DE3587777D1 - Heterozyklische Verbindungen, deren Herstellung und Medikamente diese enthaltend. - Google Patents
Heterozyklische Verbindungen, deren Herstellung und Medikamente diese enthaltend.Info
- Publication number
- DE3587777D1 DE3587777D1 DE85308227T DE3587777T DE3587777D1 DE 3587777 D1 DE3587777 D1 DE 3587777D1 DE 85308227 T DE85308227 T DE 85308227T DE 3587777 T DE3587777 T DE 3587777T DE 3587777 D1 DE3587777 D1 DE 3587777D1
- Authority
- DE
- Germany
- Prior art keywords
- production
- heterocyclic compounds
- medicines containing
- compounds
- medicines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/58—Two sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23899184 | 1984-11-12 | ||
JP21932785 | 1985-10-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3587777D1 true DE3587777D1 (de) | 1994-04-21 |
DE3587777T2 DE3587777T2 (de) | 1994-06-23 |
Family
ID=26523058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3587777T Expired - Fee Related DE3587777T2 (de) | 1984-11-12 | 1985-11-12 | Heterozyklische Verbindungen, deren Herstellung und Medikamente diese enthaltend. |
Country Status (8)
Country | Link |
---|---|
US (2) | US4855310A (de) |
EP (1) | EP0181779B1 (de) |
KR (1) | KR900004804B1 (de) |
AT (1) | ATE102930T1 (de) |
CA (1) | CA1269982A (de) |
DE (1) | DE3587777T2 (de) |
ES (9) | ES8707947A1 (de) |
PH (1) | PH22520A (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61186368A (ja) * | 1985-02-14 | 1986-08-20 | Kyorin Pharmaceut Co Ltd | 新規な抗アレルギ−薬およびその製造方法 |
US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
US5180730A (en) * | 1985-07-22 | 1993-01-19 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic compounds |
US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
JPH0667836B2 (ja) * | 1989-03-01 | 1994-08-31 | 東洋紡績株式会社 | アミド系化合物からなる抗アレルギー剤 |
US5102897A (en) * | 1990-03-27 | 1992-04-07 | Warner-Lambert Company | 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues |
DE4035599A1 (de) * | 1990-11-06 | 1992-05-07 | Dresden Arzneimittel | Neue 5-(phenoxyalkanoylamino)-uracile, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
JP2002504892A (ja) * | 1997-04-11 | 2002-02-12 | イーライ・リリー・アンド・カンパニー | ペプチド様アミノチオエーテル酸の組み合わせライブラリー |
CA2359112A1 (en) * | 1999-01-22 | 2000-07-27 | Elan Pharmaceuticals, Inc. | Fused ring heteroaryl and heterocyclic compounds which inhibit leukocyte adhesion mediated by vla-4 |
CN1231212C (zh) | 1999-01-22 | 2005-12-14 | 依兰制药公司 | 抑制vla-4介导的白细胞粘着的多环化合物 |
ES2339738T3 (es) | 1999-01-22 | 2010-05-25 | Elan Pharmaceuticals, Inc. | Derivados de acilo los cuales tratan trastornos relacionados con vla-4. |
US6436904B1 (en) | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
CA2361162A1 (en) | 1999-03-01 | 2000-09-08 | Elan Pharmaceuticals, Inc. | Alpha-aminoacetic acid derivatives useful as alpha 4 beta 7-receptor antagonists |
US6552073B1 (en) * | 2002-03-01 | 2003-04-22 | Exonhit Therapeutics Sa | Compounds and methods of treating cell proliferative diseases |
TW200307671A (en) * | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
TWI281470B (en) * | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
CA2489355A1 (en) * | 2002-06-13 | 2003-12-24 | Qlt Inc. | Methods of using isothiazole derivatives to treat cancer or inflammation |
CA2851103A1 (en) | 2005-09-29 | 2007-04-12 | Elan Pharmaceuticals, Inc. | Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4 |
NZ567270A (en) * | 2005-09-29 | 2011-06-30 | Elan Pharm Inc | Pyrimidinyl amide compounds which inhibit leukocyte adhesion mediated by VLA-4 |
KR20080100271A (ko) * | 2006-02-27 | 2008-11-14 | 엘란 파마슈티칼스, 인크. | Vla-4에 의해 매개되는 백혈구 부착을 억제하는 피리미디닐 술폰아미드 화합물 |
EP2424841A1 (de) * | 2009-04-27 | 2012-03-07 | Elan Pharmaceuticals Inc. | Pyridinonantagonisten von alpha-4-integrinen |
DK2482815T3 (en) | 2009-10-02 | 2018-06-06 | Avexxin As | ANTI-INFLAMMATORY 2-OXOTHIAZOLES AND 2-OXOOXAZOLES |
CN110128370A (zh) | 2013-01-29 | 2019-08-16 | 埃维克辛公司 | 抗炎症和抗肿瘤的2-氧代噻唑类和2-氧代噻吩类化合物 |
GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1546937A (en) * | 1976-07-29 | 1979-05-31 | Beecham Group Ltd | 2,4-diaminopyrimidine derivatives |
JPS591268B2 (ja) * | 1978-10-18 | 1984-01-11 | 興和株式会社 | チアジアゾ−ル誘導体 |
US4411905A (en) * | 1979-09-04 | 1983-10-25 | Richardson-Merrell Inc. | Antisecretory 1,2,4-triazole-3-thiols |
AU554388B2 (en) * | 1981-06-15 | 1986-08-21 | American Home Products Corporation | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acid derivatives |
EP0084673B1 (de) * | 1982-01-22 | 1986-04-02 | BASF Aktiengesellschaft | Aminothiadiazole, Verfahren zu ihrer Herstellung und ihre Verwendung zur Bekämpfung unerwünschten Pflanzenwuchses |
US4517188A (en) * | 1983-05-09 | 1985-05-14 | Mead Johnson & Company | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols |
US4672066A (en) * | 1985-04-22 | 1987-06-09 | Hoffmann-La Roche Inc. | Derivatives of 4-acetyl-3-hydroxy-2-alkyl-phenoxycarboxylic acids |
US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
-
1985
- 1985-11-07 PH PH33025A patent/PH22520A/en unknown
- 1985-11-11 ES ES548772A patent/ES8707947A1/es not_active Expired
- 1985-11-11 KR KR1019850008402A patent/KR900004804B1/ko not_active IP Right Cessation
- 1985-11-12 DE DE3587777T patent/DE3587777T2/de not_active Expired - Fee Related
- 1985-11-12 EP EP85308227A patent/EP0181779B1/de not_active Expired - Lifetime
- 1985-11-12 AT AT85308227T patent/ATE102930T1/de not_active IP Right Cessation
- 1985-11-12 CA CA000495080A patent/CA1269982A/en not_active Expired - Fee Related
-
1986
- 1986-06-25 ES ES556752A patent/ES8801188A1/es not_active Expired
- 1986-06-25 ES ES556750A patent/ES8801234A1/es not_active Expired
- 1986-06-25 ES ES556753A patent/ES8801189A1/es not_active Expired
- 1986-06-25 ES ES556746A patent/ES8801231A1/es not_active Expired
- 1986-06-25 ES ES556751A patent/ES8801235A1/es not_active Expired
- 1986-06-25 ES ES556748A patent/ES8801232A1/es not_active Expired
- 1986-06-25 ES ES556747A patent/ES8801187A1/es not_active Expired
- 1986-06-25 ES ES556749A patent/ES8801233A1/es not_active Expired
-
1988
- 1988-03-25 US US07/173,734 patent/US4855310A/en not_active Expired - Fee Related
-
1989
- 1989-06-07 US US07/362,959 patent/US4908368A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES556749A0 (es) | 1987-12-16 |
PH22520A (en) | 1988-10-17 |
US4855310A (en) | 1989-08-08 |
ES556748A0 (es) | 1987-12-16 |
ES8801187A1 (es) | 1987-12-16 |
ES556747A0 (es) | 1987-12-16 |
ES8801232A1 (es) | 1987-12-16 |
ES8801233A1 (es) | 1987-12-16 |
KR860004041A (ko) | 1986-06-16 |
EP0181779A1 (de) | 1986-05-21 |
ES556746A0 (es) | 1987-12-16 |
ATE102930T1 (de) | 1994-04-15 |
CA1269982A (en) | 1990-06-05 |
ES8707947A1 (es) | 1987-09-01 |
ES548772A0 (es) | 1987-09-01 |
EP0181779B1 (de) | 1994-03-16 |
ES8801231A1 (es) | 1987-12-16 |
ES556750A0 (es) | 1987-12-16 |
ES556751A0 (es) | 1987-12-16 |
ES556752A0 (es) | 1987-12-16 |
ES8801235A1 (es) | 1987-12-16 |
ES8801234A1 (es) | 1987-12-16 |
DE3587777T2 (de) | 1994-06-23 |
ES8801189A1 (es) | 1987-12-16 |
ES8801188A1 (es) | 1987-12-16 |
ES556753A0 (es) | 1987-12-16 |
US4908368A (en) | 1990-03-13 |
KR900004804B1 (ko) | 1990-07-06 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE3587777D1 (de) | Heterozyklische Verbindungen, deren Herstellung und Medikamente diese enthaltend. | |
NO171365C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive benzimidazolderivater | |
ES2080900T3 (es) | Derivados piranicos utiles como inhibidores de 5-lipoxigenasa. | |
NO933200L (no) | Substituerte cykloheksanderivater, fremgangsmåte til fremstilling derav og anvendelsen av forbindelsene til behandling av sykdommer | |
DE69210091T2 (de) | Leukotrien-B4-Antagonisten | |
NZ217418A (en) | Tricyclic heterocyclic compounds and pharmaceutical compositions | |
ES2028838T3 (es) | Procedimiento para la obtencion de nuevos derivados de 4,5-hidro-oxazoles. | |
KR880007070A (ko) | 백내장 치료용 약학 조성물 | |
ATE18203T1 (de) | (-)-15-deoxyspergualin, seine herstellung und arzneimittel mit diesem wirkstoff. | |
ATE75399T1 (de) | Therapeutikum zur behandlung von magengeschwueren. | |
ATE19632T1 (de) | Guanin-derivate. | |
DE3872425D1 (de) | Substituierte tetrahydroisochinolin-verbindungen, ihre herstellung und diese enthaltende pharmazeutische mittel. | |
DE3880304D1 (de) | 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung. | |
ATE115131T1 (de) | Harnstoff- und thioharnstoffderivate, herstellung und therapeutische verwendung. | |
DE3861273D1 (de) | Taurinderivat, seine herstellung und es enthaltende pharmazeutische zusammensetzungen. | |
ATE212842T1 (de) | Quinoxalin-derivate zur behandlung von tinnitus | |
ATE12241T1 (de) | Leukotrienaehnliche verbindungen, deren herstellung und verwendung in pharmazeutischen zusammensetzungen. | |
DE69103025T2 (de) | 2-imino-6-polyfluoralkyl-3-heterocyclylalkyl-benzothiazolinderivate, ihre herstellung und sie enthaltende arzneimittel. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |