DE68921974D1 - Bioreaktor. - Google Patents
Bioreaktor.Info
- Publication number
- DE68921974D1 DE68921974D1 DE68921974T DE68921974T DE68921974D1 DE 68921974 D1 DE68921974 D1 DE 68921974D1 DE 68921974 T DE68921974 T DE 68921974T DE 68921974 T DE68921974 T DE 68921974T DE 68921974 D1 DE68921974 D1 DE 68921974D1
- Authority
- DE
- Germany
- Prior art keywords
- bioreactor
- biocompatible
- chambers
- cell chamber
- cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/04—Tissue, human, animal or plant cell, or virus culture apparatus with means providing thin layers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M1/00—Apparatus for enzymology or microbiology
- C12M1/14—Apparatus for enzymology or microbiology with means providing thin layers or with multi-level trays
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/14—Scaffolds; Matrices
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/30—Synthetic polymers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/50—Proteins
- C12N2533/54—Collagen; Gelatin
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Transplantation (AREA)
- Cell Biology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Clinical Laboratory Science (AREA)
- Cardiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19770088A | 1988-05-23 | 1988-05-23 | |
US35511589A | 1989-05-18 | 1989-05-18 | |
PCT/US1989/002228 WO1989011529A1 (en) | 1988-05-23 | 1989-05-19 | Bioreactor device |
Publications (2)
Publication Number | Publication Date |
---|---|
DE68921974D1 true DE68921974D1 (de) | 1995-05-04 |
DE68921974T2 DE68921974T2 (de) | 1995-08-03 |
Family
ID=26893073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68921974T Expired - Fee Related DE68921974T2 (de) | 1988-05-23 | 1989-05-19 | Bioreaktor. |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0380610B1 (de) |
KR (1) | KR0131822B1 (de) |
AT (1) | ATE120485T1 (de) |
DE (1) | DE68921974T2 (de) |
WO (1) | WO1989011529A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5595909A (en) * | 1988-05-23 | 1997-01-21 | Regents Of The University Of Minnesota | Filter device |
US5605835A (en) * | 1988-05-23 | 1997-02-25 | Regents Of The University Of Minnesota | Bioreactor device with application as a bioartificial liver |
US5330915A (en) * | 1991-10-18 | 1994-07-19 | Endotronics, Inc. | Pressure control system for a bioreactor |
DE4206585C2 (de) * | 1992-03-03 | 1994-11-24 | Augustinus Dr Med Bader | Vorrichtung zur Massenkultur von Zellen |
US5728581A (en) * | 1995-06-07 | 1998-03-17 | Systemix, Inc. | Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein |
US5585266A (en) * | 1995-10-05 | 1996-12-17 | Plitt; Cheryl A. | Immobilized cell bioreactor |
DE19711114A1 (de) * | 1997-03-05 | 1998-09-17 | Uwe Dr Marx | Kultursystem Mikrokapillare |
US5955353A (en) * | 1997-05-22 | 1999-09-21 | Excorp Medical, Inc. | Hollow fiber bioreactor with an extrafilament flow plug |
DE59910847D1 (de) * | 1998-07-26 | 2004-11-18 | Klaus Rennebeck | Harnstofferzeugender organersatz |
US6372494B1 (en) | 1999-05-14 | 2002-04-16 | Advanced Tissue Sciences, Inc. | Methods of making conditioned cell culture medium compositions |
EP2118263A2 (de) * | 2007-03-14 | 2009-11-18 | CaridianBCT, Inc. | Zellexpansionsgerät mit plattenbioreaktor |
DE102008056413B4 (de) * | 2008-11-07 | 2014-12-24 | Bioregeneration Gmbh | Verfahren zur Herstellung eines Cellulose enthaltenden Körpers |
CN105002126B (zh) * | 2015-08-20 | 2017-12-29 | 福建出入境检验检疫局检验检疫技术中心 | 一种兼性需氧菌的简易批量培养方法 |
US11549090B2 (en) | 2016-08-21 | 2023-01-10 | Adva Biotechnology Ltd. | Bioreactor and methods of use thereof |
CN109984732A (zh) * | 2019-04-23 | 2019-07-09 | 广东省人民医院(广东省医学科学院) | 一套半体内动物实验血液相容性检测系统及其应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB178447A (en) * | 1921-04-12 | 1923-07-12 | Marquis Raul Pateras Pescara | Improvements in helicopters |
FR565349A (fr) * | 1923-04-23 | 1924-01-24 | Gazogène au bois avec dispositifs d'épuration sans eau | |
US3186917A (en) * | 1962-04-18 | 1965-06-01 | Biochemical Processes Inc | Process and apparatus for dialysis fermentation |
US3734851A (en) * | 1969-12-29 | 1973-05-22 | K Matsumura | Method and device for purifying blood |
CH593339A5 (de) * | 1973-07-02 | 1977-11-30 | Monsanto Co | |
DE2726313C3 (de) * | 1977-06-10 | 1980-02-07 | Battelle-Institut E.V., 6000 Frankfurt | Verfahren zur in-vitro-Biosynthese von Hormonen, insbesondere von Insulin |
US4184922A (en) * | 1977-11-11 | 1980-01-22 | The Government Of The United States | Dual circuit, woven artificial capillary bundle for cell culture |
US4220725A (en) * | 1978-04-03 | 1980-09-02 | United States Of America | Capillary cell culture device |
US4537860A (en) * | 1982-12-08 | 1985-08-27 | Monsanto Company | Static cell culture maintenance system |
US4661458A (en) * | 1983-08-31 | 1987-04-28 | Cell Environmental Systems, Ltd. | Cell culture system |
US4764471A (en) * | 1984-01-04 | 1988-08-16 | Nabisco Brands, Inc. | Continuous bioreactor and process |
DE3409501A1 (de) * | 1984-03-15 | 1985-10-24 | Sandoz-Patent-GmbH, 7850 Lörrach | Verfahren zur kultivierung von zellen |
US4603109A (en) * | 1984-06-01 | 1986-07-29 | Norton Company | Method and apparatus for contacting reactants in chemical and biological reactions |
IL75554A (en) * | 1985-06-18 | 1993-01-14 | Yeda Res & Dev | Matrix for cell cultivation in vitro |
DE3884801D1 (de) * | 1987-06-30 | 1993-11-11 | Brunswick Corp | Zellzuchtreaktor mit drei kammern, die von hydrophoben und hydrophilen membranen begrenzt sind. |
JPH0292270A (ja) * | 1988-09-30 | 1990-04-03 | Terumo Corp | 細胞培養装置 |
-
1989
- 1989-05-19 AT AT89907444T patent/ATE120485T1/de not_active IP Right Cessation
- 1989-05-19 DE DE68921974T patent/DE68921974T2/de not_active Expired - Fee Related
- 1989-05-19 EP EP89907444A patent/EP0380610B1/de not_active Expired - Lifetime
- 1989-05-19 WO PCT/US1989/002228 patent/WO1989011529A1/en active IP Right Grant
- 1989-05-19 KR KR1019900700116A patent/KR0131822B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
KR920700282A (ko) | 1992-02-19 |
EP0380610B1 (de) | 1995-03-29 |
EP0380610A4 (en) | 1991-12-18 |
WO1989011529A1 (en) | 1989-11-30 |
DE68921974T2 (de) | 1995-08-03 |
EP0380610A1 (de) | 1990-08-08 |
ATE120485T1 (de) | 1995-04-15 |
KR0131822B1 (ko) | 1998-04-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |