DE69013146D1 - Verfahren zur herstellung von 9-substituierten guaninderivaten und zwischenprodukte zur verwendung im verfahren. - Google Patents

Verfahren zur herstellung von 9-substituierten guaninderivaten und zwischenprodukte zur verwendung im verfahren.

Info

Publication number
DE69013146D1
DE69013146D1 DE69013146T DE69013146T DE69013146D1 DE 69013146 D1 DE69013146 D1 DE 69013146D1 DE 69013146 T DE69013146 T DE 69013146T DE 69013146 T DE69013146 T DE 69013146T DE 69013146 D1 DE69013146 D1 DE 69013146D1
Authority
DE
Germany
Prior art keywords
producing
intermediate products
substituted guanine
guanine derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69013146T
Other languages
English (en)
Other versions
DE69013146T2 (de
Inventor
Borge Alhede
Finn Clausen
Jorgen Juhl-Christensen
Klaus Mccluskey
Herbert Preikschat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hexal AS
Original Assignee
GEA Farmaceutisk Fabrik AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GEA Farmaceutisk Fabrik AS filed Critical GEA Farmaceutisk Fabrik AS
Application granted granted Critical
Publication of DE69013146D1 publication Critical patent/DE69013146D1/de
Publication of DE69013146T2 publication Critical patent/DE69013146T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
DE69013146T 1989-03-20 1990-03-19 Verfahren zur herstellung von 9-substituierten guaninderivaten und zwischenprodukte zur verwendung im verfahren. Expired - Fee Related DE69013146T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK135489A DK135489D0 (da) 1989-03-20 1989-03-20 Fremgangsmaade til fremstilling af 9-substituerede guaninderivater og mellemprodukter til brug ved fremgangsmaaden
PCT/DK1990/000077 WO1990011283A1 (en) 1989-03-20 1990-03-19 A process for the preparation of 9-substituted guanine derivatives and intermediates for use in the process

Publications (2)

Publication Number Publication Date
DE69013146D1 true DE69013146D1 (de) 1994-11-10
DE69013146T2 DE69013146T2 (de) 1995-02-16

Family

ID=8103930

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69013146T Expired - Fee Related DE69013146T2 (de) 1989-03-20 1990-03-19 Verfahren zur herstellung von 9-substituierten guaninderivaten und zwischenprodukte zur verwendung im verfahren.

Country Status (28)

Country Link
US (1) US5223619A (de)
EP (1) EP0464112B1 (de)
KR (1) KR0142098B1 (de)
AR (1) AR245719A1 (de)
AT (1) ATE112568T1 (de)
BG (1) BG60590B1 (de)
BR (1) BR9007230A (de)
CA (1) CA2047217A1 (de)
CS (1) CS9001365A3 (de)
DD (1) DD293116A5 (de)
DE (1) DE69013146T2 (de)
DK (2) DK135489D0 (de)
ES (1) ES2061023T3 (de)
FI (1) FI97387C (de)
GE (1) GEP19971014B (de)
GR (1) GR1001096B (de)
HR (1) HRP920907B1 (de)
HU (1) HU206715B (de)
IE (1) IE62042B1 (de)
LT (1) LT3183B (de)
LV (1) LV10455B (de)
NO (1) NO178497C (de)
PL (1) PL163313B1 (de)
RO (1) RO109737B1 (de)
RU (2) RU2090566C1 (de)
SI (1) SI9010545A (de)
WO (1) WO1990011283A1 (de)
YU (1) YU47343B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1264599B1 (it) * 1993-06-14 1996-10-04 Solar Chem Sa Processo per la sintesi della 9-(2-idrossietossimetil)- guanina
GB9520364D0 (en) * 1995-10-05 1995-12-06 Chiroscience Ltd Compouundds
US6860928B2 (en) 2002-09-04 2005-03-01 Xerox Corporation Alkylated urea and triaminotriazine compounds and phase change inks containing same
US6872243B2 (en) 2002-09-04 2005-03-29 Xerox Corporation Phase change inks containing gelator additives
US6761758B2 (en) 2002-09-04 2004-07-13 Xerox Corporation Alkylated tetrakis(triaminotriazine) compounds and phase change inks containing same
US6811595B2 (en) 2002-09-04 2004-11-02 Xerox Corporation Guanidinopyrimidinone compounds and phase change inks containing same
US7153349B2 (en) 2004-12-04 2006-12-26 Xerox Corporation Phase change inks containing curable trans-1,2-cyclohexane bis(urea-urethane) compounds
US7317122B2 (en) 2004-12-04 2008-01-08 Xerox Corporation Curable trans-1,2-cyclohexane bis(urea-urethane) compounds
US7220300B2 (en) 2004-12-04 2007-05-22 Xerox Corporation Phase change inks containing bis(urea-urethane) compounds
US7144450B2 (en) 2004-12-04 2006-12-05 Xerox Corporation Phase change inks containing trans-1,2-cyclohexane bis(urea-urethane) compounds
US7314949B2 (en) 2004-12-04 2008-01-01 Xerox Corporation Trans-1,2-cyclohexane bis(urea-urethane) compounds
US7560587B2 (en) 2004-12-04 2009-07-14 Xerox Corporation Bis[urea-urethane] compounds
WO2015062992A1 (en) 2013-10-29 2015-05-07 Swep International Ab A method of brazing a plate heat exchanger using screen printed brazing material; a plate heat exchanger manufactured by such method
CN115504977B (zh) * 2022-09-23 2024-02-09 海南锦瑞制药有限公司 更昔洛韦的制备方法及注射用更昔洛韦的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56152437U (de) * 1980-04-14 1981-11-14
US4451478A (en) * 1982-03-12 1984-05-29 Newport Pharmaceuticals International, Inc. Imidazole compounds
US4602089A (en) * 1982-03-12 1986-07-22 Newport Pharmaceuticals, Inc. Process for preparing purine compounds
JPS6055071B2 (ja) * 1982-04-16 1985-12-03 四国化成工業株式会社 イミダゾリル琥珀酸化合物および該化合物を用いるエポキシ樹脂硬化方法
HUT36464A (en) * 1983-05-24 1985-09-30 Newport Pharmaceuticals Process for producing erythro-4-amino-3-/2-hydroxy-3-alkyl/-imidazol-5-carboxamide
EP0219838A3 (de) * 1985-10-22 1988-04-06 Takeda Chemical Industries, Ltd. Carbocyclische Purin-Nukleoside, ihre Herstellung und Verwendung
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds

Also Published As

Publication number Publication date
BG60590B1 (en) 1995-09-29
GR1001096B (el) 1993-04-28
HRP920907B1 (en) 1998-06-30
DK0464112T3 (da) 1995-03-13
ES2061023T3 (es) 1994-12-01
NO178497C (no) 1996-04-10
SI9010545A (en) 1997-08-31
HRP920907A2 (hr) 1994-04-30
HU206715B (en) 1992-12-28
BR9007230A (pt) 1992-02-25
EP0464112A1 (de) 1992-01-08
DE69013146T2 (de) 1995-02-16
LV10455B (en) 1995-08-20
KR920701208A (ko) 1992-08-11
CA2047217A1 (en) 1990-09-21
GR900100212A (en) 1990-07-31
GEP19971014B (en) 1997-04-18
KR0142098B1 (ko) 1998-06-01
RU2042668C1 (ru) 1995-08-27
AR245719A1 (es) 1994-02-28
HU902874D0 (en) 1991-12-30
FI914418A0 (fi) 1991-09-19
PL163313B1 (pl) 1994-03-31
WO1990011283A1 (en) 1990-10-04
LV10455A (lv) 1995-02-20
IE62042B1 (en) 1994-12-14
NO913686D0 (no) 1991-09-19
NO178497B (no) 1996-01-02
LTIP297A (en) 1994-08-25
FI97387C (fi) 1996-12-10
CS275359B2 (en) 1992-02-19
ATE112568T1 (de) 1994-10-15
EP0464112B1 (de) 1994-10-05
YU54590A (sh) 1992-12-21
FI97387B (fi) 1996-08-30
NO913686L (no) 1991-09-19
RO109737B1 (ro) 1995-05-30
US5223619A (en) 1993-06-29
HUT59141A (en) 1992-04-28
CS9001365A3 (en) 1992-02-19
IE900994L (en) 1990-09-20
RU2090566C1 (ru) 1997-09-20
DK135489D0 (da) 1989-03-20
YU47343B (sh) 1995-01-31
DD293116A5 (de) 1991-08-22
LT3183B (en) 1995-03-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee