DE68928264D1 - Biostabile, segmentierte, aliphatische Polyurethane und Verfahren zu ihrer Herstellung - Google Patents

Biostabile, segmentierte, aliphatische Polyurethane und Verfahren zu ihrer Herstellung

Info

Publication number
DE68928264D1
DE68928264D1 DE68928264T DE68928264T DE68928264D1 DE 68928264 D1 DE68928264 D1 DE 68928264D1 DE 68928264 T DE68928264 T DE 68928264T DE 68928264 T DE68928264 T DE 68928264T DE 68928264 D1 DE68928264 D1 DE 68928264D1
Authority
DE
Germany
Prior art keywords
biostable
segmented
processes
production
aliphatic polyurethanes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68928264T
Other languages
English (en)
Other versions
DE68928264T2 (de
Inventor
Arthur J Coury
Christoper M Hobot
Kurt Carlson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic Inc
Original Assignee
Medtronic Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtronic Inc filed Critical Medtronic Inc
Application granted granted Critical
Publication of DE68928264D1 publication Critical patent/DE68928264D1/de
Publication of DE68928264T2 publication Critical patent/DE68928264T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203—Polyhydroxy compounds
    • C08G18/3206—Polyhydroxy compounds aliphatic
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/32—Polyhydroxy compounds; Polyamines; Hydroxyamines
    • C08G18/3203—Polyhydroxy compounds
    • C08G18/3212—Polyhydroxy compounds containing cycloaliphatic groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/28—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the compounds used containing active hydrogen
    • C08G18/30—Low-molecular-weight compounds
    • C08G18/38—Low-molecular-weight compounds having heteroatoms other than oxygen
    • C08G18/3819—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen
    • C08G18/3823—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing -N-C=O groups
    • C08G18/3831—Low-molecular-weight compounds having heteroatoms other than oxygen having nitrogen containing -N-C=O groups containing urethane groups
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G18/00—Polymeric products of isocyanates or isothiocyanates
    • C08G18/06—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen
    • C08G18/70—Polymeric products of isocyanates or isothiocyanates with compounds having active hydrogen characterised by the isocyanates or isothiocyanates used
    • C08G18/72—Polyisocyanates or polyisothiocyanates
    • C08G18/74—Polyisocyanates or polyisothiocyanates cyclic
    • C08G18/75—Polyisocyanates or polyisothiocyanates cyclic cycloaliphatic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Materials For Medical Uses (AREA)
DE68928264T 1988-09-30 1989-09-29 Biostabile, segmentierte, aliphatische Polyurethane und Verfahren zu ihrer Herstellung Expired - Fee Related DE68928264T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/251,418 US4873308A (en) 1988-09-30 1988-09-30 Biostable, segmented aliphatic polyurethanes and process therefor

Publications (2)

Publication Number Publication Date
DE68928264D1 true DE68928264D1 (de) 1997-09-25
DE68928264T2 DE68928264T2 (de) 1998-03-05

Family

ID=22951887

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68928264T Expired - Fee Related DE68928264T2 (de) 1988-09-30 1989-09-29 Biostabile, segmentierte, aliphatische Polyurethane und Verfahren zu ihrer Herstellung

Country Status (6)

Country Link
US (1) US4873308A (de)
EP (1) EP0361950B1 (de)
JP (1) JP3080960B2 (de)
AU (1) AU615402B2 (de)
CA (1) CA1313280C (de)
DE (1) DE68928264T2 (de)

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CA2038141A1 (en) * 1990-08-30 1992-03-01 Kaneyoshi Ashida Energy-absorbing flexible polyurethane foam
US5159051A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Biostable polyurethane
US5159050A (en) * 1991-05-09 1992-10-27 Becton, Dickinson And Company Polyurethane and medical article therefrom
US5375609A (en) * 1992-01-27 1994-12-27 Medtronic, Inc. Pacing lead insulator
BE1006440A3 (fr) * 1992-12-21 1994-08-30 Dereume Jean Pierre Georges Em Endoprothese luminale et son procede de preparation.
US5419921A (en) * 1993-03-22 1995-05-30 Medtronic, Inc. Pacing lead insulator
US20020055710A1 (en) 1998-04-30 2002-05-09 Ronald J. Tuch Medical device for delivering a therapeutic agent and method of preparation
US5632772A (en) * 1993-10-21 1997-05-27 Corvita Corporation Expandable supportive branched endoluminal grafts
US5639278A (en) * 1993-10-21 1997-06-17 Corvita Corporation Expandable supportive bifurcated endoluminal grafts
US5723004A (en) * 1993-10-21 1998-03-03 Corvita Corporation Expandable supportive endoluminal grafts
US5855598A (en) * 1993-10-21 1999-01-05 Corvita Corporation Expandable supportive branched endoluminal grafts
US6140452A (en) * 1994-05-06 2000-10-31 Advanced Bio Surfaces, Inc. Biomaterial for in situ tissue repair
US20050043808A1 (en) * 1994-05-06 2005-02-24 Advanced Bio Surfaces, Inc. Knee joint prosthesis
DE69530891T2 (de) * 1994-06-27 2004-05-13 Corvita Corp., Miami Bistabile luminale Transplantat-Endoprothesen
US5741331A (en) * 1996-07-29 1998-04-21 Corvita Corporation Biostable elastomeric polymers having quaternary carbons
AU7178698A (en) 1996-11-15 1998-06-03 Advanced Bio Surfaces, Inc. Biomaterial system for in situ tissue repair
US6111052A (en) 1997-04-30 2000-08-29 Medtronic, Inc. Polyurethane and polyurea biomaterials for use in medical devices
DE69838479T2 (de) * 1997-05-08 2008-06-19 Medtronic, Inc., Minneapolis Segmentierte polyurethan biomaterialien enthaltende medizinische geräte
US6915168B1 (en) 1997-05-08 2005-07-05 Michael D. Benz Medical devices containing segmented polyurethane biomaterials
US6106454A (en) * 1997-06-17 2000-08-22 Medtronic, Inc. Medical device for delivering localized radiation
US6203536B1 (en) 1997-06-17 2001-03-20 Medtronic, Inc. Medical device for delivering a therapeutic substance and method therefor
WO1999007308A1 (en) 1997-08-08 1999-02-18 Sunscope International, Inc. Microporous stent and implantation device
US7658727B1 (en) 1998-04-20 2010-02-09 Medtronic, Inc Implantable medical device with enhanced biocompatibility and biostability
US5962018A (en) * 1998-04-28 1999-10-05 Avon Products, Inc. Method of treating the skin with organic acids in anhydrous microsphere delivery systems
US6013099A (en) 1998-04-29 2000-01-11 Medtronic, Inc. Medical device for delivering a water-insoluble therapeutic salt or substance
US6540780B1 (en) * 1998-11-23 2003-04-01 Medtronic, Inc. Porous synthetic vascular grafts with oriented ingrowth channels
US6400992B1 (en) 1999-03-18 2002-06-04 Medtronic, Inc. Co-extruded, multi-lumen medical lead
US6702848B1 (en) * 1999-07-20 2004-03-09 Peter Paul Zilla Foam-type vascular prosthesis with well-defined anclio-permissive open porosity
US6554857B1 (en) 1999-07-20 2003-04-29 Medtronic, Inc Transmural concentric multilayer ingrowth matrix within well-defined porosity
EP1315470B1 (de) 2000-08-28 2009-07-15 Disc Dynamics, Inc. System zur wiederherstellung von gelenkoberflächen von säugetieren
US20020183824A1 (en) * 2001-05-09 2002-12-05 Medtronic, Inc. Co-extruded, multi-lumen medical lead
EP1446437B1 (de) * 2001-11-14 2015-04-15 Medtronic, Inc. Quaternäre kohlenstoffe enthaltende verbindungen, medizinische geräte und verfahren
GB2399309A (en) * 2001-12-19 2004-09-15 Advanced Bio Surfaces Inc Bone smoothing method and system
JP4324478B2 (ja) * 2002-01-22 2009-09-02 アドバンスト バイオ サーフェイシズ，インコーポレイティド 間置関節形成システム
ES2309350T3 (es) * 2002-07-11 2008-12-16 Advanced Bio Surfaces, Inc. Metodo y equipo para artroplastia interposicional.
US20040086569A1 (en) * 2002-08-13 2004-05-06 Medtronic, Inc. Active agent delivery systems, medical devices, and methods
CA2494186A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a poly(ethylene-co-(meth)acrylate), medical device, and method
AU2003258230A1 (en) * 2002-08-13 2004-02-25 Medtronic, Inc Medical device exhibiting improved adhesion between polymeric coating and substrate
CA2495181A1 (en) 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a hydrophilic polymer, medical device, and method
EP1539265B1 (de) * 2002-08-13 2007-09-26 Medtronic, Inc. System zur abgabe von wirkstoffen mit einem hydrophoben cellulose-derivat
US20040033251A1 (en) * 2002-08-13 2004-02-19 Medtronic, Inc. Active agent delivery system including a polyurethane, medical device, and method
WO2004026936A1 (en) 2002-09-17 2004-04-01 Medtronic, Inc. Compounds containing quaternary carbons and silicon-containing groups, medical devices, and methods.
US20040054113A1 (en) * 2002-09-17 2004-03-18 Medtronic, Inc. Polymers with soft segments containing silane-containing groups, medical devices, and methods
US6984700B2 (en) * 2002-09-17 2006-01-10 Medtronic, Inc. Compounds containing silicon-containing groups, medical devices, and methods
EP1684820A2 (de) * 2003-08-13 2006-08-02 Medtronic, Inc. Systeme zur abgabe von wirkstoffen mit einer mischbaren polymermischung, medizinprodukte und -verfahren
WO2005018697A2 (en) * 2003-08-13 2005-03-03 Medtronic, Inc. Active agent delivery systems, including a single layer of a miscible polymer blend, medical devices, and methods
US20060282169A1 (en) * 2004-12-17 2006-12-14 Felt Jeffrey C System and method for upper extremity joint arthroplasty
US20060178497A1 (en) * 2005-02-04 2006-08-10 Clemson University And Thordon Bearings, Inc. Implantable biomedical devices including biocompatible polyurethanes
US9050393B2 (en) * 2005-02-08 2015-06-09 Bruce N. Saffran Medical devices and methods for modulation of physiology using device-based surface chemistry
US7591853B2 (en) 2005-03-09 2009-09-22 Vertebral Technologies, Inc. Rail-based modular disc nucleus prosthesis
US9737414B2 (en) 2006-11-21 2017-08-22 Vertebral Technologies, Inc. Methods and apparatus for minimally invasive modular interbody fusion devices
KR101464983B1 (ko) 2008-05-01 2014-11-25 스파인셀 프러프라이어테리 리미티드 조직 보형물의 형성 및 삽입기구 및 그의 시스템 및 방법
US9510953B2 (en) 2012-03-16 2016-12-06 Vertebral Technologies, Inc. Modular segmented disc nucleus implant
CN107531872B (zh) 2014-12-19 2021-03-26 海峡接入控股（私人）有限公司 聚氨酯

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1023390A (en) * 1965-02-01 1966-03-23 Gen Mills Inc Polyisocyanates and derivatives
US3799965A (en) * 1972-08-21 1974-03-26 Gen Mills Chem Alicyclic diisocyanates
DE2547866A1 (de) * 1975-10-25 1977-05-05 Basf Ag Waermebestaendige polyurethanelastomere
US4191818A (en) * 1975-10-25 1980-03-04 Basf Wyandotte Corporation Process for preparing heat-resistant polyurethane elastomers having no secondary softening range
AU560959B2 (en) * 1981-10-30 1987-04-30 Thermo Electron Corporation Polyurethane for medical purpose
DE3329775A1 (de) * 1983-08-18 1985-02-28 Bayer Ag, 5090 Leverkusen Thermoplastische polyurethane hoher waermestandfestigkeit auf basis von naphthylendiisocyanat, verfahren zu ihrer herstellung und ihre verwendung

Also Published As

Publication number Publication date
EP0361950A2 (de) 1990-04-04
EP0361950A3 (de) 1991-01-16
US4873308A (en) 1989-10-10
JP3080960B2 (ja) 2000-08-28
DE68928264T2 (de) 1998-03-05
CA1313280C (en) 1993-01-26
JPH02142817A (ja) 1990-05-31
EP0361950B1 (de) 1997-08-20
AU615402B2 (en) 1991-09-26
AU4142289A (en) 1990-04-05

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee