DE69024279T2 - Cytokine - Google Patents

Cytokine

Info

Publication number
DE69024279T2
DE69024279T2 DE69024279T DE69024279T DE69024279T2 DE 69024279 T2 DE69024279 T2 DE 69024279T2 DE 69024279 T DE69024279 T DE 69024279T DE 69024279 T DE69024279 T DE 69024279T DE 69024279 T2 DE69024279 T2 DE 69024279T2
Authority
DE
Germany
Prior art keywords
derivatives
polypeptides
mediators
hybrid vectors
dnas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69024279T
Other languages
English (en)
Other versions
DE69024279D1 (de
Inventor
Karel Gerrit Odink
Lajos Tarcsay
Josef Brueggen
Walter Wiesendanger
Nico Cerletti
Clemens Sorg
Christiane Dewolf-Peeters
Jan Delabie
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of DE69024279D1 publication Critical patent/DE69024279D1/de
Publication of DE69024279T2 publication Critical patent/DE69024279T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3061—Blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Radar Systems Or Details Thereof (AREA)
  • Control Of Driving Devices And Active Controlling Of Vehicle (AREA)
  • Control Of Transmission Device (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69024279T 1989-07-05 1990-06-26 Cytokine Expired - Fee Related DE69024279T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898915414A GB8915414D0 (en) 1989-07-05 1989-07-05 Novel cytokines

Publications (2)

Publication Number Publication Date
DE69024279D1 DE69024279D1 (de) 1996-02-01
DE69024279T2 true DE69024279T2 (de) 1996-10-17

Family

ID=10659582

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69024279T Expired - Fee Related DE69024279T2 (de) 1989-07-05 1990-06-26 Cytokine

Country Status (14)

Country Link
US (2) US5411882A (de)
EP (1) EP0412050B1 (de)
JP (1) JPH0356499A (de)
AT (1) ATE131873T1 (de)
AU (1) AU649226B2 (de)
CA (1) CA2020303A1 (de)
DD (1) DD298948A5 (de)
DE (1) DE69024279T2 (de)
DK (1) DK0412050T3 (de)
ES (1) ES2081960T3 (de)
GB (1) GB8915414D0 (de)
GR (1) GR3018521T3 (de)
IE (1) IE70519B1 (de)
PT (1) PT94575B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0263072B1 (de) * 1986-10-03 1994-03-23 Ciba-Geigy Ag Lymphokin-ähnliche Peptide
EP0615451B1 (de) 1992-05-26 2005-12-07 Immunex Corporation Neue zytokine die cd30 binden
US6080407A (en) * 1993-05-17 2000-06-27 The Picower Institute For Medical Research Diagnostic assays for MIF
US6774227B1 (en) * 1993-05-17 2004-08-10 Cytokine Pharmasciences, Inc. Therapeutic uses of factors which inhibit or neutralize MIF activity
UY27304A1 (es) 2001-05-24 2002-12-31 Avanir Pharmaceuticals Inhibidores del factor inhibidor de la migración de los macrófagos y métodos para su identificación
TW200418829A (en) 2003-02-14 2004-10-01 Avanir Pharmaceutics Inhibitors of macrophage migration inhibitory factor and methods for identifying the same
WO2005021546A1 (en) * 2003-08-22 2005-03-10 Avanir Pharmaceuticals Substituted naphthyridine derivatives as inhibitors of macrophage migration inhibitory factor and their use in the treatment of human diseases
US7740856B2 (en) * 2005-12-20 2010-06-22 Isu Abxis Co., Ltd. Effect of BST2 on inflammation
US20080299128A1 (en) * 2006-06-20 2008-12-04 Myung Kim Effect of Bst2 on inflammation
KR100735800B1 (ko) 2004-12-20 2007-07-06 이수앱지스 주식회사 세포간 부착을 억제하는 분자
US8329186B2 (en) * 2004-12-20 2012-12-11 Isu Abxis Co., Ltd Treatment of inflammation using BST2 inhibitor
JP2008534502A (ja) * 2005-03-24 2008-08-28 アバニール・ファーマシューティカルズ マクロファージ遊走阻止因子の阻害剤としてのチエノピリジノン誘導体
MXPA05011139A (es) * 2005-10-17 2007-04-17 Concretos Translucidos S De R Formulacion para obtener una mezcla de concreto conductivo.
GB0605689D0 (en) * 2006-03-21 2006-05-03 Novartis Ag Organic compounds
US9249217B2 (en) * 2010-12-03 2016-02-02 Secretary, DHHS Bispecific EGFRvIII x CD3 antibody engaging molecules
WO2013050453A1 (en) 2011-10-07 2013-04-11 Baxter Healthcare S.A. Oxmif as a diagnostic marker

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0672158B2 (ja) * 1984-05-24 1994-09-14 チバ−ガイギ− アクチエンゲゼルシヤフト 精製されたヒトマクロファージ遊走阻止因子
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
EP0263072B1 (de) * 1986-10-03 1994-03-23 Ciba-Geigy Ag Lymphokin-ähnliche Peptide
EP0761685A3 (de) * 1987-10-02 1998-01-28 The Rockefeller University Von Makrophagen abstammender Entzündungsvermittler (mip-1 alpha und mip-1 beta)

Also Published As

Publication number Publication date
JPH0356499A (ja) 1991-03-12
PT94575B (pt) 1997-02-28
CA2020303A1 (en) 1991-01-06
ES2081960T3 (es) 1996-03-16
PT94575A (pt) 1991-03-20
US5411882A (en) 1995-05-02
US5821336A (en) 1998-10-13
GR3018521T3 (en) 1996-03-31
DD298948A5 (de) 1992-03-19
EP0412050A1 (de) 1991-02-06
GB8915414D0 (en) 1989-08-23
AU5809590A (en) 1991-01-10
DK0412050T3 (da) 1996-01-29
EP0412050B1 (de) 1995-12-20
ATE131873T1 (de) 1996-01-15
AU649226B2 (en) 1994-05-19
IE70519B1 (en) 1996-12-11
IE902426A1 (en) 1991-06-19
DE69024279D1 (de) 1996-02-01

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NOVARTIS AG, BASEL, CH

8339 Ceased/non-payment of the annual fee