FR2760838B1 - Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit - Google Patents

Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit

Info

Publication number
FR2760838B1
FR2760838B1 FR9703014A FR9703014A FR2760838B1 FR 2760838 B1 FR2760838 B1 FR 2760838B1 FR 9703014 A FR9703014 A FR 9703014A FR 9703014 A FR9703014 A FR 9703014A FR 2760838 B1 FR2760838 B1 FR 2760838B1
Authority
FR
France
Prior art keywords
circuit
executing
sample
analysis
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9703014A
Other languages
English (en)
Other versions
FR2760838A1 (fr
Inventor
Thierry Luc Alain Dannoux
Isabelle Mathilde Jeann Geahel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corning Inc
Original Assignee
Corning Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corning Inc filed Critical Corning Inc
Priority to FR9703014A priority Critical patent/FR2760838B1/fr
Priority to PCT/US1998/004748 priority patent/WO1998040466A1/fr
Priority to EP98910303A priority patent/EP1007622A1/fr
Publication of FR2760838A1 publication Critical patent/FR2760838A1/fr
Application granted granted Critical
Publication of FR2760838B1 publication Critical patent/FR2760838B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/10Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0681Filter
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0809Geometry, shape and general structure rectangular shaped
    • B01L2300/0816Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0861Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087Multiple sequential chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1861Means for temperature control using radiation
    • B01L2300/1872Infrared light
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406Moving fluids with specific forces or mechanical means specific forces capillary forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0475Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
    • B01L2400/0481Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure squeezing of channels or chambers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Clinical Laboratory Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR9703014A 1997-03-13 1997-03-13 Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit Expired - Fee Related FR2760838B1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR9703014A FR2760838B1 (fr) 1997-03-13 1997-03-13 Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit
PCT/US1998/004748 WO1998040466A1 (fr) 1997-03-13 1998-03-11 Circuit a fluide integre permettant d'effectuer un traitement chimique ou biologique
EP98910303A EP1007622A1 (fr) 1997-03-13 1998-03-11 Circuit a fluide integre permettant d'effectuer un traitement chimique ou biologique

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9703014A FR2760838B1 (fr) 1997-03-13 1997-03-13 Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit

Publications (2)

Publication Number Publication Date
FR2760838A1 FR2760838A1 (fr) 1998-09-18
FR2760838B1 true FR2760838B1 (fr) 1999-05-21

Family

ID=9504719

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9703014A Expired - Fee Related FR2760838B1 (fr) 1997-03-13 1997-03-13 Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit

Country Status (3)

Country Link
EP (1) EP1007622A1 (fr)
FR (1) FR2760838B1 (fr)
WO (1) WO1998040466A1 (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884626B1 (en) 1998-04-27 2005-04-26 Corning Incorporated Redrawn capillary imaging reservoir
EP0955084B1 (fr) 1998-04-27 2006-07-26 Corning Incorporated Procédé pour le dépôt d'échantillons biologiques avec un réservoir capillaire refilé
US6350618B1 (en) 1998-04-27 2002-02-26 Corning Incorporated Redrawn capillary imaging reservoir
US6762061B1 (en) 1998-07-03 2004-07-13 Corning Incorporated Redrawn capillary imaging reservoir
KR100451154B1 (ko) * 2001-07-24 2004-10-02 엘지전자 주식회사 기판 내에서 유체를 조작하는 방법 및 이를 위한 장치
US7854897B2 (en) 2003-05-12 2010-12-21 Yokogawa Electric Corporation Chemical reaction cartridge, its fabrication method, and a chemical reaction cartridge drive system
DE10353985A1 (de) * 2003-11-19 2005-06-23 Olympus Biosystems Gmbh Einrichtung und Verfahren zum Manipulieren und Analysieren von Mikroobjekten auf Grundlage eines zumindest bereichsweise als fluidisches Mikrosystem oder/und Chipsystem ausgeführten Mikrosystems
US8961900B2 (en) 2004-04-28 2015-02-24 Yokogawa Electric Corporation Chemical reaction cartridge, method of producing chemical reaction cartridge, and mechanism for driving chemical reaction cartridge
US8394608B2 (en) * 2005-05-09 2013-03-12 Biofire Diagnostics, Inc. Self-contained biological analysis
JP4692200B2 (ja) * 2005-10-06 2011-06-01 横河電機株式会社 化学処理用カートリッジおよびその使用方法
US9839909B2 (en) 2006-07-28 2017-12-12 Diagnostics For The Real World, Ltd. Device, system and method for processing a sample
US9102911B2 (en) 2009-05-15 2015-08-11 Biofire Diagnostics, Llc High density self-contained biological analysis
GB2456079B (en) 2007-08-17 2010-07-14 Diagnostics For The Real World Device, system and method for processing a sample
DE102009001261A1 (de) * 2008-10-06 2010-04-15 Aj Ebiochip Gmbh Vorrichtung und Verfahren zur Ausführung mehrerer paralleler PCR-Reaktionen im Durchflussverfahren
DE102009050175A1 (de) * 2009-10-21 2011-04-28 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Biochip, zugehöriges Untersuchungsgerät und entsprechendes Betriebsverfahren
DE102013221525A1 (de) * 2013-10-23 2015-04-23 Robert Bosch Gmbh Analyseeinheit zur Durchführung einer Polymerase-Kettenreaktion, Analysevorrichtung, Verfahren zum Betrieb einer solchen Analyseeinheit und Verfahren zum Herstellen einer solchen Analyseeinheit
US10046322B1 (en) * 2018-03-22 2018-08-14 Talis Biomedical Corporation Reaction well for assay device
US20220250079A1 (en) * 2021-02-05 2022-08-11 EGI Tech (Qing Dao) Co., Limited Integrated reagent cartridge

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3666631A (en) * 1969-12-31 1972-05-30 Nasa Bacterial contamination monitor
US4690801A (en) * 1986-06-03 1987-09-01 Allelix Inc. Device for performing enzyme immunoassays
US4859421A (en) * 1987-06-23 1989-08-22 The Research Foundation Of State University Of New York Disposable antigen concentrator and detector
CA1338505C (fr) * 1989-02-03 1996-08-06 John Bruce Findlay Cuvette de retenue pour pcr et methode d'utilisation
KR100220989B1 (ko) * 1989-02-03 1999-09-15 피터 지. 스트링거 구아니딘 유도체 및 이를 함유하는 약제학적 조성물
US5154888A (en) * 1990-10-25 1992-10-13 Eastman Kodak Company Automatic sealing closure means for closing off a passage in a flexible cuvette
FR2672231A1 (fr) * 1991-02-01 1992-08-07 Eibet Appareil d'execution automatique repetee d'un cycle thermique, notamment pour l'amplification du nombre d'une sequence definie d'acide nucleique.
EP0542422A1 (fr) * 1991-11-12 1993-05-19 General Atomics Plaque de microtitrage à puits multiples
US5254479A (en) * 1991-12-19 1993-10-19 Eastman Kodak Company Methods for preventing air injection into a detection chamber supplied with injected liquid
DE69305046T2 (de) * 1992-10-23 1997-04-03 Johnson & Johnson Clin Diag Regelung des Durchflusses in einem eingeschlossenen Behälter
US5422271A (en) * 1992-11-20 1995-06-06 Eastman Kodak Company Nucleic acid material amplification and detection without washing
DK0662345T3 (da) * 1994-01-06 2000-08-07 Johnson & Johnson Clin Diag Apparat til at opvarme et fluidbærende rum i en reaktionskuvette

Also Published As

Publication number Publication date
WO1998040466A1 (fr) 1998-09-17
EP1007622A1 (fr) 2000-06-14
FR2760838A1 (fr) 1998-09-18

Similar Documents

Publication Publication Date Title
FR2760838B1 (fr) Circuit fluidique integre d'execution d'un processus de preparation ou d'analyse d'un echantillon de matiere fluide, son procede de fabrication et appareil d'exploitation de ce circuit
FR2783179B1 (fr) Dispositif d'analyse chimique ou biologique comprenant une pluralite de sites d'analyse sur un support, et son procede de fabrication
FR2781886B1 (fr) Micro-systeme a multiple points d'analyse chimique ou biologique
NO20004452L (no) FremgangsmÕte og apparatur for Õ utføre kjemiske, kvantitative og semi-kvantitative analyser av en urinprøve
DE69530861D1 (de) Vorrichtung zur durchführung eines oder mehrerer kompetitiver immunoassays
NO20004454D0 (no) Apparat for analysering av hovedsakelig ufortynnete prøver av biologiske fluider
DE69523693D1 (de) Analysevorrichtung und Verfahren zur Analyse von biologischer Flüssigkeit
PL357539A1 (en) A test-slip for determining concentration of at least one analyte in a physiological specimen, method of determining concentration of at least one analyte in a physiological specimen, method of obtaining a number of reactive zones on such test-slip and a test-kit for determining concentration of at least one analyte in a physiological specimen
DE58909018D1 (de) Testträger für die Analyse einer Probenflüssigkeit, Verfahren zur Durchführung einer solchen Analyse und Herstellungsverfahren.
BR9508959A (pt) "Detecção e tratamento de cancer"
DE3689856D1 (de) Analyseverfahren und vorrichtung für biologische specimen.
EP1141699A4 (fr) Dispositifs et procedes servant a effectuer des methodes de determination de coagulation sanguine par detection piezo-electrique
DE59105165D1 (de) Vorrichtung zur Aufbereitung oder Vorbereitung von flüssigen Proben für eine chemische Analyse.
DE69413012D1 (de) Integrierte vorrichtung für chemische verfahrensschritte und herstellungsverfahren dafür
FI980874A0 (fi) Menetelmä ja laite pienten nestemäärien kemiallisen analyysin suorittamiseksi
GR3030430T3 (en) Method and apparatus for fabricating microarrays of biological samples
EP0407800A3 (en) Analysis method for determining substances from biological fluids
DE3680473D1 (de) Vorrichtung und verfahren zur infrarot-optisch-elektronischen qualitativen analyse eines fluids, unabhaengig von seiner temperatur.
DE69006126D1 (de) Nukleinsäureprüfungswerkstoff und seine anwendung für die detektion einer vorausbestimmten nukleinsäure.
FR2777293B1 (fr) Procede d'electro-separation d'un echantillon biologique et dispositif de mise en oeuvre
IL143098A0 (en) A method of detecting the presence of an analyte in a biological sample
FR2810405B3 (fr) Dispositif pour analyser une substance et procede d'analyse
NO20012150L (no) Kvantitativt kjemisk analysemetode, anordning/innretning, samt anvendelse av nevnte metode og analysesett
DE69618467D1 (de) Vorrichtung zum übertragen von mikro-mengen von flüssigen proben
DE3689944D1 (de) "On line"-Prüf- und -Analysevorrichtung und -Verfahren welche eine Stoffbilanz von einer chemischen Reaktion erlauben.

Legal Events

Date Code Title Description
ST Notification of lapse