DE69024154T2 - Pyrimidoindolderivate und Verfahren zu ihrer Herstellung - Google Patents
Pyrimidoindolderivate und Verfahren zu ihrer HerstellungInfo
- Publication number
- DE69024154T2 DE69024154T2 DE69024154T DE69024154T DE69024154T2 DE 69024154 T2 DE69024154 T2 DE 69024154T2 DE 69024154 T DE69024154 T DE 69024154T DE 69024154 T DE69024154 T DE 69024154T DE 69024154 T2 DE69024154 T2 DE 69024154T2
- Authority
- DE
- Germany
- Prior art keywords
- preparation
- alkyl
- pyrimidoindole derivatives
- pyrimidoindole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898921634A GB8921634D0 (en) | 1989-09-25 | 1989-09-25 | Pyrimidoindole derivatives and processes for preparation thereof |
GB909016704A GB9016704D0 (en) | 1990-07-30 | 1990-07-30 | Pyrimidoindole derivatives and processes for preparation thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69024154D1 DE69024154D1 (de) | 1996-01-25 |
DE69024154T2 true DE69024154T2 (de) | 1996-05-15 |
Family
ID=26295968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69024154T Expired - Fee Related DE69024154T2 (de) | 1989-09-25 | 1990-09-22 | Pyrimidoindolderivate und Verfahren zu ihrer Herstellung |
Country Status (7)
Country | Link |
---|---|
US (1) | US5180728A (de) |
EP (1) | EP0420086B1 (de) |
JP (1) | JP3079549B2 (de) |
KR (1) | KR0173451B1 (de) |
AT (1) | ATE131480T1 (de) |
CA (1) | CA2025820A1 (de) |
DE (1) | DE69024154T2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9026427D0 (en) * | 1990-12-05 | 1991-01-23 | Ici Plc | Chemical process |
EP0688216A1 (de) * | 1993-03-08 | 1995-12-27 | Fujisawa Pharmaceutical Co., Ltd. | Medikament zur behandlung und prävention von zerebrovaskulären erkrankungen |
CN113350356B (zh) * | 2021-05-26 | 2022-12-27 | 广东湛江海洋医药研究院 | 2,4,7-三取代嘧啶并吲哚化合物抗肿瘤耐药作用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4409224A (en) * | 1978-09-11 | 1983-10-11 | American Home Products Corp. | Pyrimido[1,6-a]indole derivatives |
US4695578A (en) * | 1984-01-25 | 1987-09-22 | Glaxo Group Limited | 1,2,3,9-tetrahydro-3-imidazol-1-ylmethyl-4H-carbazol-4-ones, composition containing them, and method of using them to treat neuronal 5HT function disturbances |
DE3687080T2 (de) * | 1985-04-27 | 1993-03-25 | Beecham Group Plc | Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung. |
EP0254584B1 (de) * | 1986-07-25 | 1992-10-07 | Beecham Group Plc | Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und ihre pharmazeutische Verwendung |
GB8623819D0 (en) * | 1986-10-03 | 1986-11-05 | Glaxo Group Ltd | Heterocyclic compounds |
GB8630071D0 (en) * | 1986-12-17 | 1987-01-28 | Glaxo Group Ltd | Medicaments |
IE61669B1 (en) * | 1987-09-03 | 1994-11-16 | Glaxo Group Ltd | Lactam derivatives |
-
1990
- 1990-08-27 US US07/572,247 patent/US5180728A/en not_active Expired - Fee Related
- 1990-08-30 KR KR1019900013457A patent/KR0173451B1/ko not_active IP Right Cessation
- 1990-09-20 CA CA002025820A patent/CA2025820A1/en not_active Abandoned
- 1990-09-21 JP JP02252743A patent/JP3079549B2/ja not_active Expired - Fee Related
- 1990-09-22 EP EP90118251A patent/EP0420086B1/de not_active Expired - Lifetime
- 1990-09-22 DE DE69024154T patent/DE69024154T2/de not_active Expired - Fee Related
- 1990-09-22 AT AT90118251T patent/ATE131480T1/de active
Also Published As
Publication number | Publication date |
---|---|
EP0420086A2 (de) | 1991-04-03 |
JPH03141281A (ja) | 1991-06-17 |
CA2025820A1 (en) | 1991-03-26 |
KR910006290A (ko) | 1991-04-29 |
ATE131480T1 (de) | 1995-12-15 |
EP0420086B1 (de) | 1995-12-13 |
KR0173451B1 (ko) | 1999-02-01 |
DE69024154D1 (de) | 1996-01-25 |
EP0420086A3 (en) | 1991-11-06 |
JP3079549B2 (ja) | 2000-08-21 |
US5180728A (en) | 1993-01-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |