DE69029625D1 - Verwendung von Retinoiden zur Umkehr glucocorticoid-induzierter Hautatrophie - Google Patents

Verwendung von Retinoiden zur Umkehr glucocorticoid-induzierter Hautatrophie

Info

Publication number
DE69029625D1
DE69029625D1 DE69029625T DE69029625T DE69029625D1 DE 69029625 D1 DE69029625 D1 DE 69029625D1 DE 69029625 T DE69029625 T DE 69029625T DE 69029625 T DE69029625 T DE 69029625T DE 69029625 D1 DE69029625 D1 DE 69029625D1
Authority
DE
Germany
Prior art keywords
retinoids
induced skin
skin atrophy
glucocorticoid
reverse
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029625T
Other languages
English (en)
Other versions
DE69029625T2 (de
Inventor
Albert M Kligman
James A Mezick
Robert J Capetola
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Application granted granted Critical
Publication of DE69029625D1 publication Critical patent/DE69029625D1/de
Publication of DE69029625T2 publication Critical patent/DE69029625T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Laminated Bodies (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Pens And Brushes (AREA)
DE69029625T 1989-08-31 1990-08-30 Verwendung von Retinoiden zur Umkehr glucocorticoid-induzierter Hautatrophie Expired - Lifetime DE69029625T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/401,362 US5019569A (en) 1986-11-03 1989-08-31 Reversal of glucocorticoid-induced skin atrophy

Publications (2)

Publication Number Publication Date
DE69029625D1 true DE69029625D1 (de) 1997-02-20
DE69029625T2 DE69029625T2 (de) 1997-05-28

Family

ID=23587438

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029625T Expired - Lifetime DE69029625T2 (de) 1989-08-31 1990-08-30 Verwendung von Retinoiden zur Umkehr glucocorticoid-induzierter Hautatrophie

Country Status (13)

Country Link
US (1) US5019569A (de)
EP (1) EP0415766B1 (de)
JP (1) JP3061628B2 (de)
AT (1) ATE147265T1 (de)
AU (1) AU634807B2 (de)
DE (1) DE69029625T2 (de)
DK (1) DK0415766T3 (de)
ES (1) ES2098253T3 (de)
GR (1) GR1000723B (de)
IE (1) IE903154A1 (de)
PT (1) PT95150B (de)
SG (1) SG50453A1 (de)
ZA (1) ZA906931B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5051449A (en) * 1991-02-27 1991-09-24 Kligman Albert M Treatment of cellulite with retinoids
US5254343A (en) * 1991-03-19 1993-10-19 Bristol-Myers Squibb Company Reduction of cutaneous atrophy
US5268176A (en) * 1991-07-22 1993-12-07 Avon Products, Inc. Method and compositions for the non-invasive treatment of telangiectasia
CZ188394A3 (en) * 1992-02-07 1996-02-14 Albert M Kligman Pharmaceutical preparation for the control of inflammatory dermatose cleaning and the use of corticosteroidal matter in combination with a retoidal matter for preparing such preparations
EP0659080B1 (de) * 1992-09-11 2001-07-11 BROWN, Sandra Verfahren zur behandlung von haarausfall
US6344448B1 (en) 1992-09-11 2002-02-05 Stb Family Limited Partnership Composition for the treatment of hair loss
CA2129773C (en) 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US6380255B1 (en) 1995-06-07 2002-04-30 Karo Bio Ab Treatment for dermal skin atrophy using thyroid hormone compounds or thyroid hormone-like compounds
US5837224A (en) * 1996-01-19 1998-11-17 The Regents Of The University Of Michigan Method of inhibiting photoaging of skin
UA48212C2 (uk) * 1996-01-31 2002-08-15 Сергей Дмітрієвіч БУРЛАКОВ Антиглюкокортикоїдний лікарський засіб
FR2760362B1 (fr) * 1997-03-10 2000-08-11 Vitasterol Utilisation cosmetique ou dermatologique de steroides 7-hydroxyles
US6008254A (en) 1997-05-09 1999-12-28 Kligman; Douglas E. Method of treating skin disorders with high-strength tretinoin
US8338648B2 (en) * 2004-06-12 2012-12-25 Signum Biosciences, Inc. Topical compositions and methods for epithelial-related conditions
NO326950B1 (no) * 2006-09-20 2009-03-16 Pharma Medico Res Ltd Kombinasjon av et glukokortikoid og et β-syklodekstrin konjugert vitamin A derivat-kompleks
US8809307B2 (en) 2010-11-22 2014-08-19 Dow Pharmaceutical Sciences, Inc. Pharmaceutical formulations containing corticosteroids for topical administration
US11957753B2 (en) 2010-11-22 2024-04-16 Bausch Health Ireland Limited Pharmaceutical formulations containing corticosteroids for topical administration
HUE050603T2 (hu) 2015-06-18 2020-12-28 Bausch Health Ireland Ltd Egy kortikoszteroidot és egy retinoidot tartalmazó topikális készítmények psoriasis kezelésére

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3729568A (en) * 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment
US4126693A (en) * 1975-11-03 1978-11-21 Johnson & Johnson Retinoic acid derivatives in the treatment of acne
US4487782A (en) * 1982-03-26 1984-12-11 Ortho Pharmaceutical Corporation Topical treatment of non-inflammatory acne
US4889847A (en) * 1986-11-03 1989-12-26 Ortho Pharmaceutical Corporation Prevention of glucocorticoid-induced skin atrophy
AU610587B2 (en) * 1987-04-06 1991-05-23 Daltex Medical Sciences, Inc. Treatment of aged skin with oral 13-cis-retinoic acid

Also Published As

Publication number Publication date
AU634807B2 (en) 1993-03-04
US5019569A (en) 1991-05-28
EP0415766A2 (de) 1991-03-06
ES2098253T3 (es) 1997-05-01
EP0415766A3 (en) 1992-04-08
JP3061628B2 (ja) 2000-07-10
ZA906931B (en) 1992-05-27
IE903154A1 (en) 1991-03-13
GR900100644A (en) 1991-12-30
SG50453A1 (en) 1998-07-20
DE69029625T2 (de) 1997-05-28
ATE147265T1 (de) 1997-01-15
AU6198790A (en) 1991-03-07
GR1000723B (el) 1992-11-23
EP0415766B1 (de) 1997-01-08
PT95150B (pt) 1997-06-30
JPH03141218A (ja) 1991-06-17
DK0415766T3 (da) 1997-01-27
PT95150A (pt) 1991-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN