ES2075348T3 - Formulacion oral de serie polipeptida, disociable en el intestino grueso. - Google Patents
Formulacion oral de serie polipeptida, disociable en el intestino grueso.Info
- Publication number
- ES2075348T3 ES2075348T3 ES91303560T ES91303560T ES2075348T3 ES 2075348 T3 ES2075348 T3 ES 2075348T3 ES 91303560 T ES91303560 T ES 91303560T ES 91303560 T ES91303560 T ES 91303560T ES 2075348 T3 ES2075348 T3 ES 2075348T3
- Authority
- ES
- Spain
- Prior art keywords
- dissociable
- large intestine
- oral formulation
- polypeptide
- chitosan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE OBTIENE UN MEDICAMENTO DE POLIPEPTIDO DISOCIADO DEL INTESTINO GRUESO FORMANDO UNA CAPA DE REVESTIMIENTO DE UN POLIMERO SOLUBLE EN UN LIQUIDO QUE TIENE UN PH DE AL MENOS 5 SOBRE LA SUPERFICIE DE UN MEDICAMENTO COMPUESTO DE UN QUITOSANO QUE CONTIENE UN POLIPEPTIDO FISIOLOGICAMENTE ACTIVO, UN MEDICAMENTO COMPUESTO FORMADO QUE REVISTE UN POLIPEPTIDO FISIOLOGICAMENTE ACTIVO CON QUITOSANO, O UN MEDICAMENTO COMPUESTO FORMADO QUE ENCAPSULA UN POLIPEPTIDO FISIOLOGICAMENTE ACTIVO CON UNA CAPSULA QUE CONTIENE QUITOSANO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP02107060 | 1990-04-23 | ||
JP3100304A JPH0813748B2 (ja) | 1990-04-23 | 1991-04-05 | 大腸崩壊性ポリペプチド系経口製剤 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2075348T3 true ES2075348T3 (es) | 1995-10-01 |
Family
ID=26441356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91303560T Expired - Lifetime ES2075348T3 (es) | 1990-04-23 | 1991-04-22 | Formulacion oral de serie polipeptida, disociable en el intestino grueso. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0454383B1 (es) |
JP (1) | JPH0813748B2 (es) |
KR (1) | KR100262202B1 (es) |
AT (1) | ATE124255T1 (es) |
CA (1) | CA2041044C (es) |
DE (1) | DE69110740T2 (es) |
DK (1) | DK0454383T3 (es) |
ES (1) | ES2075348T3 (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH064531B2 (ja) * | 1990-06-04 | 1994-01-19 | アイセロ化学株式会社 | 大腸崩壊性硬質カプセル |
JP2773959B2 (ja) * | 1990-07-10 | 1998-07-09 | 信越化学工業株式会社 | 大腸内放出性固形製剤 |
WO1994010983A1 (en) * | 1992-11-06 | 1994-05-26 | Hisamitsu Pharmaceutical Co., Inc. | Peroral pharmaceutical preparation releasable in lower digestive tract |
WO1995028963A1 (fr) * | 1994-04-22 | 1995-11-02 | Yamanouchi Pharmaceutical Co., Ltd. | Systeme de liberation de medicament specifique au colon |
AU3481497A (en) * | 1996-06-11 | 1998-01-07 | Zonagen, Inc. | Chitosan drug delivery system |
US6248362B1 (en) * | 1997-03-26 | 2001-06-19 | Meiji Seika Kaisha, Ltd. | Large intestinal delivery composite |
FI20000780A (fi) * | 2000-04-03 | 2001-10-04 | Novasso Oy | Peroraalinen lääkemuoto lääkeaineen hallituksi vapauttamiseksi |
DK2368553T3 (en) | 2003-04-08 | 2015-02-09 | Progenics Pharm Inc | Pharmaceutical preparation comprising methylnaltrexone |
AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
AR057035A1 (es) | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
EP3064503A1 (en) | 2007-03-29 | 2016-09-07 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
ES2765811T5 (es) | 2007-03-29 | 2024-02-27 | Progenics Pharm Inc | Forma cristalina de bromuro de (R)-n-metilnaltrexona y sus usos |
EP2240489A1 (en) | 2008-02-06 | 2010-10-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
WO2010062261A1 (en) * | 2008-11-29 | 2010-06-03 | The Thailand Research Fund | System and method for preparing a controlled releas preparation |
JP5496616B2 (ja) * | 2009-11-18 | 2014-05-21 | フロイント産業株式会社 | 大腸ドラッグデリバリーシステム製剤 |
CN102552919B (zh) * | 2010-12-15 | 2018-03-27 | 上海安博生物医药股份有限公司 | 一种给药组合物及其制备和使用方法 |
EP2512454A2 (en) * | 2009-12-16 | 2012-10-24 | Nod Pharmaceuticals, Inc. | Compositions and methods for oral drug delivery |
JP5102401B1 (ja) | 2012-03-30 | 2012-12-19 | 森下仁丹株式会社 | 大腸特異崩壊性カプセル |
ITUA20161937A1 (it) * | 2016-03-23 | 2017-09-23 | S I I T S R L Servizio Int Imballaggi Termosaldanti | Preparazione per il controllo del peso corporeo a base di chitosano e cellulosa |
CN115192537B (zh) * | 2022-07-27 | 2024-03-26 | 康普药业股份有限公司 | 一种甲磺酸萘莫司他组合物及其制备方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989001034A1 (en) * | 1987-07-24 | 1989-02-09 | The Regents Of The University Of Michigan | Encapsulation of biological materials in semi-permeable membranes |
-
1991
- 1991-04-05 JP JP3100304A patent/JPH0813748B2/ja not_active Expired - Fee Related
- 1991-04-22 EP EP91303560A patent/EP0454383B1/en not_active Expired - Lifetime
- 1991-04-22 DK DK91303560.6T patent/DK0454383T3/da active
- 1991-04-22 AT AT91303560T patent/ATE124255T1/de not_active IP Right Cessation
- 1991-04-22 KR KR1019910006421A patent/KR100262202B1/ko not_active IP Right Cessation
- 1991-04-22 ES ES91303560T patent/ES2075348T3/es not_active Expired - Lifetime
- 1991-04-22 DE DE69110740T patent/DE69110740T2/de not_active Expired - Fee Related
- 1991-04-23 CA CA002041044A patent/CA2041044C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0454383A1 (en) | 1991-10-30 |
CA2041044A1 (en) | 1991-10-24 |
EP0454383B1 (en) | 1995-06-28 |
DK0454383T3 (da) | 1995-11-13 |
DE69110740D1 (de) | 1995-08-03 |
CA2041044C (en) | 1996-03-26 |
JPH04225922A (ja) | 1992-08-14 |
KR100262202B1 (ko) | 2000-09-01 |
ATE124255T1 (de) | 1995-07-15 |
DE69110740T2 (de) | 1995-11-23 |
KR920005690A (ko) | 1992-04-03 |
JPH0813748B2 (ja) | 1996-02-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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