DE69118826D1 - Propenamidderivate, deren Polymere, Copolymere und deren Verwendung - Google Patents
Propenamidderivate, deren Polymere, Copolymere und deren VerwendungInfo
- Publication number
- DE69118826D1 DE69118826D1 DE69118826T DE69118826T DE69118826D1 DE 69118826 D1 DE69118826 D1 DE 69118826D1 DE 69118826 T DE69118826 T DE 69118826T DE 69118826 T DE69118826 T DE 69118826T DE 69118826 D1 DE69118826 D1 DE 69118826D1
- Authority
- DE
- Germany
- Prior art keywords
- copolymers
- polymers
- propenamide derivatives
- propenamide
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical class NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 title 1
- 229920001577 copolymer Polymers 0.000 title 1
- 229920000642 polymer Polymers 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0815—Tripeptides with the first amino acid being basic
- C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/75—Fibrinogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP32461190 | 1990-11-27 | ||
JP33479390 | 1990-11-30 | ||
JP33479290 | 1990-11-30 | ||
JP3066158A JPH04213308A (ja) | 1990-11-27 | 1991-03-29 | プロペンアミド誘導体とアニオン性単量体との共重合物およびその用途 |
JP3066157A JP2745342B2 (ja) | 1990-11-30 | 1991-03-29 | プロペンアミド誘導体、その重合物およびその用途 |
JP3066160A JP2745343B2 (ja) | 1990-11-30 | 1991-03-29 | プロペンアミド誘導体とカチオン性単量体との共重合物およびその用途 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69118826D1 true DE69118826D1 (de) | 1996-05-23 |
DE69118826T2 DE69118826T2 (de) | 1996-11-14 |
Family
ID=27551032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69118826T Expired - Fee Related DE69118826T2 (de) | 1990-11-27 | 1991-11-27 | Propenamidderivate, deren Polymere, Copolymere und deren Verwendung |
Country Status (3)
Country | Link |
---|---|
US (1) | US6046289A (de) |
EP (1) | EP0488258B1 (de) |
DE (1) | DE69118826T2 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
EP0584273B1 (de) * | 1991-05-03 | 1998-12-30 | The Rockefeller University | Endothelzell-Ligand für den Leukocyten CR3 erkennender Antikörper |
EP0587205A1 (de) * | 1992-07-23 | 1994-03-16 | Duphar International Research B.V | Kultursystem für verankeringsabhängige Zellen |
JP2001513120A (ja) * | 1997-02-11 | 2001-08-28 | ザ カウンシル オブ ザ クイーンズランド インスティチュート オブ メディカル リサーチ | ペプチドを含むポリマー |
BR9815882A (pt) | 1998-06-03 | 2002-09-17 | Gpi Nil Holding Inc | Sulfonamidas ligadas por n de ácido carboxìlicos n-heterocìclicos ouou de isósteros de ácidos carboxìlicos |
US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
KR100756591B1 (ko) * | 1998-12-03 | 2007-09-10 | 포라 가세이 고교 가부시키가이샤 | 신규 화합물, 당해 화합물로부터 제조된 중합체 및 당해 중합체를 포함하는 조성물 |
US7053043B1 (en) * | 1999-07-23 | 2006-05-30 | Yeda Research And Development Co.Ltd. | Pharmaceutical compositions comprising synthetic peptide copolymers and methods for preventing and treating GVHD and HVGD |
US6417189B1 (en) | 1999-11-12 | 2002-07-09 | Gpi Nil Holdings, Inc. | AZA compounds, pharmaceutical compositions and methods of use |
US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
DE60026568D1 (de) | 1999-12-21 | 2006-05-04 | Mgi Gp Inc | Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung |
CA2544223C (en) | 2003-11-05 | 2017-03-07 | Dana-Farber Cancer Institute, Inc. | Stabilized alpha helical peptides and uses thereof |
US9403869B2 (en) | 2006-03-31 | 2016-08-02 | Council Of Scientific And Industrial Research | α5β1 integrin binding RGD-lipopeptides with gene transfer activities |
CA2939778C (en) | 2007-01-31 | 2019-01-29 | Dana-Farber Cancer Institute, Inc. | Stabilized p53 peptides and uses thereof |
CN101730708B (zh) | 2007-03-28 | 2013-09-18 | 哈佛大学校长及研究员协会 | 缝合多肽 |
SG188096A1 (en) * | 2008-01-30 | 2013-03-28 | Geron Corp | Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells |
KR20110007600A (ko) * | 2008-01-30 | 2011-01-24 | 제론 코포레이션 | 세포배양 제품 및 스크리닝하는 방법 |
CN105400735A (zh) | 2008-01-30 | 2016-03-16 | 阿斯特利亚斯生物治疗股份公司 | 用于培养干细胞衍生的心肌细胞的合成表面 |
KR20100126361A (ko) | 2008-02-08 | 2010-12-01 | 에일러론 테라퓨틱스 인코포레이티드 | 치료용 펩티드유사 거대고리 |
US20110144303A1 (en) * | 2008-04-08 | 2011-06-16 | Aileron Therapeutics, Inc. | Biologically Active Peptidomimetic Macrocycles |
CN104961795A (zh) * | 2008-09-22 | 2015-10-07 | 爱勒让治疗公司 | 用于制备纯化的多肽组合物的方法 |
AU2010204648B2 (en) | 2009-01-14 | 2016-09-01 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
US20110183418A1 (en) * | 2009-07-29 | 2011-07-28 | Arthur Winston Martin | Peptide-Polymer Cell Culture Articles and Methods of Making |
CA2774973A1 (en) | 2009-09-22 | 2011-03-31 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
SI2603600T1 (sl) | 2010-08-13 | 2019-04-30 | Aileron Therapeutics, Inc. | Peptidomimetični makrocikli |
WO2013059525A1 (en) | 2011-10-18 | 2013-04-25 | Aileron Therapeutics, Inc. | Peptidomimetic macrocyles |
SG11201404648PA (en) | 2012-02-15 | 2014-09-26 | Aileron Therapeutics Inc | Peptidomimetic macrocycles |
CN108912211A (zh) | 2012-02-15 | 2018-11-30 | 爱勒让治疗公司 | 三唑交联的和硫醚交联的拟肽大环化合物 |
EP2914256B1 (de) | 2012-11-01 | 2019-07-31 | Aileron Therapeutics, Inc. | Disubstituierte aminosäuren und verfahren zur herstellung und verwendung davon |
BR112017005736A2 (pt) | 2014-09-24 | 2017-12-12 | Aileron Therapeutics Inc | macrociclos peptidomiméticos e formulações dos mesmos |
EP3197478A4 (de) | 2014-09-24 | 2018-05-30 | Aileron Therapeutics, Inc. | Peptidomimetische makrozyklen und verwendungen davon |
US10253067B2 (en) | 2015-03-20 | 2019-04-09 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
US10059741B2 (en) | 2015-07-01 | 2018-08-28 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles |
US10023613B2 (en) | 2015-09-10 | 2018-07-17 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles as modulators of MCL-1 |
US20210388142A1 (en) * | 2020-06-16 | 2021-12-16 | Johnson & Johnson Vision Care, Inc. | Amino acid-based polymerizable compounds and ophthalmic devices prepared therefrom |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CS173846B1 (de) * | 1974-04-23 | 1977-03-31 | ||
CS173849B1 (de) * | 1974-04-25 | 1977-03-31 | ||
US4578079A (en) * | 1982-08-04 | 1986-03-25 | La Jolla Cancer Research Foundation | Tetrapeptide |
EP0387975A1 (de) * | 1989-03-16 | 1990-09-19 | W.R. Grace & Co.-Conn. | Zellkulturträger, Zellschicht, Zellmasse und ihre Herstellung |
US5278063A (en) * | 1989-09-28 | 1994-01-11 | Board Of Regents The University Of Texas System | Chemical modification of promote animal cell adhesion on surfaces |
US5330911A (en) * | 1989-09-28 | 1994-07-19 | Board Of Regents, The University Of Texas System | Surfaces having desirable cell adhesive effects |
FR2655048A1 (fr) * | 1989-11-27 | 1991-05-31 | Inst Nat Sante Rech Med | Procede d'obtention de copolymeres bioactifs par greffage de motifs vinyliques et copolymeres greffes resultants. |
GB9213077D0 (en) * | 1992-06-19 | 1992-08-05 | Erba Carlo Spa | Polymerbound taxol derivatives |
-
1991
- 1991-11-27 DE DE69118826T patent/DE69118826T2/de not_active Expired - Fee Related
- 1991-11-27 EP EP91120332A patent/EP0488258B1/de not_active Expired - Lifetime
-
1994
- 1994-07-20 US US08/278,251 patent/US6046289A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DE69118826T2 (de) | 1996-11-14 |
EP0488258A3 (en) | 1993-05-05 |
EP0488258A2 (de) | 1992-06-03 |
US6046289A (en) | 2000-04-04 |
EP0488258B1 (de) | 1996-04-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: FUJIFILM CORP., TOKIO/TOKYO, JP |
|
8339 | Ceased/non-payment of the annual fee |