DE68924928T2 - Antikörper gegen latente Proteine von menschlichen Papillomavirus, diagnostische Systeme und Methoden. - Google Patents

Antikörper gegen latente Proteine von menschlichen Papillomavirus, diagnostische Systeme und Methoden.

Info

Publication number
DE68924928T2
DE68924928T2 DE68924928T DE68924928T DE68924928T2 DE 68924928 T2 DE68924928 T2 DE 68924928T2 DE 68924928 T DE68924928 T DE 68924928T DE 68924928 T DE68924928 T DE 68924928T DE 68924928 T2 DE68924928 T2 DE 68924928T2
Authority
DE
Germany
Prior art keywords
antibodies
methods
human papillomavirus
diagnostic systems
latent proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68924928T
Other languages
English (en)
Other versions
DE68924928D1 (de
Inventor
Joakim Dillner
Richard A Lerner
Richard Smith
D Elliot Parks D Elliot Parks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scripps Research Institute
Original Assignee
Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Institute filed Critical Scripps Research Institute
Application granted granted Critical
Publication of DE68924928D1 publication Critical patent/DE68924928D1/de
Publication of DE68924928T2 publication Critical patent/DE68924928T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/20011—Papillomaviridae
    • C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE68924928T 1988-05-16 1989-05-15 Antikörper gegen latente Proteine von menschlichen Papillomavirus, diagnostische Systeme und Methoden. Expired - Lifetime DE68924928T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19440788A 1988-05-16 1988-05-16
US07/323,614 US5180806A (en) 1988-05-16 1989-03-13 Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods

Publications (2)

Publication Number Publication Date
DE68924928D1 DE68924928D1 (de) 1996-01-11
DE68924928T2 true DE68924928T2 (de) 1996-10-17

Family

ID=26889974

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924928T Expired - Lifetime DE68924928T2 (de) 1988-05-16 1989-05-15 Antikörper gegen latente Proteine von menschlichen Papillomavirus, diagnostische Systeme und Methoden.

Country Status (10)

Country Link
US (3) US5180806A (de)
EP (1) EP0344940B1 (de)
JP (1) JP2918904B2 (de)
AT (1) ATE130855T1 (de)
CA (1) CA1341287C (de)
DE (1) DE68924928T2 (de)
DK (1) DK173264B1 (de)
ES (1) ES2082775T4 (de)
GR (1) GR3018773T3 (de)
PT (1) PT90574B (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9001705D0 (sv) * 1990-05-11 1990-05-11 Medscand Ab Saett foer diagnostik av virusbaerande tumoerer genom immunoassay
US5932412A (en) * 1990-05-11 1999-08-03 Euro-Diagnostica Ab Synthetic peptides in human papillomaviruses 1, 5, 6, 8, 11, 16, 18, 31, 33 and 56, useful in immunoassay for diagnostic purposes
DK0510912T3 (da) * 1991-04-24 1998-02-09 Morinaga Milk Industry Co Ltd Antimikrobielt peptid og antimikrobielt middel
ES2193133T3 (es) * 1991-07-13 2003-11-01 Dade Behring Marburg Gmbh Uso de peptidos derivados de los genes e6 y e7 de hpv-16 para fines.
DE4123760C2 (de) * 1991-07-18 2000-01-20 Dade Behring Marburg Gmbh Seroreaktive Bereiche auf den HPV 16 Proteinen E1 und E2
US5437951A (en) * 1992-09-03 1995-08-01 The United States Of America As Represented By The Department Of Health And Human Services Self-assembling recombinant papillomavirus capsid proteins
GB9306731D0 (en) * 1993-03-31 1993-05-26 Cancer Res Campaign Tech Vaccines
DE19819476C1 (de) * 1998-04-30 2000-01-05 Deutsches Krebsforsch Polypeptid mit immunogenen Eigenschaften und veränderten biologischen Funktionen eines Proteins
GB2353581B (en) 1999-08-27 2003-06-11 Uponor Ltd Swage lining
US7026443B1 (en) 1999-12-10 2006-04-11 Epimmune Inc. Inducing cellular immune responses to human Papillomavirus using peptide and nucleic acid compositions
JP2001172200A (ja) * 1999-12-17 2001-06-26 Meneki Seibutsu Kenkyusho:Kk ヒトナプシンａに対する抗体およびこれを用いる医薬
CN1433428A (zh) 2000-04-05 2003-07-30 冲击诊断公司 辨别人乳头瘤病毒的免疫学方法
EP1288292A1 (de) * 2001-08-31 2003-03-05 Leids Universitair Medisch Centrum Lange Peptiden die 22-40 Aminosäuren enthalten und die eine immunspezifische Immunantwort induzieren
CA2431500C (en) 2000-12-08 2016-06-07 Sjoerd Hendrikus Van Der Burg Long peptides of 22-45 amino acid residues that induce and/or enhance antigen specific immune responses
CA2432398A1 (en) * 2000-12-21 2002-06-27 Biosignature Diagnostics, Inc. Absorbance multiplex technology
US6933123B2 (en) 2001-04-05 2005-08-23 Yao Xiong Hu Peptides from the E2, E6, and E7 proteins of human papilloma viruses 16 and 18 for detecting and/or diagnosing cervical and other human papillomavirus associated cancers
GB2379220A (en) * 2001-08-13 2003-03-05 Univ York Antibodies to HPV E2 protein
MXPA06002311A (es) * 2003-09-05 2006-05-19 Genencor Int Epitopos de celulas t cd8+ del virus del papiloma humano (vph).
CA2551560A1 (en) * 2003-12-23 2005-07-14 Arbor Vita Corporation Antibodies for oncogenic strains of hpv and methods of their use
EP1732598A4 (de) * 2003-12-31 2009-08-26 Pharmexa Inc Auslösung von zellulären immunantworten gegen den humanen papillovirus unter verwendung von peptid und nucleinsäure-zusammensetzungen
US7972776B2 (en) * 2005-11-15 2011-07-05 Oncohealth Corporation Protein chips for HPV detection
US7732166B2 (en) * 2005-11-15 2010-06-08 Oncohealth Corporation Detection method for human pappilomavirus (HPV) and its application in cervical cancer
US8051950B2 (en) * 2006-08-03 2011-11-08 Glacier Bay, Inc. System for reducing acoustic energy
US8968995B2 (en) * 2008-11-12 2015-03-03 Oncohealth Corp. Detection, screening, and diagnosis of HPV-associated cancers
US20100003704A1 (en) * 2008-06-13 2010-01-07 Shuling Cheng IN SITU detection of early stages and late stages HPV infection
JP2010530362A (ja) * 2007-05-31 2010-09-09 アカデミシュ ジーケンハウス ライデン ハー．オー．デー．エン． ルムク 皮内ｈｐｖペプチドワクチン接種
JP2012526286A (ja) 2009-05-07 2012-10-25 オンコヘルス コーポレーション ヒトパピローマウイルス（ｈｐｖ）およびｈｐｖ関連癌の初期段階および後期段階の検出、スクリーニング、および診断のための高度または≧ｃｉｎ２の同定
EP3311833A3 (de) * 2009-08-26 2018-07-25 Selecta Biosciences, Inc. Zusammensetzungen zur induzierung von t-zellen-hilfe
WO2011084598A1 (en) 2010-01-08 2011-07-14 Oncohealth Corporation High throughput cell-based hpv immunoassays for diagnosis and screening of hpv-associated cancers
WO2011085231A2 (en) * 2010-01-08 2011-07-14 Selecta Biosciences, Inc. Synthetic virus-like particles conjugated to human papillomavirus capsid peptides for use as vaccines
CN103940993A (zh) * 2013-01-23 2014-07-23 艾托金生物医药（苏州）有限公司 用于检测抗人乳头瘤病毒抗体的抗原及试剂盒和应用
AU2018290856A1 (en) * 2017-06-28 2020-01-02 Regeneron Pharmaceuticals, Inc. Anti-human papillomavirus (HPV) antigen-binding proteins and methods of use thereof
CA3088837A1 (en) * 2018-01-24 2019-08-01 The Council Of The Queensland Institute Of Medical Research Hpv immunotherapy
WO2020028532A1 (en) 2018-08-02 2020-02-06 The Board Of Regents Of The University Of Texas System Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease
US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
MX2022011765A (es) 2020-03-26 2022-11-09 Provectus Pharmatech Inc Usos novedosos de xantenos halogenados en oncologia y virologia.
CN113512109B (zh) * 2021-03-09 2022-03-25 北京康乐卫士生物技术股份有限公司 一种抗人乳头瘤病毒31型的单克隆中和抗体及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6089755A (ja) * 1983-07-01 1985-05-20 フイリツプ・ジヨン・ベア−ド 診断用試薬及びその製造法並びにそれを用いる診断法
LU85462A1 (fr) * 1984-07-11 1986-02-12 Univ Louvain Nouvelles compositions polymeres,procedes pour leur production et leurs applications
US4777239A (en) * 1986-07-10 1988-10-11 The Board Of Trustees Of The Leland Stanford Junior University Diagnostic peptides of human papilloma virus

Also Published As

Publication number Publication date
US5401627A (en) 1995-03-28
DK234789D0 (da) 1989-05-12
ES2082775T3 (es) 1996-04-01
US5180806A (en) 1993-01-19
JPH0296593A (ja) 1990-04-09
EP0344940A2 (de) 1989-12-06
DK173264B1 (da) 2000-05-29
ES2082775T4 (es) 1996-08-01
EP0344940A3 (de) 1991-11-13
PT90574B (pt) 1994-09-30
US5486453A (en) 1996-01-23
ATE130855T1 (de) 1995-12-15
PT90574A (pt) 1989-11-30
JP2918904B2 (ja) 1999-07-12
DE68924928D1 (de) 1996-01-11
CA1341287C (en) 2001-08-28
GR3018773T3 (en) 1996-04-30
EP0344940B1 (de) 1995-11-29
DK234789A (da) 1989-11-17

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