DE69020804D1 - Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat. - Google Patents

Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat.

Info

Publication number
DE69020804D1
DE69020804D1 DE69020804T DE69020804T DE69020804D1 DE 69020804 D1 DE69020804 D1 DE 69020804D1 DE 69020804 T DE69020804 T DE 69020804T DE 69020804 T DE69020804 T DE 69020804T DE 69020804 D1 DE69020804 D1 DE 69020804D1
Authority
DE
Germany
Prior art keywords
preparation
acid dihydrate
tauroursodeoxycholic acid
acid
tauroursodeoxycholic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69020804T
Other languages
English (en)
Inventor
Massimo Parenti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prodotti Chimici e Alimentari SpA
Original Assignee
Prodotti Chimici e Alimentari SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prodotti Chimici e Alimentari SpA filed Critical Prodotti Chimici e Alimentari SpA
Application granted granted Critical
Publication of DE69020804D1 publication Critical patent/DE69020804D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
DE69020804T 1989-05-30 1990-03-05 Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat. Expired - Lifetime DE69020804D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8920698A IT1230796B (it) 1989-05-30 1989-05-30 Procedimento per la preparazione di acido tauroursodesossicolico biidrato.

Publications (1)

Publication Number Publication Date
DE69020804D1 true DE69020804D1 (de) 1995-08-17

Family

ID=11170729

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69020804T Expired - Lifetime DE69020804D1 (de) 1989-05-30 1990-03-05 Verfahren zur Herstellung von Tauroursodesoxycholsäure Dihydrat.

Country Status (5)

Country Link
EP (1) EP0400695B1 (de)
JP (1) JPH0317096A (de)
AT (1) ATE124954T1 (de)
DE (1) DE69020804D1 (de)
IT (1) IT1230796B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1247489B (it) * 1991-04-17 1994-12-17 Prodotti Chimici Alimentari Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
IT1255485B (it) * 1992-08-04 1995-11-06 Erregierre Ind Chim Processo per preparare gli acidi biliari coniugati con la glicina e relative composizioni terapeutiche per il trattamento dell'insufficienza epatica
US5616741A (en) * 1992-08-04 1997-04-01 Erregierre Industria Chimica S.P.A. Process for the preparation of glycine-conjugated bile acids
IT1255486B (it) * 1992-08-04 1995-11-06 Erregierre Ind Chim Processo per preparare gli acidi biliari coniugati con la taurina
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
KR100396113B1 (ko) * 1996-10-14 2003-12-24 동아제약 주식회사 타우로우르소데옥시콜린산의 정제방법
IT201900005906A1 (it) 2019-04-16 2020-10-16 Dipharma Francis Srl Procedimento di preparazione di coniugati di un acido colanico

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59159795A (ja) * 1983-03-04 1984-09-10 Yakult Honsha Co Ltd 微生物変換による抱合型ウルソデオキシコ−ル酸の製造方法
IT1167038B (it) * 1983-11-30 1987-05-06 Prodotti Chimici & Alimentari Procedimento per la sintesi di acido ursodesossicolico coniugato con la taurina
CH674369A5 (de) * 1986-11-26 1990-05-31 Jago Res Ag

Also Published As

Publication number Publication date
EP0400695B1 (de) 1995-07-12
JPH0317096A (ja) 1991-01-25
IT8920698A0 (it) 1989-05-30
IT1230796B (it) 1991-10-29
EP0400695A3 (de) 1991-07-24
ATE124954T1 (de) 1995-07-15
EP0400695A2 (de) 1990-12-05

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Legal Events

Date Code Title Description
8332 No legal effect for de