DE69114721D1 - Verfahren zur herstellung einer festen dosierungseinheit zur verzögerten freigabe. - Google Patents

Verfahren zur herstellung einer festen dosierungseinheit zur verzögerten freigabe.

Info

Publication number
DE69114721D1
DE69114721D1 DE69114721T DE69114721T DE69114721D1 DE 69114721 D1 DE69114721 D1 DE 69114721D1 DE 69114721 T DE69114721 T DE 69114721T DE 69114721 T DE69114721 T DE 69114721T DE 69114721 D1 DE69114721 D1 DE 69114721D1
Authority
DE
Germany
Prior art keywords
producing
delayed release
dosing unit
solid dosing
dosage units
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69114721T
Other languages
English (en)
Other versions
DE69114721T2 (de
Inventor
Per Lundberg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AstraZeneca AB
Original Assignee
Astra AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra AB filed Critical Astra AB
Application granted granted Critical
Publication of DE69114721D1 publication Critical patent/DE69114721D1/de
Publication of DE69114721T2 publication Critical patent/DE69114721T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Control Of Vending Devices And Auxiliary Devices For Vending Devices (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69114721T 1990-12-07 1991-12-03 Verfahren zur herstellung einer festen dosierungseinheit zur verzögerten freigabe. Expired - Lifetime DE69114721T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9003904A SE9003904D0 (sv) 1990-12-07 1990-12-07 Method for the manufacture of a pharmaceutical dosage form
PCT/SE1991/000813 WO1992010169A1 (en) 1990-12-07 1991-12-03 Method for the manufacture of a controlled release solid unit dosage form

Publications (2)

Publication Number Publication Date
DE69114721D1 true DE69114721D1 (de) 1995-12-21
DE69114721T2 DE69114721T2 (de) 1996-04-18

Family

ID=20381123

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69114721T Expired - Lifetime DE69114721T2 (de) 1990-12-07 1991-12-03 Verfahren zur herstellung einer festen dosierungseinheit zur verzögerten freigabe.

Country Status (20)

Country Link
US (1) US5419918A (de)
EP (1) EP0560822B1 (de)
JP (1) JP3239319B2 (de)
AT (1) ATE130188T1 (de)
AU (1) AU659114B2 (de)
CA (1) CA2097175A1 (de)
DE (1) DE69114721T2 (de)
DK (1) DK0560822T3 (de)
ES (1) ES2079689T3 (de)
FI (1) FI932552A (de)
GR (1) GR3018685T3 (de)
HU (1) HUT64212A (de)
IE (1) IE914229A1 (de)
IS (1) IS3789A7 (de)
NO (1) NO932054D0 (de)
PL (1) PL168605B1 (de)
PT (1) PT99721A (de)
SE (1) SE9003904D0 (de)
WO (1) WO1992010169A1 (de)
YU (1) YU182091A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE219933T1 (de) * 1992-09-18 2002-07-15 Yamanouchi Pharma Co Ltd Hydrogelzubereitung mit verzögerter freisetzung
JP3598049B2 (ja) * 1992-09-18 2004-12-08 山之内製薬株式会社 ハイドロゲル徐放性製剤
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
US5393765A (en) * 1993-12-13 1995-02-28 Hoffmann-La Roche Inc. Pharmaceutical compositions with constant erosion volume for zero order controlled release
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
JP2000034224A (ja) * 1998-05-11 2000-02-02 Freunt Ind Co Ltd 徐放性錠剤、その添加剤組成物及びそれらの製造方法
US6368625B1 (en) 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
US6214381B1 (en) 1998-09-08 2001-04-10 Effcon, Inc. Methazolamide composition and method of use
WO2003011256A1 (en) * 2001-07-30 2003-02-13 Sun Pharmaceutical Industries Limited Oral controlled release pharmaceutical composition of a prokinetic agent
US20030068375A1 (en) 2001-08-06 2003-04-10 Curtis Wright Pharmaceutical formulation containing gelling agent
US20040185093A1 (en) * 2003-03-18 2004-09-23 Szymczak Christopher E. Compositions containing sucralose
US20060062811A1 (en) * 2004-09-21 2006-03-23 Szymczak Christopher E Medicinal cooling emulsions
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
AU2014255434B2 (en) * 2013-04-16 2018-11-08 Murray And Poole Enterprises Limited Sustained-release formulations of colchicine and methods of using same
US9980946B1 (en) 2017-01-25 2018-05-29 Effcon Laboratories, Inc. Extended release methazolamide formulation
JP7426685B2 (ja) * 2018-06-14 2024-02-02 株式会社東洋新薬 錠剤

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4369172A (en) * 1981-12-18 1983-01-18 Forest Laboratories Inc. Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose
FR2525474A1 (fr) * 1982-04-26 1983-10-28 Roussel Uclaf Nouvelle forme pharmaceutique orale de clometacine
DE3469849D1 (en) * 1983-12-20 1988-04-21 Tosoh Corp Process for preventing agglomeration of powders
US4795327A (en) * 1984-03-26 1989-01-03 Forest Laboratories, Inc. Controlled release solid drug dosage forms based on mixtures of water soluble nonionic cellulose ethers and anionic surfactants
EP0294493A4 (de) * 1986-12-25 1989-07-24 Teysan Pharmaceuticals Co Ltd Langsamlösliches granulatkorn und daraus hergestelltes langwirkendes mischgranulat.
US4786503A (en) * 1987-04-06 1988-11-22 Alza Corporation Dosage form comprising parallel lamine
US4971805A (en) * 1987-12-23 1990-11-20 Teysan Pharmaceuticals Co., Ltd. Slow-releasing granules and long acting mixed granules comprising the same
US5024842A (en) * 1988-04-28 1991-06-18 Alza Corporation Annealed coats
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition

Also Published As

Publication number Publication date
HUT64212A (en) 1993-12-28
ATE130188T1 (de) 1995-12-15
JPH06503310A (ja) 1994-04-14
IS3789A7 (is) 1992-06-08
US5419918A (en) 1995-05-30
JP3239319B2 (ja) 2001-12-17
PL299376A1 (en) 1994-03-07
EP0560822A1 (de) 1993-09-22
AU659114B2 (en) 1995-05-11
EP0560822B1 (de) 1995-11-15
NO932054L (no) 1993-06-04
DE69114721T2 (de) 1996-04-18
CA2097175A1 (en) 1992-06-08
PL168605B1 (pl) 1996-03-29
HU9301672D0 (en) 1993-09-28
GR3018685T3 (en) 1996-04-30
FI932552A0 (fi) 1993-06-04
YU182091A (sh) 1994-04-05
SE9003904D0 (sv) 1990-12-07
AU8930991A (en) 1992-07-08
NO932054D0 (no) 1993-06-04
ES2079689T3 (es) 1996-01-16
FI932552A (fi) 1993-06-04
IE914229A1 (en) 1992-06-17
DK0560822T3 (da) 1996-03-11
WO1992010169A1 (en) 1992-06-25
PT99721A (pt) 1993-04-30

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Legal Events

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