DE69001991D1 - Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten. - Google Patents

Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.

Info

Publication number
DE69001991D1
DE69001991D1 DE9090120880T DE69001991T DE69001991D1 DE 69001991 D1 DE69001991 D1 DE 69001991D1 DE 9090120880 T DE9090120880 T DE 9090120880T DE 69001991 T DE69001991 T DE 69001991T DE 69001991 D1 DE69001991 D1 DE 69001991D1
Authority
DE
Germany
Prior art keywords
polypeptide
active substance
applications containing
liquid medicinal
medicinal applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE9090120880T
Other languages
English (en)
Other versions
DE69001991T2 (de
Inventor
Giancarlo Ceschel
Antonella Maria Segu
Celestino Ronchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PH&T S.R.L., MAILAND/MILANO, IT
Original Assignee
Phidea SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT8922398A external-priority patent/IT8922398A0/it
Priority claimed from IT02094690A external-priority patent/IT1243343B/it
Application filed by Phidea SpA filed Critical Phidea SpA
Publication of DE69001991D1 publication Critical patent/DE69001991D1/de
Application granted granted Critical
Publication of DE69001991T2 publication Critical patent/DE69001991T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0031—Rectum, anus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Otolaryngology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE9090120880T 1989-11-16 1990-10-31 Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten. Expired - Fee Related DE69001991T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8922398A IT8922398A0 (it) 1989-11-16 1989-11-16 Composizioni farmaceutiche ad elevato assorbimento e stabilita', comprendente una calcitonina come sostanza attiva.
IT02094690A IT1243343B (it) 1990-07-16 1990-07-16 Composizione farmaceutica liquida per la somministrazione nasale contenente un polipeptide come sostanza attiva

Publications (2)

Publication Number Publication Date
DE69001991D1 true DE69001991D1 (de) 1993-07-22
DE69001991T2 DE69001991T2 (de) 1993-09-23

Family

ID=26327710

Family Applications (1)

Application Number Title Priority Date Filing Date
DE9090120880T Expired - Fee Related DE69001991T2 (de) 1989-11-16 1990-10-31 Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.

Country Status (4)

Country Link
US (1) US5124315A (de)
EP (1) EP0432431B1 (de)
DE (1) DE69001991T2 (de)
ES (1) ES2067624T3 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222249B1 (hu) 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
DE4222647A1 (de) * 1991-07-15 1993-01-21 Sandoz Ag Peptid-zubereitungen
IT1265647B1 (it) * 1992-11-18 1996-11-22 Farmin Srl Composizione farmaceutiche topiche per le allergie respiratorie
US5482931A (en) * 1993-06-29 1996-01-09 Ferring Ab Stabilized pharmaceutical peptide compositions
CZ282456B6 (cs) * 1993-06-29 1997-07-16 Ferring B. V. Kompozice pro nasální podání desmopressinu
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
US8765177B2 (en) * 1997-09-12 2014-07-01 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
US7153845B2 (en) * 1998-08-25 2006-12-26 Columbia Laboratories, Inc. Bioadhesive progressive hydration tablets
GB9806937D0 (en) 1998-03-31 1998-05-27 Procter & Gamble A spray device
US6187332B1 (en) * 1999-06-14 2001-02-13 Wisconsin Alumni Research Foundation Acidic buffered nasal spray
AU783952B2 (en) 2000-02-04 2006-01-05 Unigene Laboratories, Inc. Nasal calcitonin formulations
AT409081B (de) * 2000-02-16 2002-05-27 Gebro Pharma Gmbh Stabile, nasal, oral oder sublingual anwendbare pharmazeutische zubereitung
WO2003097080A1 (en) * 2002-05-15 2003-11-27 Sun Pharmaceutical Industries Limited A stable aqueous composition of a peptide
US7812120B2 (en) * 2003-03-21 2010-10-12 Par Pharmaceutical, Inc. Nasal calcitonin formulations containing chlorobutanol
US9744239B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9687526B2 (en) 2015-01-30 2017-06-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9937223B2 (en) 2015-01-30 2018-04-10 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9925233B2 (en) 2015-01-30 2018-03-27 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9750785B2 (en) 2015-01-30 2017-09-05 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension
US9744209B2 (en) 2015-01-30 2017-08-29 Par Pharmaceutical, Inc. Vasopressin formulations for use in treatment of hypotension

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4900730A (en) * 1981-01-14 1990-02-13 Toyo Jozo Co., Ltd. Preparation which promotes the absorption of peptides
JPS57130961A (en) * 1981-02-04 1982-08-13 Seiwa Kasei:Kk Polypeptide derived from quaternary trimethylammonium
JPS57188526A (en) * 1981-05-14 1982-11-19 Takeda Chem Ind Ltd Peptide-containing pharmaceutical preparation
US4476116A (en) * 1982-12-10 1984-10-09 Syntex (U.S.A.) Inc. Polypeptides/chelating agent nasal compositions having enhanced peptide absorption
US4466960A (en) * 1983-10-18 1984-08-21 Thompson Medical Co., Inc. Analgesic-diuretic compositions
US4658830A (en) * 1984-08-08 1987-04-21 Survival Technology, Inc. Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms
JPS61194034A (ja) * 1985-02-25 1986-08-28 Teijin Ltd 経鼻投与用粉末状組成物
DE3768232D1 (de) * 1986-12-19 1991-04-04 Duphar Int Res Dimethyldioctadecylammoniumbromid enthaltende stabilisierte adjuvanssuspension.
IT1222395B (it) * 1987-07-30 1990-09-05 Pierrel Spa Composizione farmaceutica per somministrazione intranasale comprendente l'ormone ghrh,un agonista colinergico e/o un sale biliare
IT1223132B (it) * 1987-11-13 1990-09-12 Isf Spa Composizione farmaceutica per somministrazione nasale
IL91856A0 (en) * 1988-10-11 1990-06-10 Schiapparelli Salute Spa Pharmaceutical compositions comprising calcitonin for intranasal administration and a spray unit for the administration of the same
US5015626A (en) * 1989-08-02 1991-05-14 Iowa State University Research Foundation, Inc. Porcine somatotropin to improve meat quality of pigs
US5015627A (en) * 1990-07-20 1991-05-14 Smithkline Beecham Corporation Stabilized somatotropin for parenteral administration

Also Published As

Publication number Publication date
ES2067624T3 (es) 1995-04-01
DE69001991T2 (de) 1993-09-23
EP0432431A1 (de) 1991-06-19
US5124315A (en) 1992-06-23
EP0432431B1 (de) 1993-06-16

Similar Documents

Publication Publication Date Title
DE69001991D1 (de) Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.
ATE121089T1 (de) Optisch aktives 5h-pyrrolo(3,4-b>pyrazinderivat, seine herstellung und pharmazeutische zubereitungen die es enthalten.
DE3579655D1 (de) Arzneimittel zur externen anwendung enthaltend aktives vitamin-d3.
DE3578620D1 (de) Arzneimittel zur aeusserlichen anwendung.
DE69018647D1 (de) Arzneimittel.
DE3869114D1 (de) Fluessigkristallverbindung und gemische, die diese verbindung enthalten.
DE3771402D1 (de) Thermoplaste, die benzocyclobutengruppen enthalten.
NL192721B (nl) Benzonorborneenderivaten, werkwijzen voor het bereiden ervan alsmede geneeskundige en cosmetische preparaten, die dergelijke derivaten bevatten.
DE69008945D1 (de) Gerät für die Anwendung von Supraleitfähigkeit.
DE69205466D1 (de) Mittel zur Kontrolle von Hautfalten, die die Arg-Ser-Arg-Lys-Sequenzen enthalten.
NL192192B (nl) Farmaceutische preparaten, die menselijk insuline en menselijk C-peptide bevatten.
DE3863154D1 (de) Durch hochdruckfluessigkeit betriebene kolben-und-zylinder-vorrichtung.
DK0391185T3 (da) 1,8-Naphthyridiner
DE68914817D1 (de) Oxydisches supraleitendes Material, dessen Herstellungsprozess und Anwendung.
DE68906992D1 (de) Indanylring enthaltende pyrethinester, deren herstellung und deren anwendung als pestizide.
DE3874390D1 (de) Carboxystyrol-derivate und arzneimittel, die sie als wirkstoff enthalten.
ATE84548T1 (de) Expression in e.coli von hybridpolypeptiden, die die sequenz des wachstumshormons ausloesenden faktors enthalten.
DE3670635D1 (de) Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
ATE90572T1 (de) Fluessige arzneimittel zur nasalen anwendung, die ein polypeptid als wirksubstanz enthalten.
TR26907A (tr) Yeni poliiodine bilesikleri, hazirlik prosesi ve bunlari iceren kontrast maddesi.
NL194166B (nl) Naftoxazinen en bereiding en toepassing daarvan. Hexahydronaft[2,3-b]-1,4-oxazinen en farmaceutische preparaten die ze bevatten.
DE58905106D1 (de) Neue 1,2-dithiol-3-thion-s-oxid-verbindungen enthaltende arzneimittel.
IT8719974A0 (it) Dispositivo per l'adduzione dosata di lega leggera liquida nel cilindro di pressione.
NL193316B (nl) Onverzadigde cycloalifatische verbindingen, en cosmetische en farmaceutische preparaten, die deze onverzadigde cycloalifatische verbindingen bevatten.
FR2599280B1 (fr) Pulverisateur de liquide.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: PH&T S.R.L., MAILAND/MILANO, IT

8339 Ceased/non-payment of the annual fee