DE68924464T2 - Interferon-gamma bindende Proteine. - Google Patents

Interferon-gamma bindende Proteine.

Info

Publication number
DE68924464T2
DE68924464T2 DE68924464T DE68924464T DE68924464T2 DE 68924464 T2 DE68924464 T2 DE 68924464T2 DE 68924464 T DE68924464 T DE 68924464T DE 68924464 T DE68924464 T DE 68924464T DE 68924464 T2 DE68924464 T2 DE 68924464T2
Authority
DE
Germany
Prior art keywords
protein
interferon
binding proteins
gamma binding
molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68924464T
Other languages
English (en)
Other versions
DE68924464D1 (de
Inventor
Daniela Novick
Yves Mory
Dina G Fischer
Michel Revel
Menachem Rubinstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yeda Research and Development Co Ltd
Original Assignee
Yeda Research and Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Research and Development Co Ltd filed Critical Yeda Research and Development Co Ltd
Application granted granted Critical
Publication of DE68924464D1 publication Critical patent/DE68924464D1/de
Publication of DE68924464T2 publication Critical patent/DE68924464T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7156—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE68924464T 1988-11-14 1989-11-14 Interferon-gamma bindende Proteine. Expired - Lifetime DE68924464T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL8837888A IL88378A (en) 1988-11-14 1988-11-14 Human interferon-gamma binding proteins their manufacture and pharmaceutical compositions comprising them

Publications (2)

Publication Number Publication Date
DE68924464D1 DE68924464D1 (de) 1995-11-09
DE68924464T2 true DE68924464T2 (de) 1996-03-28

Family

ID=11059418

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924464T Expired - Lifetime DE68924464T2 (de) 1988-11-14 1989-11-14 Interferon-gamma bindende Proteine.

Country Status (9)

Country Link
US (1) US5763210A (de)
EP (1) EP0369413B1 (de)
JP (1) JP3104187B2 (de)
AT (1) ATE128728T1 (de)
AU (1) AU620466B2 (de)
CA (1) CA2002833C (de)
DE (1) DE68924464T2 (de)
ES (1) ES2080060T3 (de)
IL (1) IL88378A (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL91562A0 (en) * 1989-09-07 1990-04-29 Yeda Res & Dev Interferon-gamma receptor fragment and its production
US5632988A (en) * 1989-10-23 1997-05-27 Schering Corporation Polypeptide inhibitors of gamma interferon
EP0528847B1 (de) * 1990-04-24 1994-09-28 Schering Corporation Lösliche verkürzte interferon-gamma rezeptoren
DE69322289T2 (de) 1992-12-29 1999-05-20 Genentech Inc Behandlung von entzündlichen darmerkrankungen mit interferon-gamma-inhibitoren
US20020025316A1 (en) 1995-08-18 2002-02-28 Ferguson Mark Williams James Pharmaceutical composition containing inhibitors of interferon-gamma
GB2304342A (en) * 1995-08-18 1997-03-19 Univ Manchester Pharmaceutical comprising either an inhibitor or a stimulator of interferon gamma
US7704944B2 (en) * 1997-08-14 2010-04-27 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
US7335743B2 (en) 2002-10-16 2008-02-26 Amgen Inc. Human anti-IFN-γ neutralizing antibodies as selective IFN-γ pathway inhibitors
US20190185559A1 (en) * 2016-09-02 2019-06-20 The Brigham And Women's Hospital, Inc. Compositions and methods for treating neoplasias

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78444A (en) * 1986-04-08 1992-05-25 Yeda Res & Dev Human gamma interferon-specific receptor protein,antibody against said protein,and compositions containing said protein and antibody
ATE132191T1 (de) * 1989-04-19 1996-01-15 Hoffmann La Roche Auflösbare interferon-gamma-rezeptoren sowie verfahren zu deren herstellung

Also Published As

Publication number Publication date
EP0369413B1 (de) 1995-10-04
US5763210A (en) 1998-06-09
CA2002833A1 (en) 1990-05-14
ATE128728T1 (de) 1995-10-15
EP0369413A3 (en) 1990-09-26
JPH02291269A (ja) 1990-12-03
AU620466B2 (en) 1992-02-20
CA2002833C (en) 2001-10-30
IL88378A0 (en) 1989-06-30
AU4469889A (en) 1990-05-31
IL88378A (en) 2000-11-21
ES2080060T3 (es) 1996-02-01
DE68924464D1 (de) 1995-11-09
JP3104187B2 (ja) 2000-10-30
EP0369413A2 (de) 1990-05-23

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition