DE68922971D1 - Mit einem Protein mit spezifischer Bindungsaktivität fusioniertes Aequorin, seine Herstellung, Reinigung und Nachweismethode. - Google Patents
Mit einem Protein mit spezifischer Bindungsaktivität fusioniertes Aequorin, seine Herstellung, Reinigung und Nachweismethode.Info
- Publication number
- DE68922971D1 DE68922971D1 DE68922971T DE68922971T DE68922971D1 DE 68922971 D1 DE68922971 D1 DE 68922971D1 DE 68922971 T DE68922971 T DE 68922971T DE 68922971 T DE68922971 T DE 68922971T DE 68922971 D1 DE68922971 D1 DE 68922971D1
- Authority
- DE
- Germany
- Prior art keywords
- purification
- protein
- production
- detection method
- specific binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/705—Fusion polypeptide containing domain for protein-protein interaction containing a protein-A fusion
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP30842488A JPH02154688A (ja) | 1988-12-06 | 1988-12-06 | 特異的結合能を有するタンパク質と融合したエクオリン及びその製造法 |
JP6986289A JPH02250900A (ja) | 1989-03-22 | 1989-03-22 | エクオリン標識した特異的結合タンパク質の精製法 |
JP7474289A JPH02253162A (ja) | 1989-03-27 | 1989-03-27 | 特異的結合能を有する物質と結合したエクオリンを用いる検出法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68922971D1 true DE68922971D1 (de) | 1995-07-13 |
DE68922971T2 DE68922971T2 (de) | 1995-10-19 |
Family
ID=27300161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1989622971 Expired - Fee Related DE68922971T2 (de) | 1988-12-06 | 1989-11-27 | Mit einem Protein mit spezifischer Bindungsaktivität fusioniertes Aequorin, seine Herstellung, Reinigung und Nachweismethode. |
Country Status (2)
Country | Link |
---|---|
EP (1) | EP0372352B1 (de) |
DE (1) | DE68922971T2 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2648713B1 (fr) * | 1989-06-26 | 1994-06-10 | Commissariat Energie Atomique | Proteines hybrides entre une enzyme extracytoplasmique et une autre proteine, leur procede de preparation, ainsi que leur application comme agent de diagnostic |
US5876935A (en) * | 1997-01-08 | 1999-03-02 | Dade Behring Inc. | Luminescent specific binding assay |
US6248542B1 (en) | 1997-12-09 | 2001-06-19 | Massachusetts Institute Of Technology | Optoelectronic sensor |
FR2778408A1 (fr) * | 1998-05-11 | 1999-11-12 | Univ Pasteur | Anticorps recombinants fluorescents |
WO2000002045A2 (en) † | 1998-07-06 | 2000-01-13 | Euroscreen S.A. | Bioluminescent assay for agonists or antagonists of a calcium-coupled receptor |
US8216797B2 (en) | 2001-02-07 | 2012-07-10 | Massachusetts Institute Of Technology | Pathogen detection biosensor |
MXPA03007070A (es) | 2001-02-07 | 2004-10-15 | Massachusetts Inst Technology | Sistema de deteccion optoelectronico. |
US7422860B2 (en) | 2001-02-07 | 2008-09-09 | Massachusetts Institute Of Technology | Optoelectronic detection system |
US20070259336A1 (en) * | 2004-12-23 | 2007-11-08 | Georgetown University | Methods for the detection of analytes in a sample |
JP2008048607A (ja) | 2006-08-22 | 2008-03-06 | Chisso Corp | Fc結合ドメインとカルシウム結合発光蛋白質との融合蛋白質、それをコードする遺伝子およびそれらの用途 |
GB2442118B (en) | 2006-09-19 | 2011-08-17 | Chisso Corp | Process for production of recombinant proteins as a soluble form |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3314812A1 (de) * | 1983-04-23 | 1984-10-25 | Battelle-Institut E.V., 6000 Frankfurt | Mittel zum antigen/antikoerper-nachweis |
DE3410437A1 (de) * | 1984-03-22 | 1985-09-26 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung von proteinen |
WO1987003304A1 (en) * | 1985-12-02 | 1987-06-04 | The Regents Of The University Of California | Isolation of dna sequences encoding luciferase activity and applications of the same |
JPS62261942A (ja) * | 1986-05-08 | 1987-11-14 | Chisso Corp | 金属の検出方法 |
JPS6439990A (en) * | 1987-08-05 | 1989-02-10 | Chisso Corp | Fused gene by bonding aequorin gene to functional gene |
-
1989
- 1989-11-27 DE DE1989622971 patent/DE68922971T2/de not_active Expired - Fee Related
- 1989-11-27 EP EP19890121881 patent/EP0372352B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE68922971T2 (de) | 1995-10-19 |
EP0372352A2 (de) | 1990-06-13 |
EP0372352B1 (de) | 1995-06-07 |
EP0372352A3 (en) | 1990-09-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |