PH22520A - Heterocyclic compounds having 4-lover alkyl-3-hydroxy-2-lower alkyl phenoxy-lower alkylene-y-group, and process of producing them - Google Patents
Heterocyclic compounds having 4-lover alkyl-3-hydroxy-2-lower alkyl phenoxy-lower alkylene-y-group, and process of producing themInfo
- Publication number
- PH22520A PH22520A PH33025A PH33025A PH22520A PH 22520 A PH22520 A PH 22520A PH 33025 A PH33025 A PH 33025A PH 33025 A PH33025 A PH 33025A PH 22520 A PH22520 A PH 22520A
- Authority
- PH
- Philippines
- Prior art keywords
- alkyl
- hydroxy
- producing
- group
- heterocyclic compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/58—Two sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/16—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D277/70—Sulfur atoms
- C07D277/74—Sulfur atoms substituted by carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
- C07D285/01—Five-membered rings
- C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
- C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
- C07D285/12—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
- C07D285/125—1,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
- C07D285/135—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23899184 | 1984-11-12 | ||
JP21932785 | 1985-10-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
PH22520A true PH22520A (en) | 1988-10-17 |
Family
ID=26523058
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PH33025A PH22520A (en) | 1984-11-12 | 1985-11-07 | Heterocyclic compounds having 4-lover alkyl-3-hydroxy-2-lower alkyl phenoxy-lower alkylene-y-group, and process of producing them |
Country Status (8)
Country | Link |
---|---|
US (2) | US4855310A (de) |
EP (1) | EP0181779B1 (de) |
KR (1) | KR900004804B1 (de) |
AT (1) | ATE102930T1 (de) |
CA (1) | CA1269982A (de) |
DE (1) | DE3587777T2 (de) |
ES (9) | ES8707947A1 (de) |
PH (1) | PH22520A (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS61186368A (ja) * | 1985-02-14 | 1986-08-20 | Kyorin Pharmaceut Co Ltd | 新規な抗アレルギ−薬およびその製造方法 |
US5180730A (en) * | 1985-07-22 | 1993-01-19 | Yamanouchi Pharmaceutical Co., Ltd. | Heterocyclic compounds |
US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
US4942245A (en) * | 1987-04-20 | 1990-07-17 | Kyorin Pharmaceutical Co., Ltd. | Benzimidazole Derivatives |
JPH0667836B2 (ja) * | 1989-03-01 | 1994-08-31 | 東洋紡績株式会社 | アミド系化合物からなる抗アレルギー剤 |
US5102897A (en) * | 1990-03-27 | 1992-04-07 | Warner-Lambert Company | 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues |
DE4035599A1 (de) * | 1990-11-06 | 1992-05-07 | Dresden Arzneimittel | Neue 5-(phenoxyalkanoylamino)-uracile, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
JP2002504892A (ja) * | 1997-04-11 | 2002-02-12 | イーライ・リリー・アンド・カンパニー | ペプチド様アミノチオエーテル酸の組み合わせライブラリー |
AR035838A1 (es) | 1999-01-22 | 2004-07-21 | Elan Pharm Inc | Compuestos multiciclicos que inhiben la adhesion de leucocitos mediada por vla-4 y el uso de los mismos para la preparacion de un medicamento |
DK1144388T3 (da) * | 1999-01-22 | 2010-05-25 | Elan Pharm Inc | Acyl-derivater, som behandler VLA-4-relaterede lidelser |
CN1336921A (zh) | 1999-01-22 | 2002-02-20 | 依兰制药公司 | 抑制vla-4介导的白细胞粘附的稠合环杂芳基和杂环化合物 |
US6436904B1 (en) * | 1999-01-25 | 2002-08-20 | Elan Pharmaceuticals, Inc. | Compounds which inhibit leukocyte adhesion mediated by VLA-4 |
JP2002538135A (ja) | 1999-03-01 | 2002-11-12 | エラン ファーマシューティカルズ,インコーポレイテッド | α4β7レセプターアンタゴニストとして有用なα−アミノ酢酸誘導体 |
US6552073B1 (en) * | 2002-03-01 | 2003-04-22 | Exonhit Therapeutics Sa | Compounds and methods of treating cell proliferative diseases |
TW200307671A (en) * | 2002-05-24 | 2003-12-16 | Elan Pharm Inc | Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins |
TWI281470B (en) * | 2002-05-24 | 2007-05-21 | Elan Pharm Inc | Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins |
WO2003105843A1 (en) * | 2002-06-13 | 2003-12-24 | Kinetek Pharmaceuticals, Inc. | Methods of using isothiazole derivatives to treat cancer or inflammation |
ATE502031T1 (de) | 2005-09-29 | 2011-04-15 | Elan Pharm Inc | Carbamatverbindungen, die die durch vla-4 vermittelte leukozytenadhäsion inhibieren |
KR20080059268A (ko) * | 2005-09-29 | 2008-06-26 | 엘란 파마슈티칼스, 인크. | Vla-4에 의해 매개되는 백혈구 부착을 억제하는피리미디닐 아미드 화합물 |
CA2643838A1 (en) * | 2006-02-27 | 2007-09-07 | Elan Pharmaceuticals, Inc. | Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4 |
CA2760151A1 (en) * | 2009-04-27 | 2010-11-04 | Elan Pharmaceuticals, Inc. | Pyridinone antagonists of alpha-4 integrins |
EP3431084A1 (de) | 2009-10-02 | 2019-01-23 | Avexxin AS | Antiinflammatorische 2-oxothiazole |
EP2951164B1 (de) | 2013-01-29 | 2019-06-05 | Avexxin AS | Entzündungshemmende und antitumorwirkende 2-oxothiazolverbindungen |
GB201413695D0 (en) | 2014-08-01 | 2014-09-17 | Avexxin As | Compound |
GB201604318D0 (en) | 2016-03-14 | 2016-04-27 | Avexxin As | Combination therapy |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1546937A (en) * | 1976-07-29 | 1979-05-31 | Beecham Group Ltd | 2,4-diaminopyrimidine derivatives |
JPS591268B2 (ja) * | 1978-10-18 | 1984-01-11 | 興和株式会社 | チアジアゾ−ル誘導体 |
US4411905A (en) * | 1979-09-04 | 1983-10-25 | Richardson-Merrell Inc. | Antisecretory 1,2,4-triazole-3-thiols |
AU554388B2 (en) * | 1981-06-15 | 1986-08-21 | American Home Products Corporation | Alpha-phenyl-2-(aza)benzothiazolylthioglycolic acid derivatives |
DE3270324D1 (en) * | 1982-01-22 | 1986-05-07 | Basf Ag | Aminothiadiazoles, process for their preparation and their use in combating unwanted plant growth |
US4517188A (en) * | 1983-05-09 | 1985-05-14 | Mead Johnson & Company | 1-Pyrimidinyloxy-3-hetaryl-alkylamino-2-propanols |
US4672066A (en) * | 1985-04-22 | 1987-06-09 | Hoffmann-La Roche Inc. | Derivatives of 4-acetyl-3-hydroxy-2-alkyl-phenoxycarboxylic acids |
US4803211A (en) * | 1985-07-22 | 1989-02-07 | Yamanouchi Pharmaceutical Co., Ltd. | Thiadizazole compounds as antagonists of SRS-A |
-
1985
- 1985-11-07 PH PH33025A patent/PH22520A/en unknown
- 1985-11-11 ES ES548772A patent/ES8707947A1/es not_active Expired
- 1985-11-11 KR KR1019850008402A patent/KR900004804B1/ko not_active IP Right Cessation
- 1985-11-12 DE DE3587777T patent/DE3587777T2/de not_active Expired - Fee Related
- 1985-11-12 AT AT85308227T patent/ATE102930T1/de not_active IP Right Cessation
- 1985-11-12 EP EP85308227A patent/EP0181779B1/de not_active Expired - Lifetime
- 1985-11-12 CA CA000495080A patent/CA1269982A/en not_active Expired - Fee Related
-
1986
- 1986-06-25 ES ES556753A patent/ES8801189A1/es not_active Expired
- 1986-06-25 ES ES556751A patent/ES8801235A1/es not_active Expired
- 1986-06-25 ES ES556749A patent/ES8801233A1/es not_active Expired
- 1986-06-25 ES ES556752A patent/ES8801188A1/es not_active Expired
- 1986-06-25 ES ES556747A patent/ES8801187A1/es not_active Expired
- 1986-06-25 ES ES556748A patent/ES8801232A1/es not_active Expired
- 1986-06-25 ES ES556750A patent/ES8801234A1/es not_active Expired
- 1986-06-25 ES ES556746A patent/ES8801231A1/es not_active Expired
-
1988
- 1988-03-25 US US07/173,734 patent/US4855310A/en not_active Expired - Fee Related
-
1989
- 1989-06-07 US US07/362,959 patent/US4908368A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ES8801235A1 (es) | 1987-12-16 |
ES8801231A1 (es) | 1987-12-16 |
ES8801234A1 (es) | 1987-12-16 |
ES556748A0 (es) | 1987-12-16 |
ES556752A0 (es) | 1987-12-16 |
ES556750A0 (es) | 1987-12-16 |
ES556746A0 (es) | 1987-12-16 |
ES8801232A1 (es) | 1987-12-16 |
US4855310A (en) | 1989-08-08 |
ES8707947A1 (es) | 1987-09-01 |
ES8801187A1 (es) | 1987-12-16 |
ES548772A0 (es) | 1987-09-01 |
KR860004041A (ko) | 1986-06-16 |
ES8801233A1 (es) | 1987-12-16 |
ES556753A0 (es) | 1987-12-16 |
EP0181779B1 (de) | 1994-03-16 |
ES556747A0 (es) | 1987-12-16 |
ES556749A0 (es) | 1987-12-16 |
DE3587777D1 (de) | 1994-04-21 |
US4908368A (en) | 1990-03-13 |
ES8801188A1 (es) | 1987-12-16 |
EP0181779A1 (de) | 1986-05-21 |
CA1269982A (en) | 1990-06-05 |
DE3587777T2 (de) | 1994-06-23 |
ES8801189A1 (es) | 1987-12-16 |
ES556751A0 (es) | 1987-12-16 |
ATE102930T1 (de) | 1994-04-15 |
KR900004804B1 (ko) | 1990-07-06 |
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