DE69009510D1 - Küvette für eine Polymerase-Reaktion und ihre Verwendung. - Google Patents

Küvette für eine Polymerase-Reaktion und ihre Verwendung.

Info

Publication number
DE69009510D1
DE69009510D1 DE69009510T DE69009510T DE69009510D1 DE 69009510 D1 DE69009510 D1 DE 69009510D1 DE 69009510 T DE69009510 T DE 69009510T DE 69009510 T DE69009510 T DE 69009510T DE 69009510 D1 DE69009510 D1 DE 69009510D1
Authority
DE
Germany
Prior art keywords
cell
polymerase reaction
polymerase
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69009510T
Other languages
English (en)
Other versions
DE69009510T2 (de
Inventor
Paul N Schnipelsky
Leonard J Seaberg
Jeffrey A Wellman
Charles C Hinckley
William H Donish
John B Findlay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Clinical Diagnostics Inc
Original Assignee
Eastman Kodak Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Kodak Co filed Critical Eastman Kodak Co
Application granted granted Critical
Publication of DE69009510D1 publication Critical patent/DE69009510D1/de
Publication of DE69009510T2 publication Critical patent/DE69009510T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/069—Absorbents; Gels to retain a fluid
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0478—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure pistons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE69009510T 1989-02-03 1990-02-01 Küvette für eine Polymerase-Reaktion und ihre Verwendung. Expired - Fee Related DE69009510T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30673589A 1989-02-03 1989-02-03
US33992389A 1989-04-17 1989-04-17

Publications (2)

Publication Number Publication Date
DE69009510D1 true DE69009510D1 (de) 1994-07-14
DE69009510T2 DE69009510T2 (de) 1995-01-05

Family

ID=26975330

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69009510T Expired - Fee Related DE69009510T2 (de) 1989-02-03 1990-02-01 Küvette für eine Polymerase-Reaktion und ihre Verwendung.

Country Status (7)

Country Link
EP (1) EP0381501B1 (de)
JP (1) JP2536945B2 (de)
KR (2) KR0161276B1 (de)
CA (1) CA1338505C (de)
DE (1) DE69009510T2 (de)
DK (1) DK0381501T3 (de)
FI (1) FI94360C (de)

Families Citing this family (103)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5714380A (en) * 1986-10-23 1998-02-03 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
ES2141088T3 (es) * 1990-02-16 2000-03-16 Hoffmann La Roche Mejoras en la especificidad y conveniencia de la reaccion en cadena de la polimerasa.
US5173260A (en) * 1990-09-17 1992-12-22 Eastman Kodak Company Beads fused to a test device support
US5154888A (en) * 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
US5133938A (en) * 1990-10-25 1992-07-28 Eastman Kodak Company Lockable valve mechanism for sample pouch
FR2669347A1 (fr) * 1990-11-15 1992-05-22 Inst Nat Sante Rech Med Procede permettant d'effectuer au moins deux reactions successives, en evitant les risques de contamination, notamment applicable aux techniques d'amplification de l'adn ou de l'arn.
FR2672301A1 (fr) * 1991-02-01 1992-08-07 Larzul Daniel Procede et dispositif pour amplifier le nombre d'une sequence definie d'acide nucleique dans un echantillon biologique.
US5258314A (en) * 1991-03-18 1993-11-02 Paradigm Biotechnologies Partnership Microprocessor-based biomedical monitoring apparatus and method
EP0504772A3 (en) * 1991-03-18 1993-01-27 Paradigm Biotechnologies Partnership Analytical apparatus
FR2674253B1 (fr) * 1991-03-19 1995-10-20 Diagnostics Pasteur Composition lyophilisee pour la multiplication de sequences d'acides nucleiques.
US5380489A (en) * 1992-02-18 1995-01-10 Eastman Kodak Company Element and method for nucleic acid amplification and detection using adhered probes
US7297313B1 (en) 1991-08-31 2007-11-20 The Regents Of The University Of California Microfabricated reactor, process for manufacturing the reactor, and method of amplification
FI915731A0 (fi) * 1991-12-05 1991-12-05 Derek Henry Potter Foerfarande och anordning foer reglering av temperaturen i ett flertal prov.
US5254479A (en) * 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
WO1993015222A1 (fr) * 1992-01-29 1993-08-05 Institut National De La Sante Et De La Recherche Medicale (Inserm) Procede pour eviter les risques de contamination, notamment applicable aux techniques d'amplification de l'adn ou de l'arn
DE4234086A1 (de) * 1992-02-05 1993-08-12 Diagen Inst Molekularbio Verfahren zur bestimmung von in vitro amplifizierten nukleinsaeuresequenzen
US5888723A (en) * 1992-02-18 1999-03-30 Johnson & Johnson Clinical Diagnostics, Inc. Method for nucleic acid amplification and detection using adhered probes
WO1993017328A1 (en) * 1992-02-20 1993-09-02 Drew Scientific Limited Liquid chromatography apparatus
WO1993022020A2 (en) * 1992-04-23 1993-11-11 Amoco Corporation Closed vessel for isolating target molecules and for performing amplification
US5364591A (en) * 1992-06-01 1994-11-15 Eastman Kodak Company Device for moving a target-bearing solid through a liquid for detection while being contained
US5290518A (en) * 1992-08-17 1994-03-01 Eastman Kodak Company Flexible extraction device with burstable sidewall
US5639423A (en) * 1992-08-31 1997-06-17 The Regents Of The University Of Calfornia Microfabricated reactor
US5565339A (en) * 1992-10-08 1996-10-15 Hoffmann-La Roche Inc. Compositions and methods for inhibiting dimerization of primers during storage of polymerase chain reaction reagents
US5288463A (en) * 1992-10-23 1994-02-22 Eastman Kodak Company Positive flow control in an unvented container
DE69305046T2 (de) * 1992-10-23 1997-04-03 Johnson & Johnson Clin Diag Regelung des Durchflusses in einem eingeschlossenen Behälter
TW313588B (de) * 1992-10-23 1997-08-21 Eastman Kodak Co
US5422271A (en) * 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
US5425917A (en) * 1992-11-09 1995-06-20 Schmid; Peter Apparatus for attaching a labeled probe and/or antibody to macromolecules
WO1994026414A1 (en) * 1993-05-17 1994-11-24 Syntex (U.S.A.) Inc. Reaction container for specific binding assays and method for its use
ATE170001T1 (de) * 1993-10-21 1998-09-15 Abbott Lab Vorrichtung und verfahren zur überführung einer probe eines fluids
US5645801A (en) * 1993-10-21 1997-07-08 Abbott Laboratories Device and method for amplifying and detecting target nucleic acids
US5415839A (en) * 1993-10-21 1995-05-16 Abbott Laboratories Apparatus and method for amplifying and detecting target nucleic acids
ATE193465T1 (de) * 1994-01-06 2000-06-15 Johnson & Johnson Clin Diag Vorrichtung zum erwärmen einer flüssigkeitsführenden kammer von einer reaktionscuvette
CA2143365A1 (en) * 1994-03-14 1995-09-15 Hugh V. Cottingham Nucleic acid amplification method and apparatus
US5725831A (en) * 1994-03-14 1998-03-10 Becton Dickinson And Company Nucleic acid amplification apparatus
DE4420732A1 (de) * 1994-06-15 1995-12-21 Boehringer Mannheim Gmbh Vorrichtung zur Behandlung von Nukleinsäuren aus einer Probe
US5605796A (en) * 1994-07-19 1997-02-25 Behringwerke Ag Method for preventing amplification of nucleic acid contaminants in amplification mixtures using nuclease-receptor conjugates
WO1997000442A1 (en) * 1995-06-16 1997-01-03 The University Of Washington Microfabricated differential extraction device and method
US5716852A (en) * 1996-03-29 1998-02-10 University Of Washington Microfabricated diffusion-based chemical sensor
US6454945B1 (en) 1995-06-16 2002-09-24 University Of Washington Microfabricated devices and methods
US6541213B1 (en) 1996-03-29 2003-04-01 University Of Washington Microscale diffusion immunoassay
US5948684A (en) 1997-03-31 1999-09-07 University Of Washington Simultaneous analyte determination and reference balancing in reference T-sensor devices
AU3570797A (en) 1996-06-14 1998-01-07 University Of Washington Absorption-enhanced differential extraction device
FR2760838B1 (fr) * 1997-03-13 1999-05-21 Corning Inc Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit
FR2762910B1 (fr) 1997-05-05 1999-06-11 Bio Merieux Dispositif de transfert d'un liquide
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US6002475A (en) * 1998-01-28 1999-12-14 Careside, Inc. Spectrophotometric analytical cartridge
US5916522A (en) * 1997-08-07 1999-06-29 Careside, Inc. Electrochemical analytical cartridge
JP2001518624A (ja) 1997-09-26 2001-10-16 ユニバーシティ・オブ・ワシントン 同時の粒子分離および化学反応
US6723290B1 (en) 1998-03-07 2004-04-20 Levine Robert A Container for holding biologic fluid for analysis
EP1075328B1 (de) * 1998-05-01 2005-11-16 Gen-Probe Incorporated Automatisiertes diagnostisches analyseverfahren
WO1999060397A1 (en) 1998-05-18 1999-11-25 University Of Washington Liquid analysis cartridge
US6830729B1 (en) 1998-05-18 2004-12-14 University Of Washington Sample analysis instrument
US6780617B2 (en) 2000-12-29 2004-08-24 Chen & Chen, Llc Sample processing device and method
DE19903704C1 (de) * 1999-01-30 2000-11-30 Fresenius Medical Care De Gmbh Aufnahmeeinheit für Lösungen, insbesondere Lösungen zur Kalibrierung von Sensoren zur Messung physiologisch relevanter Parameter
EP1181098B2 (de) * 1999-05-28 2011-07-06 Cepheid Patrone zum durchführen einer chemischen reaktion
WO2001026813A2 (en) * 1999-10-08 2001-04-19 Micronics, Inc. Microfluidics without electrically of mechanically operated pumps
FR2806009B1 (fr) * 2000-03-07 2002-05-31 Bio Merieux Procede de mise en oeuvre d'une carte d'analyse
KR100401389B1 (ko) * 2000-10-27 2003-10-17 김희태 핵산 검출 방법, 이를 위한 키트 및 이 키트를 구동시키기위한 구동장치
AU2002259017B2 (en) * 2001-04-26 2007-08-16 Boston Biomedica, Inc. Multichamber device and uses thereof for processing of biological samples
WO2003022435A2 (en) 2001-09-11 2003-03-20 Iquum, Inc. Sample vessels
DE10258840A1 (de) 2002-01-28 2003-08-07 Eppendorf Ag Stapelanordnung von Reaktionsgefäßen
GB0227765D0 (en) * 2002-11-28 2003-01-08 Secr Defence Apparatus for processing a fluid sample
WO2004061418A2 (en) 2002-12-26 2004-07-22 Meso Scale Technologies, Llc. Assay cartridges and methods of using the same
JP4632262B2 (ja) 2003-02-05 2011-02-16 アイキューム，インク． サンプルの処理
US7854897B2 (en) 2003-05-12 2010-12-21 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
DE10330804A1 (de) 2003-07-08 2005-04-28 Fresenius Medical Care De Gmbh Einwegkassette
JP4208820B2 (ja) 2003-11-28 2009-01-14 株式会社東芝 核酸検出カセット
GB2416030B (en) * 2004-01-28 2008-07-23 Norchip As A diagnostic system for carrying out a nucleic acid sequence amplification and detection process
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
JP4127679B2 (ja) 2004-03-18 2008-07-30 株式会社東芝 核酸検出カセット及び核酸検出装置
US7550267B2 (en) 2004-09-23 2009-06-23 University Of Washington Microscale diffusion immunoassay utilizing multivalent reactants
DE102004051573B4 (de) * 2004-10-22 2007-03-15 Yokogawa Electric Corporation, Musashino Verfahren zur Behandlung einer Abfallflüssigkeit in Chemischen Reaktions-Patronen und chemische Reaktions-Patrone, in der das Verfahren angewendet wird
CA2587085C (en) * 2004-10-27 2017-08-08 Cepheid Closed-system multi-stage nucleic acid amplification reactions
CN100462710C (zh) * 2004-11-09 2009-02-18 横河电机株式会社 在盒中处理废液的方法及应用此方法的化学反应盒
US8008066B2 (en) 2005-03-10 2011-08-30 Gen-Probe Incorporated System for performing multi-formatted assays
WO2006121997A2 (en) 2005-05-09 2006-11-16 Idaho Technology, Inc. Self-contained biological analysis
AU2006261953B2 (en) * 2005-06-24 2012-02-23 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
JP4692200B2 (ja) * 2005-10-06 2011-06-01 横河電機株式会社 化学処理用カートリッジおよびその使用方法
DE102006010958A1 (de) * 2006-03-06 2007-09-13 Directif Gmbh Verfahren zur Durchführung einer Reaktion zur Vervielfältigung einer Nukleinsäure
EP2049261B1 (de) 2006-07-28 2018-07-04 Diagnostics for the Real World, Ltd Vorrichtung, system und verfahren zur verarbeitung einer probe
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
CN101541962A (zh) 2007-03-23 2009-09-23 株式会社东芝 核酸检测盒以及核酸检测装置
US8633013B2 (en) * 2007-05-03 2014-01-21 Clondiag Gmbh Assays
GB2456079B (en) * 2007-08-17 2010-07-14 Diagnostics For The Real World Device, system and method for processing a sample
EP2042237A1 (de) * 2007-09-28 2009-04-01 Koninklijke Philips Electronics N.V. Reaktorsystem mit Reaktionskammern und Verfahren zum Füllen und Entleeren der Reaktionskammern
US7850917B2 (en) * 2008-03-11 2010-12-14 Ortho-Clinical Diagnostics, Inc. Particle agglutination in a tip
CA2638458A1 (en) 2008-07-31 2010-01-31 Spartan Bioscience Inc. Thermal recycling by positioning relative to fixed-temperature source
EP2410063B1 (de) 2009-03-19 2018-03-07 Kaneka Corporation Verfahren, kit und vorrichtung zur nukleinsäureerkennung
CA2784353C (en) 2009-12-18 2015-11-03 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge
US9199233B2 (en) 2010-03-31 2015-12-01 Abbott Point Of Care, Inc. Biologic fluid analysis cartridge with deflecting top panel
US9046507B2 (en) 2010-07-29 2015-06-02 Gen-Probe Incorporated Method, system and apparatus for incorporating capacitive proximity sensing in an automated fluid transfer procedure
EP2620508B1 (de) * 2010-09-22 2017-09-06 Kaneka Corporation Verfahren und vorrichtung zum nachweis von nukleinsäure und kit dafür
EP2624955A1 (de) * 2010-10-07 2013-08-14 BOEHRINGER INGELHEIM microParts GmbH Mikrofluidische plattform
ES2533839T3 (es) 2010-12-30 2015-04-15 Abbott Point Of Care, Inc. Cartucho de análisis de fluido biológico con porción de manipulación de muestra y porción de cámara de análisis
WO2012116308A1 (en) 2011-02-24 2012-08-30 Gen-Probe Incorporated Systems and methods for distinguishing optical signals of different modulation frequencies in an optical signal detector
WO2013028980A1 (en) 2011-08-24 2013-02-28 Abbott Point Of Care, Inc. Biologic fluid sample analysis cartridge
US11155871B2 (en) 2012-11-07 2021-10-26 Yale University Assessing risk of reading and language impairment
WO2017098321A1 (en) 2015-12-11 2017-06-15 Spartan Bioscience Inc. Tube sealing system and methods for nucleic acid amplification
JP2018174826A (ja) * 2017-04-14 2018-11-15 キヤノンメディカルシステムズ株式会社 核酸調製器具
JP6863074B2 (ja) * 2017-05-24 2021-04-21 住友ゴム工業株式会社 マイクロ流路チップ
CN114025880B (zh) * 2019-04-26 2023-10-10 斯蒂拉科技公司 聚合酶链反应设备及其用于压力控制释放流体的方法
CN114056769A (zh) * 2021-11-09 2022-02-18 杭州遂真生物技术有限公司 一种基于移动柱塞的气动一体式pcr检测试剂盒及其检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4585623A (en) * 1984-02-27 1986-04-29 Allelix Inc. Device for performing quantitative chemical and immunochemical assays
CA1339653C (en) * 1986-02-25 1998-02-03 Larry J. Johnson Appartus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
CA1284931C (en) * 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
US4690801A (en) * 1986-06-03 1987-09-01 Allelix Inc. Device for performing enzyme immunoassays
US4918025A (en) * 1987-03-03 1990-04-17 Pb Diagnostic Systems, Inc. Self contained immunoassay element
FR2612295B1 (fr) * 1987-03-11 1989-07-13 Abensour David Micro-analyseur automatique par colorimetrie ou bioluminescence
US4902624A (en) * 1987-11-23 1990-02-20 Eastman Kodak Company Temperature cycling cuvette

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EP0381501A3 (de) 1991-06-05
EP0381501B1 (de) 1994-06-08
FI94360B (fi) 1995-05-15
DK0381501T3 (da) 1994-07-04
EP0381501A2 (de) 1990-08-08
JP2536945B2 (ja) 1996-09-25
KR0161276B1 (ko) 1998-11-16
FI94360C (fi) 1995-08-25
DE69009510T2 (de) 1995-01-05
FI900535A0 (fi) 1990-02-02
JPH037571A (ja) 1991-01-14
CA1338505C (en) 1996-08-06
KR900013084A (ko) 1990-09-03
KR0161352B1 (ko) 1999-10-01

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