DE69030399T2 - Verfahren zur Herstellung von 3-Exomethylencephamsulfoxydderivate und Zwischenverbindungen - Google Patents

Verfahren zur Herstellung von 3-Exomethylencephamsulfoxydderivate und Zwischenverbindungen

Info

Publication number
DE69030399T2
DE69030399T2 DE69030399T DE69030399T DE69030399T2 DE 69030399 T2 DE69030399 T2 DE 69030399T2 DE 69030399 T DE69030399 T DE 69030399T DE 69030399 T DE69030399 T DE 69030399T DE 69030399 T2 DE69030399 T2 DE 69030399T2
Authority
DE
Germany
Prior art keywords
intermediates
preparation
sulfoxide derivatives
exomethylene cepham
cepham sulfoxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69030399T
Other languages
English (en)
Other versions
DE69030399D1 (de
Inventor
Jagdish Chander Kapur
Koning Jan Jacobus De
Roland Pieter Bezemer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke DSM NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of DE69030399D1 publication Critical patent/DE69030399D1/de
Application granted granted Critical
Publication of DE69030399T2 publication Critical patent/DE69030399T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
DE69030399T 1989-03-22 1990-03-21 Verfahren zur Herstellung von 3-Exomethylencephamsulfoxydderivate und Zwischenverbindungen Expired - Fee Related DE69030399T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89200718 1989-03-22

Publications (2)

Publication Number Publication Date
DE69030399D1 DE69030399D1 (de) 1997-05-15
DE69030399T2 true DE69030399T2 (de) 1997-10-16

Family

ID=8202345

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69030399T Expired - Fee Related DE69030399T2 (de) 1989-03-22 1990-03-21 Verfahren zur Herstellung von 3-Exomethylencephamsulfoxydderivate und Zwischenverbindungen

Country Status (12)

Country Link
US (1) US5053501A (de)
EP (1) EP0389064B1 (de)
JP (1) JPH0327354A (de)
KR (1) KR0157623B1 (de)
AT (1) ATE151428T1 (de)
DE (1) DE69030399T2 (de)
DK (1) DK0389064T3 (de)
ES (1) ES2102358T3 (de)
FI (1) FI103048B1 (de)
GR (1) GR3023523T3 (de)
HU (1) HU208540B (de)
PT (1) PT93529B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5347000A (en) * 1992-11-05 1994-09-13 Ranbaxy Laboratories Ltd. Process for the preparation of 2-chlorosulfinylazetidinone
US5604222A (en) 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1069126A (en) * 1974-12-24 1980-01-01 Eli Lilly And Company Sulfinyl halides and their preparation from penicillin sulfoxides
US4289695A (en) * 1978-11-13 1981-09-15 Eli Lilly And Company Process for preparing 2-chlorosulfinylazetidinones
US4190724A (en) * 1978-11-13 1980-02-26 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxides

Also Published As

Publication number Publication date
GR3023523T3 (en) 1997-08-29
HU901635D0 (en) 1990-06-28
ES2102358T3 (es) 1997-08-01
US5053501A (en) 1991-10-01
EP0389064A2 (de) 1990-09-26
DE69030399D1 (de) 1997-05-15
KR0157623B1 (ko) 1998-11-16
JPH0327354A (ja) 1991-02-05
ATE151428T1 (de) 1997-04-15
EP0389064A3 (de) 1992-01-22
FI901372A0 (fi) 1990-03-19
PT93529A (pt) 1990-11-07
PT93529B (pt) 1996-03-29
EP0389064B1 (de) 1997-04-09
HU208540B (en) 1993-11-29
DK0389064T3 (da) 1997-09-22
FI103048B (fi) 1999-04-15
KR900014404A (ko) 1990-10-23
HUT53652A (en) 1990-11-28
FI103048B1 (fi) 1999-04-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: DSM N.V., HEERLEN, NL

8339 Ceased/non-payment of the annual fee