DE68926972D1 - Thienotriazoldiazepinverbindungen und deren pharmazeutische Anwendungen - Google Patents

Thienotriazoldiazepinverbindungen und deren pharmazeutische Anwendungen

Info

Publication number
DE68926972D1
DE68926972D1 DE68926972T DE68926972T DE68926972D1 DE 68926972 D1 DE68926972 D1 DE 68926972D1 DE 68926972 T DE68926972 T DE 68926972T DE 68926972 T DE68926972 T DE 68926972T DE 68926972 D1 DE68926972 D1 DE 68926972D1
Authority
DE
Germany
Prior art keywords
thienotriazole
pharmaceutical applications
diazepine compounds
compounds
paf
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68926972T
Other languages
English (en)
Other versions
DE68926972T2 (de
Inventor
Minoru Moriwaki
Hiroshi Tanaka
Michio Terasawa
Tetsuya Tahara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Application granted granted Critical
Publication of DE68926972D1 publication Critical patent/DE68926972D1/de
Publication of DE68926972T2 publication Critical patent/DE68926972T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
DE68926972T 1988-01-30 1989-01-30 Thienotriazoldiazepinverbindungen und deren pharmazeutische Anwendungen Expired - Fee Related DE68926972T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2040088 1988-01-30
JP10322188 1988-04-26
JP30836588 1988-12-06
JP31168888 1988-12-08

Publications (2)

Publication Number Publication Date
DE68926972D1 true DE68926972D1 (de) 1996-09-26
DE68926972T2 DE68926972T2 (de) 1997-01-16

Family

ID=27457375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68926972T Expired - Fee Related DE68926972T2 (de) 1988-01-30 1989-01-30 Thienotriazoldiazepinverbindungen und deren pharmazeutische Anwendungen

Country Status (7)

Country Link
US (1) US4937240A (de)
EP (1) EP0328924B1 (de)
KR (1) KR910004448B1 (de)
AT (1) ATE141605T1 (de)
CA (1) CA1324863C (de)
DE (1) DE68926972T2 (de)
ES (1) ES2095208T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
DE4010528A1 (de) * 1990-04-02 1991-10-17 Boehringer Ingelheim Kg Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
DE4027470A1 (de) * 1990-08-30 1992-03-05 Boehringer Ingelheim Kg Neue hetrazepinoide amide
JP2959598B2 (ja) * 1990-10-12 1999-10-06 吉富製薬株式会社 光学活性なチエノトリアゾロジアゼピン化合物
DE4107521A1 (de) * 1991-03-08 1992-09-10 Boehringer Ingelheim Kg Neue acylaminosubstituierte hetrazepine
AU2006296384A1 (en) * 2005-09-29 2007-04-05 Inpharmatica Limited Thiophene derivatives as PPAR agonists I
AR084070A1 (es) 2010-12-02 2013-04-17 Constellation Pharmaceuticals Inc Inhibidores del bromodominio y usos de los mismos
WO2012075456A1 (en) 2010-12-02 2012-06-07 Constellation Pharmaceuticals Bromodomain inhibitors and uses thereof
US9422292B2 (en) 2011-05-04 2016-08-23 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2012174487A2 (en) 2011-06-17 2012-12-20 Constellation Pharmaceuticals, Inc. Bromodomain inhibitors and uses thereof
WO2013184878A1 (en) 2012-06-06 2013-12-12 Constellation Pharmaceuticals, Inc. Benzo [b] isoxazoloazepine bromodomain inhibitors and uses thereof
TWI602820B (zh) 2012-06-06 2017-10-21 星宿藥物公司 溴域抑制劑及其用途
CA2952830C (en) 2014-06-20 2022-11-01 Constellation Pharmaceuticals, Inc. Crystalline forms of 2-((4s)-6-(4-chlorophenyl)-1-methyl-4h-benzo[c]isoxazolo[4,5-e]azepin-4-yl)acetamide

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994941A (en) * 1975-10-20 1976-11-30 The Upjohn Company Preparation of 1-(2-phthalimidoethyl)-4H-s-tiazolo[4,3-a][1,4]benzodiazepines
DE3435973A1 (de) * 1984-10-01 1986-04-10 Boehringer Ingelheim KG, 6507 Ingelheim Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
DE3502392A1 (de) * 1985-01-25 1986-07-31 Boehringer Ingelheim KG, 6507 Ingelheim Neue thieno-triazolo-1,4-diazepino-2- carbonsaeureamide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
EP0230942B1 (de) * 1986-01-21 1992-04-29 Boehringer Ingelheim Kg Thieno-1,4-diazepine
DE3610848A1 (de) * 1986-04-01 1987-10-15 Boehringer Ingelheim Kg Neue 1,4-diazepine
PH30676A (en) * 1986-07-22 1997-09-16 Boehringer Ingelhein Kg Hetrazepine compounds which have useful pharmaceutical utility
WO1988009333A1 (en) * 1987-05-28 1988-12-01 Yoshitomi Pharmaceutical Industries, Ltd. Thieno(triazolo)diazepine compound and medicinal application of the same
WO1988009792A1 (en) * 1987-06-08 1988-12-15 Yoshitomi Pharmaceutical Industries, Ltd. Ester-substituted thienotriazolodiazepine compounds and their medicinal use
EP0368175A1 (de) * 1988-11-06 1990-05-16 Boehringer Ingelheim Kg 3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.

Also Published As

Publication number Publication date
CA1324863C (en) 1993-11-30
EP0328924A2 (de) 1989-08-23
KR890011892A (ko) 1989-08-23
DE68926972T2 (de) 1997-01-16
US4937240A (en) 1990-06-26
ATE141605T1 (de) 1996-09-15
ES2095208T3 (es) 1997-02-16
EP0328924A3 (de) 1991-03-20
EP0328924B1 (de) 1996-08-21
KR910004448B1 (ko) 1991-06-29

Similar Documents

Publication Publication Date Title
SE9604786D0 (sv) New compounds
BR0211228A (pt) Composto, composição farmacêutica e seus usos
DE3888441D1 (de) Benzoxazin-Verbindungen und ihre pharmazeutische Anwendung.
NO306464B1 (no) Benzimidazolforbindelser, farmasöytiske preparater som omfatter slike forbindelser, samt anvendelse av forbindelsene for fremstilling av medikamenter
DE3779500D1 (de) Levodopa-methyl-ester enthaltende pharmazeutische zusammensetzungen, ihre herstellung und therapeutische verwendungen.
FR2678938B1 (fr) Derives de pyrrolidine, leur preparation et les medicaments les contenant.
NO171365C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater
DE69627042T2 (de) Isocumarinderivate und deren verwendung in medikamenten
DE68926972D1 (de) Thienotriazoldiazepinverbindungen und deren pharmazeutische Anwendungen
DE3587777D1 (de) Heterozyklische Verbindungen, deren Herstellung und Medikamente diese enthaltend.
DE3679920D1 (de) Spiro-3-heteroazolidinverbindungen und ihre salze, ihre herstellung und diese enthaltende pharmazeutische mittel.
DE3881073D1 (de) Naphthalenverbindungen und antiallergische und antiinflammatorische pharmazeutische mittel.
DK0876388T3 (da) Tricykliske erythromycinderivater
ATE211729T1 (de) Therapeutisch wirksame verbindungen
DE69322251D1 (de) Medizinische zusammensetzung
ATE114154T1 (de) Thienotriazolodiazepine und ihre pharmazeutische verwendung.
ATE161531T1 (de) Acridine-1,8-dionderivate als therapeutisches mittel
KR920002151A (ko) 15-케토-프로스타글란딘 화합물에 의한 염증성 질환 치료
ES2111352T3 (es) Uso de diester fosfato para el tratamiento de enfermedades retinianas.
DE69016284D1 (de) Antibiotikum GE 22270, Faktoren A1,A2,A3 und H.
DE69210091D1 (de) Leukotrien-B4-Antagonisten
ATE121459T1 (de) Antibiotika ge 2270 faktoren b1, b2, c1, d1, d2, e und t.
ATE116644T1 (de) Thiadiazinone und sie enthaltende arzneimittel, insbesondere mit positiv-inotroper und vasodilatierender wirksamkeit.
DE3872425D1 (de) Substituierte tetrahydroisochinolin-verbindungen, ihre herstellung und diese enthaltende pharmazeutische mittel.
KR910018028A (ko) 15- 데히드록시-16-옥소프로스타글란딘 화합물에 의한 생화학적 치료

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: WELFIDE CORP., OSAKA, JP

8339 Ceased/non-payment of the annual fee