DE69029138T2 - Neue bis-platinkomplexe als chemotherapeutisches mittel - Google Patents

Neue bis-platinkomplexe als chemotherapeutisches mittel

Info

Publication number
DE69029138T2
DE69029138T2 DE69029138T DE69029138T DE69029138T2 DE 69029138 T2 DE69029138 T2 DE 69029138T2 DE 69029138 T DE69029138 T DE 69029138T DE 69029138 T DE69029138 T DE 69029138T DE 69029138 T2 DE69029138 T2 DE 69029138T2
Authority
DE
Germany
Prior art keywords
platinum
sulfoxide
carboxylate
substituted
bis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69029138T
Other languages
English (en)
Other versions
DE69029138D1 (de
Inventor
Nicholas Farrell
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Vermont
Original Assignee
University of Vermont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Vermont filed Critical University of Vermont
Publication of DE69029138D1 publication Critical patent/DE69029138D1/de
Application granted granted Critical
Publication of DE69029138T2 publication Critical patent/DE69029138T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69029138T 1989-09-01 1990-09-04 Neue bis-platinkomplexe als chemotherapeutisches mittel Expired - Lifetime DE69029138T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/401,919 US5107007A (en) 1989-09-01 1989-09-01 Bis-platinum complexes as chemotherapeutic agents
PCT/US1990/004966 WO1991003482A1 (en) 1989-09-01 1990-09-04 New bis-platinum complexes as chemotherapeutic agents

Publications (2)

Publication Number Publication Date
DE69029138D1 DE69029138D1 (de) 1996-12-19
DE69029138T2 true DE69029138T2 (de) 1997-03-06

Family

ID=23589786

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029138T Expired - Lifetime DE69029138T2 (de) 1989-09-01 1990-09-04 Neue bis-platinkomplexe als chemotherapeutisches mittel

Country Status (9)

Country Link
US (1) US5107007A (de)
EP (1) EP0489850B1 (de)
JP (2) JP3142866B2 (de)
AT (1) ATE145210T1 (de)
AU (1) AU645266B2 (de)
CA (1) CA2065271C (de)
DE (1) DE69029138T2 (de)
ES (1) ES2094758T3 (de)
WO (1) WO1991003482A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206400A (en) * 1986-07-07 1993-04-27 Ohio State University Diastereomeric mono- and di-substituted diamino cyclohexane compounds and the method of preparation thereof
US5380897A (en) * 1993-05-25 1995-01-10 Hoeschele; James D. Tri(platinum) complexes
US5409915A (en) * 1993-09-14 1995-04-25 The University Of Vermont And State Agricultural College Bis-platinum (IV) complexes as chemotherapeutic agents
IT1273391B (it) * 1994-03-31 1997-07-08 Boehringer Mannheim Italia Platino complessi cationici trinucleari ad attivita' antitumorale e composizioni farmaceutiche che li contengono
AU2163797A (en) * 1996-03-11 1997-10-01 Debiopharm S.A. Binuclear platinum complexes, method for preparing same and pharmaceutical compositions containing said complexes
ZA976422B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polymethylene derivatives as ligands having antitumor activity.
ZA976421B (en) * 1996-07-22 1998-01-22 Boehringer Mannheim Italia New bis-platinum complexes with polyamine ligands as antitumor agents.
EP0870770A1 (de) * 1997-04-10 1998-10-14 Kreatech Biotechnology B.V. Trans-Platinverbindung, ein diese enthaltender, diagnostischer Kit, und ein Verfahren zur Markierung von bioorganischen Molekülen
EP0973785B1 (de) * 1997-04-10 2003-12-03 Kreatech Biotechnology B.V. Trans-platinverbindung und diagnostischer testsatz
SE9703396D0 (sv) * 1997-09-19 1997-09-19 Lincoln Binuclear complex
US6130245A (en) * 1998-10-26 2000-10-10 Unitech Pharmaceuticals, Inc. Dinuclear platinum complexes as cisplatin analogs for cancer treatment
US6001872A (en) * 1999-03-05 1999-12-14 Virginia Commonwealth University Water soluble transplatinum complexes with anti-cancer activity and method of using same
US6310047B1 (en) * 1999-08-24 2001-10-30 Virginia Commonwealth University High affinity DNA binding compounds as adjuvants in antisense technology
US7160908B2 (en) * 2003-03-04 2007-01-09 Unitech Pharmaceuticals, Inc. Dynamic anticancer platinum compounds
DE602006018299D1 (de) * 2005-06-30 2010-12-30 Bionumerik Pharmaceuticals Inc Platinanaloga mit monoazolligand
WO2007005056A2 (en) * 2005-06-30 2007-01-11 Bionumerik Pharmaceuticals, Inc. Platinum complexes with mononitrile-containing ligands
ITMI20052449A1 (it) * 2005-12-22 2007-06-23 Cell Therapeutics Europe Srl Nuovi bis-platino complessi ad attivita' antitumorale
WO2010005548A2 (en) * 2008-07-07 2010-01-14 Northwestern University Functionalization of carbon nanotubes with metallic moieties
US20100197890A1 (en) * 2009-01-31 2010-08-05 Mctavish Hugh Anti-cancer protein-platinum conjugates
WO2011085772A1 (en) 2010-01-15 2011-07-21 Basf Se "process for the dmc-catalyzed preparation of polyols"
WO2017110669A1 (ja) * 2015-12-22 2017-06-29 日本化薬株式会社 スルホキシド誘導体配位白金（ｉｉ）錯体の高分子結合体
KR102224578B1 (ko) * 2019-01-30 2021-03-05 전남대학교산학협력단 뱀장어를 비롯한 저서성 어류와 저서생물의 통합어도시스템

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4560782A (en) * 1982-11-19 1985-12-24 Research Corporation Anti-tumor diplatinum coordination compounds
US4533502A (en) * 1983-02-22 1985-08-06 Rochon Fernande D Platinum (II) compounds and their preparation
US4565884A (en) * 1983-05-10 1986-01-21 Andrulis Research Corporation Bis-platinum complexes as antitumor agents
DE3432320A1 (de) * 1984-09-03 1986-03-13 Behringwerke Ag, 3550 Marburg Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
US4797393A (en) * 1986-07-25 1989-01-10 University Of Vermont And State Agricultural College Bis-platinum complexes as chemotherapeutic agents
AU2817589A (en) * 1987-12-18 1989-07-19 Boehringer Biochemia Robin S.P.A Amino anthracenediones-bis platinum complexes, useful as antitumoral agents

Also Published As

Publication number Publication date
CA2065271C (en) 1996-02-20
AU645266B2 (en) 1994-01-13
EP0489850B1 (de) 1996-11-13
EP0489850A1 (de) 1992-06-17
JP3142866B2 (ja) 2001-03-07
ATE145210T1 (de) 1996-11-15
AU6405090A (en) 1991-04-08
WO1991003482A1 (en) 1991-03-21
JP3200421B2 (ja) 2001-08-20
CA2065271A1 (en) 1991-03-02
JP2000001496A (ja) 2000-01-07
ES2094758T3 (es) 1997-02-01
DE69029138D1 (de) 1996-12-19
JPH05500218A (ja) 1993-01-21
EP0489850A4 (en) 1992-11-04
US5107007A (en) 1992-04-21

Similar Documents

Publication Publication Date Title
DE69029138D1 (de) Neue bis-platinkomplexe als chemotherapeutisches mittel
Hutchinson et al. Metal isotope effect on metal-ligand vibrations. II. Tris complexes of 2, 2'-bipyridine and 1, 10-phenanthroline
US5288887B1 (en) Diamine platinum(iv) complexes having mixed carboxylate ligands as antitumor agents
SE8400865D0 (sv) Platinaforening samt forfarande for dess framstellning
NO178032C (no) Kaskadepolymerer, kontrastmiddel inneholdende slike, fremgangsmåte for fremstilling av kaskadepolymerene og anvendelse av disse
ATE248859T1 (de) Metallion-ligand koordinationskomplexe, antikorper dagegen und tests die solche antikorper verwenden
NO942231D0 (no) Heteroatomholdige ligander og metallkomplekser av disse
ZA878952B (en) Metal complex-containing pharmaceutical agents
DE3751967D1 (de) Bisplatinum-komplexe als chemotherapeutisches mittel
DE69014619D1 (de) Ruthenium(iii)-komplexe als antineoplastische mittel.
Harris et al. Oxygenation equilibriums of cobalt (II) complexes of amino acids and dipeptides
BR9403827A (pt) Composto, processo para sua preparação, e sua aplicação
ES2051253T1 (es) Procedimiento para la preparacion de complejos de metal con alta cifra de coordinacion y su aplicacion.
Mak et al. A polymeric silver (I) complex containing triply carboxylato-O, O′-bridged dinuclear cores,[{Ag4 (Me3NCH2CO2) 6} n](ClO4) 4n
DE69426118T2 (de) Tris(isonitril)kupfer(i)sulfate zur herstellung von radionukleidkomplexen
EP0409527A3 (en) Cis-diamineplatinum complexes with methanediphosphonate and substituted methanediphosphonate ligands as antitumor agents
Yadava et al. Coordination polymers of cobalt (II) involving 4, 4′-bipyridyl and its dioxide
DE3071968D1 (en) Denatured albumin complexes for radioscintigraphic imaging and evaluation of reticuloendothelial systems
Gaete et al. Iron (III) complexes with N-Methyl-4-mercaptopiperidine
DE3675859D1 (de) Platin(ii)-komplexe von 1,1-cyclo-butan-dicarboxylat, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
Xiao Binuclear Complexes of Rhodium and Iridium Bridged by Bis (diphenylphosphino) methane and 2-mercaptothiazolinate Ligands
Co We thank the SERC for an Award (to PBR) and Pro-getto Finalizzato Chimica Fine e Secondaria of National Research Council (C: NR-Italy).
ES280997U (es) Colgador para prendas de vestir, componible y con porta-accesorios

Legal Events

Date Code Title Description
8364 No opposition during term of opposition