ATE151428T1 - Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen - Google Patents

Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen

Info

Publication number
ATE151428T1
ATE151428T1 AT90200684T AT90200684T ATE151428T1 AT E151428 T1 ATE151428 T1 AT E151428T1 AT 90200684 T AT90200684 T AT 90200684T AT 90200684 T AT90200684 T AT 90200684T AT E151428 T1 ATE151428 T1 AT E151428T1
Authority
AT
Austria
Prior art keywords
derivatives
exomethylencephamsulfoxyde
producing
intermediate compounds
chlorosulfinylazetidin
Prior art date
Application number
AT90200684T
Other languages
English (en)
Inventor
Jagdish Chander Kapur
Koning Jan Jacobus De
Roland Pieter Bezemer
Original Assignee
Gist Brocades Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Nv filed Critical Gist Brocades Nv
Application granted granted Critical
Publication of ATE151428T1 publication Critical patent/ATE151428T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Pyrrole Compounds (AREA)
AT90200684T 1989-03-22 1990-03-21 Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen ATE151428T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89200718 1989-03-22

Publications (1)

Publication Number Publication Date
ATE151428T1 true ATE151428T1 (de) 1997-04-15

Family

ID=8202345

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90200684T ATE151428T1 (de) 1989-03-22 1990-03-21 Verfahren zur herstellung von 3- exomethylencephamsulfoxydderivate und zwischenverbindungen

Country Status (12)

Country Link
US (1) US5053501A (de)
EP (1) EP0389064B1 (de)
JP (1) JPH0327354A (de)
KR (1) KR0157623B1 (de)
AT (1) ATE151428T1 (de)
DE (1) DE69030399T2 (de)
DK (1) DK0389064T3 (de)
ES (1) ES2102358T3 (de)
FI (1) FI103048B1 (de)
GR (1) GR3023523T3 (de)
HU (1) HU208540B (de)
PT (1) PT93529B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5347000A (en) * 1992-11-05 1994-09-13 Ranbaxy Laboratories Ltd. Process for the preparation of 2-chlorosulfinylazetidinone
US5604222A (en) 1993-12-27 1997-02-18 Lupin Laboratories, Ltd. Method for the preparation of 2-chloro sulfinyl azetidinones
US5578721A (en) 1994-07-11 1996-11-26 Lupin Laboratories Limited Process for preparation of 3-exomethylene cepham sulfoxide esters

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1069126A (en) * 1974-12-24 1980-01-01 Eli Lilly And Company Sulfinyl halides and their preparation from penicillin sulfoxides
US4190724A (en) * 1978-11-13 1980-02-26 Eli Lilly And Company Process for 3-exomethylenecepham sulfoxides
US4289695A (en) * 1978-11-13 1981-09-15 Eli Lilly And Company Process for preparing 2-chlorosulfinylazetidinones

Also Published As

Publication number Publication date
EP0389064B1 (de) 1997-04-09
KR900014404A (ko) 1990-10-23
DE69030399D1 (de) 1997-05-15
KR0157623B1 (ko) 1998-11-16
HU901635D0 (en) 1990-06-28
PT93529A (pt) 1990-11-07
US5053501A (en) 1991-10-01
FI103048B (fi) 1999-04-15
EP0389064A3 (de) 1992-01-22
FI103048B1 (fi) 1999-04-15
HUT53652A (en) 1990-11-28
GR3023523T3 (en) 1997-08-29
JPH0327354A (ja) 1991-02-05
FI901372A0 (fi) 1990-03-19
DE69030399T2 (de) 1997-10-16
DK0389064T3 (da) 1997-09-22
EP0389064A2 (de) 1990-09-26
ES2102358T3 (es) 1997-08-01
HU208540B (en) 1993-11-29
PT93529B (pt) 1996-03-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee