DE69110740D1 - Im Dickdarm zerfallende, Polypeptide enthaltende orale Formulierungen. - Google Patents
Im Dickdarm zerfallende, Polypeptide enthaltende orale Formulierungen.Info
- Publication number
- DE69110740D1 DE69110740D1 DE69110740T DE69110740T DE69110740D1 DE 69110740 D1 DE69110740 D1 DE 69110740D1 DE 69110740 T DE69110740 T DE 69110740T DE 69110740 T DE69110740 T DE 69110740T DE 69110740 D1 DE69110740 D1 DE 69110740D1
- Authority
- DE
- Germany
- Prior art keywords
- disintegrating
- oral formulations
- containing polypeptides
- chitosan
- physiologically active
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP02107060 | 1990-04-23 | ||
JP3100304A JPH0813748B2 (ja) | 1990-04-23 | 1991-04-05 | 大腸崩壊性ポリペプチド系経口製剤 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69110740D1 true DE69110740D1 (de) | 1995-08-03 |
DE69110740T2 DE69110740T2 (de) | 1995-11-23 |
Family
ID=26441356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69110740T Expired - Fee Related DE69110740T2 (de) | 1990-04-23 | 1991-04-22 | Im Dickdarm zerfallende, Polypeptide enthaltende orale Formulierungen. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0454383B1 (de) |
JP (1) | JPH0813748B2 (de) |
KR (1) | KR100262202B1 (de) |
AT (1) | ATE124255T1 (de) |
CA (1) | CA2041044C (de) |
DE (1) | DE69110740T2 (de) |
DK (1) | DK0454383T3 (de) |
ES (1) | ES2075348T3 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH064531B2 (ja) * | 1990-06-04 | 1994-01-19 | アイセロ化学株式会社 | 大腸崩壊性硬質カプセル |
JP2773959B2 (ja) * | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
DK0667148T3 (da) * | 1992-11-06 | 2002-07-22 | Hisamitsu Pharmaceutical Co | Peroralt farmaceutisk præparat, der udløses i den nedre del af mavetarmkanalen |
CN1072964C (zh) * | 1994-04-22 | 2001-10-17 | 山之内制药株式会社 | 结肠特异性释药系统 |
JPH10513202A (ja) * | 1996-06-11 | 1998-12-15 | ゾナジェン,インコーポレイテッド | キトサン薬物送達システム |
US6248362B1 (en) * | 1997-03-26 | 2001-06-19 | Meiji Seika Kaisha, Ltd. | Large intestinal delivery composite |
FI20000780A (fi) * | 2000-04-03 | 2001-10-04 | Novasso Oy | Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi |
PT1615646E (pt) | 2003-04-08 | 2015-02-12 | Progenics Pharm Inc | Formulações farmacêuticas com metilnaltrexona |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
MX351611B (es) | 2007-03-29 | 2017-10-20 | Wyeth Llc | Formas de cristal de bromuro de (r)-n-metilnaltrexona y uso de las mismas. |
ES2570374T3 (es) | 2007-03-29 | 2016-05-18 | Progenics Pharm Inc | Antagonistas del receptor opioide periférico y usos de los mismos |
WO2009099411A1 (en) | 2008-02-06 | 2009-08-13 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
WO2010062261A1 (en) * | 2008-11-29 | 2010-06-03 | The Thailand Research Fund | System and method for preparing a controlled releas preparation |
JP5496616B2 (ja) * | 2009-11-18 | 2014-05-21 | フロイント産業株式会社 | 大腸ドラッグデリバリーシステム製剤 |
CN102552919B (zh) * | 2010-12-15 | 2018-03-27 | 上海安博生物医药股份有限公司 | 一种给药组合物及其制备和使用方法 |
WO2011084618A2 (en) * | 2009-12-16 | 2011-07-14 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
JP5102401B1 (ja) | 2012-03-30 | 2012-12-19 | 森下仁丹株式会社 | 大腸特異崩壊性カプセル |
ITUA20161937A1 (it) * | 2016-03-23 | 2017-09-23 | S I I T S R L Servizio Int Imballaggi Termosaldanti | Preparazione per il controllo del peso corporeo a base di chitosano e cellulosa |
CN115192537B (zh) * | 2022-07-27 | 2024-03-26 | 康普药业股份有限公司 | 一种甲磺酸萘莫司他组合物及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001034A1 (en) * | 1987-07-24 | 1989-02-09 | The Regents Of The University Of Michigan | Encapsulation of biological materials in semi-permeable membranes |
-
1991
- 1991-04-05 JP JP3100304A patent/JPH0813748B2/ja not_active Expired - Fee Related
- 1991-04-22 DE DE69110740T patent/DE69110740T2/de not_active Expired - Fee Related
- 1991-04-22 KR KR1019910006421A patent/KR100262202B1/ko not_active IP Right Cessation
- 1991-04-22 EP EP91303560A patent/EP0454383B1/de not_active Expired - Lifetime
- 1991-04-22 ES ES91303560T patent/ES2075348T3/es not_active Expired - Lifetime
- 1991-04-22 AT AT91303560T patent/ATE124255T1/de not_active IP Right Cessation
- 1991-04-22 DK DK91303560.6T patent/DK0454383T3/da active
- 1991-04-23 CA CA002041044A patent/CA2041044C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH0813748B2 (ja) | 1996-02-14 |
DK0454383T3 (da) | 1995-11-13 |
DE69110740T2 (de) | 1995-11-23 |
EP0454383B1 (de) | 1995-06-28 |
CA2041044C (en) | 1996-03-26 |
KR920005690A (ko) | 1992-04-03 |
KR100262202B1 (ko) | 2000-09-01 |
JPH04225922A (ja) | 1992-08-14 |
EP0454383A1 (de) | 1991-10-30 |
CA2041044A1 (en) | 1991-10-24 |
ATE124255T1 (de) | 1995-07-15 |
ES2075348T3 (es) | 1995-10-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |