés et dispositifs de séparation des particules contenues dans un fluide. |
US5374834A (en) * | 1993-10-12 | 1994-12-20 | Massachusetts Institute Of Technology | Ionic liquid-channel charge-coupled device |
US5441613A (en) * | 1993-12-03 | 1995-08-15 | Dionex Corporation | Methods and apparatus for real-time monitoring, measurement and control of electroosmotic flow |
US5800692A (en) * | 1995-04-17 | 1998-09-01 | Mayo Foundation For Medical Education And Research | Preseparation processor for use in capillary electrophoresis |
US5573651A (en) * | 1995-04-17 | 1996-11-12 | The Dow Chemical Company | Apparatus and method for flow injection analysis |
US5716379A (en) * | 1995-08-17 | 1998-02-10 | Medtronic, Inc. | Cardiac assist device having muscle augmentation prior to defibrillation |
SE506461C2 (sv) * | 1996-01-19 | 1997-12-15 | Johan Roeraade | Förfarande för storleksfraktionering av molekyler med hög molekylvikt, med användande av elektroosmotiskt flöde i en kapillärtub |
FR2776072B1 (fr) * | 1998-03-11 | 2000-06-02 | Centre Nat Rech Scient | Perfectionnements aux dispositifs d'electrophorese multicapillaires du type a detection en sortie des capillaires |
US6890411B1 (en) * | 1998-06-11 | 2005-05-10 | Arizona Board Of Regents | Control of flow and materials for micro devices |
KR20000003558A (ko) | 1998-06-29 | 2000-01-15 | 김영환 | 펄스발생장치 |
US20040246650A1 (en) * | 1998-08-06 | 2004-12-09 | Grigorov Leonid N. | Highly conductive macromolecular materials and improved methods for making same |
US6764817B1 (en) * | 1999-04-20 | 2004-07-20 | Target Discovery, Inc. | Methods for conducting metabolic analyses |
US6818112B2 (en) * | 1999-04-20 | 2004-11-16 | Target Discovery, Inc. | Protein separation via multidimensional electrophoresis |
US6569305B1 (en) * | 1999-10-15 | 2003-05-27 | James Palmer | Method for injection and stacking of analytes in high-conductivity samples |
US7141152B2 (en) * | 2000-03-16 | 2006-11-28 | Le Febre David A | Analyte species separation system |
US6749735B1 (en) * | 2000-03-16 | 2004-06-15 | David Le Febre | Electromobility focusing controlled channel electrophoresis system |
CA2403296A1 (en) * | 2000-04-10 | 2001-10-18 | Benjamin F. Cravatt | Proteomic analysis using activity-based probe libraries |
US6805783B2 (en) * | 2000-12-13 | 2004-10-19 | Toyo Technologies, Inc. | Method for manipulating a solution using a ferroelectric electro-osmotic pump |
US20030127329A1 (en) * | 2001-06-04 | 2003-07-10 | Devoe Donald Lad | Field effect flow control apparatus for microfluidic networks |
US7147764B2 (en) * | 2003-03-28 | 2006-12-12 | Applera Corporation | Dual electrode injection of analyte into a capillary electrophoretic device |
US7282127B2 (en) * | 2004-04-13 | 2007-10-16 | East Carolina | Microcapillary devices using high dielectric constant materials and related methods |
US8366897B2 (en) * | 2006-10-04 | 2013-02-05 | National Institute Of Standards And Technology | Gradient elution electrophoresis and detectorless electrophoresis apparatus |
US8080144B2 (en) * | 2006-10-04 | 2011-12-20 | The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology | Gradient elution electrophoresis |
US20090288950A1 (en) * | 2008-05-20 | 2009-11-26 | Tihiro Ohkawa | Liquid electro-mechanical prime mover |
US8715475B2 (en) | 2008-11-04 | 2014-05-06 | Etat Francais Represente Par Le Delegue General Pour L'armement | Microfluidic device for separating, fractionating, or preconcentrating analytes contained in an electrolyte |
WO2011108540A1 (ja) | 2010-03-03 | 2011-09-09 | 国立大学法人大阪大学 | ヌクレオチドを識別する方法および装置、ならびにポリヌクレオチドのヌクレオチド配列を決定する方法および装置 |
US9535033B2 (en) | 2012-08-17 | 2017-01-03 | Quantum Biosystems Inc. | Sample analysis method |
JP6282036B2 (ja) | 2012-12-27 | 2018-02-21 | クオンタムバイオシステムズ株式会社 | 物質の移動速度の制御方法および制御装置 |
JP6183776B2 (ja) * | 2013-03-26 | 2017-08-23 | Tdk株式会社 | 電気泳動チップ |
EP3578987A1 (de) | 2013-09-18 | 2019-12-11 | Quantum Biosystems Inc. | Biomolekülsequenzierungsvorrichtungen, -systeme und -verfahren |
JP2015077652A (ja) | 2013-10-16 | 2015-04-23 | クオンタムバイオシステムズ株式会社 | ナノギャップ電極およびその製造方法 |
US10438811B1 (en) | 2014-04-15 | 2019-10-08 | Quantum Biosystems Inc. | Methods for forming nano-gap electrodes for use in nanosensors |
US10378565B2 (en) * | 2014-09-29 | 2019-08-13 | University Of Florida Research Foundation, Inc. | Electro-fluid transducers |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56137143A (en) * | 1980-03-27 | 1981-10-26 | Shimadzu Corp | Measuring device for electrophoresis |
US4898658A (en) * | 1987-11-25 | 1990-02-06 | Northeastern University | Integrated temperature control/alignment system for high performance capillary electrophoretic apparatus |
US4931328A (en) * | 1988-08-19 | 1990-06-05 | Hewlett-Packard Company | Capillary tube with reduced protein interactions and controllable electroosmotic flow |
US4859301A (en) * | 1988-08-30 | 1989-08-22 | Beckman Instruments, Inc. | Separation of zone formation from electroosmotic impulse in tubular electrophoretic systems |
-
1990
- 1990-02-09 US US07/477,755 patent/US5151164A/en not_active Expired - Lifetime
-
1991
- 1991-02-07 EP EP91904207A patent/EP0517733B1/de not_active Expired - Lifetime
- 1991-02-07 WO PCT/US1991/000721 patent/WO1991012073A1/en active IP Right Grant
- 1991-02-07 DE DE69120058T patent/DE69120058T2/de not_active Expired - Fee Related
- 1991-02-07 CA CA002075625A patent/CA2075625A1/en not_active Abandoned
- 1991-02-07 AT AT91904207T patent/ATE138827T1/de not_active IP Right Cessation
- 1991-02-07 JP JP91504511A patent/JPH05505463A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
JPH05505463A (ja) | 1993-08-12 |
EP0517733A4 (de) | 1992-10-07 |
EP0517733B1 (de) | 1996-06-05 |
DE69120058D1 (de) | 1996-07-11 |
CA2075625A1 (en) | 1991-08-10 |
WO1991012073A1 (en) | 1991-08-22 |
EP0517733A1 (de) | 1992-12-16 |
US5151164A (en) | 1992-09-29 |
ATE138827T1 (de) | 1996-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: AGILENT TECHNOLOGIES, INC. (N.D.GES.D.STAATES DELA |
|
8339 | Ceased/non-payment of the annual fee |