ATE124954T1 - Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat. - Google Patents
Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat.Info
- Publication number
- ATE124954T1 ATE124954T1 AT90200513T AT90200513T ATE124954T1 AT E124954 T1 ATE124954 T1 AT E124954T1 AT 90200513 T AT90200513 T AT 90200513T AT 90200513 T AT90200513 T AT 90200513T AT E124954 T1 ATE124954 T1 AT E124954T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- acid dihydrate
- tauroursodesoxycholic
- tauroursodesoxycholic acid
- acid
- Prior art date
Links
- -1 TAUROURSODESOXYCHOLIC ACID DIHYDRATE Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000002253 acid Substances 0.000 abstract 2
- XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 229960003080 taurine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
- C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8920698A IT1230796B (it) | 1989-05-30 | 1989-05-30 | Procedimento per la preparazione di acido tauroursodesossicolico biidrato. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE124954T1 true ATE124954T1 (de) | 1995-07-15 |
Family
ID=11170729
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90200513T ATE124954T1 (de) | 1989-05-30 | 1990-03-05 | Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0400695B1 (de) |
| JP (1) | JPH0317096A (de) |
| AT (1) | ATE124954T1 (de) |
| DE (1) | DE69020804D1 (de) |
| IT (1) | IT1230796B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1247489B (it) * | 1991-04-17 | 1994-12-17 | Prodotti Chimici Alimentari | Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono |
| US5616741A (en) * | 1992-08-04 | 1997-04-01 | Erregierre Industria Chimica S.P.A. | Process for the preparation of glycine-conjugated bile acids |
| IT1255485B (it) * | 1992-08-04 | 1995-11-06 | Erregierre Ind Chim | Processo per preparare gli acidi biliari coniugati con la glicina e relative composizioni terapeutiche per il trattamento dell'insufficienza epatica |
| IT1255486B (it) * | 1992-08-04 | 1995-11-06 | Erregierre Ind Chim | Processo per preparare gli acidi biliari coniugati con la taurina |
| IT1270853B (it) * | 1993-05-20 | 1997-05-13 | Sanofi Elf | Procedimento per la preparazione di derivati taurocolanici |
| KR100396113B1 (ko) * | 1996-10-14 | 2003-12-24 | 동아제약 주식회사 | 타우로우르소데옥시콜린산의 정제방법 |
| IT201900005906A1 (it) | 2019-04-16 | 2020-10-16 | Dipharma Francis Srl | Procedimento di preparazione di coniugati di un acido colanico |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS59159795A (ja) * | 1983-03-04 | 1984-09-10 | Yakult Honsha Co Ltd | 微生物変換による抱合型ウルソデオキシコ−ル酸の製造方法 |
| IT1167038B (it) * | 1983-11-30 | 1987-05-06 | Prodotti Chimici & Alimentari | Procedimento per la sintesi di acido ursodesossicolico coniugato con la taurina |
| CH674369A5 (de) * | 1986-11-26 | 1990-05-31 | Jago Res Ag |
-
1989
- 1989-05-30 IT IT8920698A patent/IT1230796B/it active
-
1990
- 1990-03-05 AT AT90200513T patent/ATE124954T1/de not_active IP Right Cessation
- 1990-03-05 DE DE69020804T patent/DE69020804D1/de not_active Expired - Lifetime
- 1990-03-05 EP EP90200513A patent/EP0400695B1/de not_active Expired - Lifetime
- 1990-05-10 JP JP2118862A patent/JPH0317096A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP0400695A3 (de) | 1991-07-24 |
| EP0400695A2 (de) | 1990-12-05 |
| JPH0317096A (ja) | 1991-01-25 |
| DE69020804D1 (de) | 1995-08-17 |
| IT1230796B (it) | 1991-10-29 |
| EP0400695B1 (de) | 1995-07-12 |
| IT8920698A0 (it) | 1989-05-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69413727D1 (de) | Verfahren zur Herstellung von Kohlenstoffdioxid-Absorptionsmittel durch Verwendung von Betonschlamm | |
| DE69318528D1 (de) | Zweistufiges von freien radikalen katalysiertes verfahren zur herstellung von alkenylbernsteinsäureanhydrid | |
| ATE39249T1 (de) | Verfahren zur herstellung von polyisocyanatopolyisocyanuraten durch katalytische cyclotrimerisierung von polyisocyanaten. | |
| DE3583209D1 (de) | Kontinuierliches verfahren zur herstellung von phosphorsaeure und von calciumsulfat. | |
| DE69011880D1 (de) | Verfahren zur Herstellung von L-Aminosäuren durch Fermentation. | |
| DE59003697D1 (de) | Verfahren zur Herstellung von Chromsäure. | |
| DE3854799D1 (de) | Verfahren zur Herstellung von veränderten Zeolithen | |
| DE3789557D1 (de) | Verfahren zur Herstellung von Maleimid. | |
| ATE124954T1 (de) | Verfahren zur herstellung von tauroursodesoxycholsäure dihydrat. | |
| DE59005939D1 (de) | Verfahren zur Herstellung von Oleum und Schwefelsäure. | |
| DE3776173D1 (de) | Verfahren zur herstellung von saeureamiden. | |
| DE3668164D1 (de) | Verfahren zur herstellung von tertiaeren olefinen durch zersetzung von alkyl-tert.-alkylaethern. | |
| DE69020081D1 (de) | Verfahren zur Herstellung von 3,3',4,4'-Biphenyltetracarbonsäure von hoher Reinheit oder deren Dianhydrid. | |
| AT384222B (de) | Verfahren zur herstellung von 7-amino-3alkoxymethyl-3-cephem-4-carbonsaeuren | |
| DE69008424D1 (de) | Verfahren zur Erzeugung von Nitrobenzolen. | |
| ATE127470T1 (de) | Verfahren zur herstellung von phosphatidylcholinderivaten. | |
| ATE92056T1 (de) | Verfahren zur herstellung von 5-chlor-3chlorsulfonyl-2-thiophencarbonsaeureestern. | |
| DE59205377D1 (de) | Mikrobiologisches Verfahren zur Herstellung von 5-Hydroxypyrazincarbonsäure | |
| DE3686968D1 (de) | Verfahren zur herstellung von tri-alkylbenzolsulfonaten des iminoctadine. | |
| DE69024999D1 (de) | Verfahren zur Herstellung von 2-Oxindol-1-carboxamiden | |
| ATE100789T1 (de) | Verfahren zur herstellung von saeureanhydriden. | |
| DE69002867D1 (de) | Verfahren zur Herstellung hochreiner o-Toluolsäure. | |
| DE59003699D1 (de) | Verfahren zur Herstellung von Chromsäure. | |
| ATE73125T1 (de) | Verfahren zur herstellung von dialkylaminoethylaminen. | |
| DE59008852D1 (de) | Verfahren zur Herstellung von 2-Acylamino-9-acyl-6-halogen-purinen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |