DE68911297D1 - Heparin bindende proteine, dafür kodierende dna, verfahren zu ihrer herstellung sowie sie enthaltende therapeutische präparate. - Google Patents

Heparin bindende proteine, dafür kodierende dna, verfahren zu ihrer herstellung sowie sie enthaltende therapeutische präparate.

Info

Publication number
DE68911297D1
DE68911297D1 DE89904014T DE68911297T DE68911297D1 DE 68911297 D1 DE68911297 D1 DE 68911297D1 DE 89904014 T DE89904014 T DE 89904014T DE 68911297 T DE68911297 T DE 68911297T DE 68911297 D1 DE68911297 D1 DE 68911297D1
Authority
DE
Germany
Prior art keywords
heparin
production
binding proteins
preparations containing
coding dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE89904014T
Other languages
English (en)
Other versions
DE68911297T2 (de
Inventor
Hans Flodgaard
Erik Ostergaard
Johannes Thomsen
Stephen Bayne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LEUKOTECH A/S, COPENHAGEN, DK
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK145388A external-priority patent/DK145388D0/da
Priority claimed from DK73789A external-priority patent/DK73789D0/da
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of DE68911297D1 publication Critical patent/DE68911297D1/de
Publication of DE68911297T2 publication Critical patent/DE68911297T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE89904014T 1988-03-17 1989-03-17 Heparin bindende proteine, dafür kodierende dna, verfahren zu ihrer herstellung sowie sie enthaltende therapeutische präparate. Expired - Fee Related DE68911297T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK145388A DK145388D0 (da) 1988-03-17 1988-03-17 Heparin-bindende protein
DK73789A DK73789D0 (da) 1989-02-17 1989-02-17 Heparin-bindende protein
PCT/DK1989/000059 WO1989008666A1 (en) 1988-03-17 1989-03-17 Heparin-binding proteins, dna cuding for them, processes for producing them as well as therapeutic preparations containing them

Publications (2)

Publication Number Publication Date
DE68911297D1 true DE68911297D1 (de) 1994-01-20
DE68911297T2 DE68911297T2 (de) 1994-03-31

Family

ID=26064553

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89904014T Expired - Fee Related DE68911297T2 (de) 1988-03-17 1989-03-17 Heparin bindende proteine, dafür kodierende dna, verfahren zu ihrer herstellung sowie sie enthaltende therapeutische präparate.

Country Status (12)

Country Link
EP (1) EP0409858B1 (de)
JP (1) JP2846385B2 (de)
AU (1) AU617795B2 (de)
DE (1) DE68911297T2 (de)
ES (1) ES2017122A6 (de)
FI (1) FI101626B1 (de)
HU (1) HU219883B (de)
IE (1) IE61947B1 (de)
IL (1) IL89661A (de)
NO (1) NO179588C (de)
NZ (2) NZ228370A (de)
WO (1) WO1989008666A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL92816A0 (en) * 1988-12-22 1990-09-17 Biogrowth Inc Recombinant dna molecules,hosts,processes and human somatomedin carrier protein-like polypeptides
RU2250213C2 (ru) 1989-01-31 2005-04-20 Джеффри С. РУБИН Выделенный белок фактора роста кератиноцита (kgf), рекомбинантная молекула днк, вектор, способ конструирования клетки-хозяина, способ получения белка, фармацевтическая композиция
US7026291B1 (en) 1989-01-31 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
US5198423A (en) * 1989-05-26 1993-03-30 Takara Shuzo Co., Ltd. Functional polypeptide containing a cell binding domain and a heparin binding domain of fibronectin
US5607916A (en) * 1989-07-05 1997-03-04 The Board Of Regents Of The University Of Oklahoma Method and composition for the treatment of septic shock
WO1992006705A1 (en) * 1990-10-16 1992-04-30 The Children's Medical Center Corporation Heparin binding mitogen with homology to epidermal growth factor (egf)
DK261490D0 (da) * 1990-10-31 1990-10-31 Novo Nordisk As New pharmaceutical compound
AU2658092A (en) * 1991-09-12 1993-04-05 Novo Nordisk A/S A method of screening for inhibitors of heparin-binding protein
RU2200573C2 (ru) * 1994-04-21 2003-03-20 Леукотех А/С Связывающий гепарин белок для лечения сепсиса
AU716791B2 (en) * 1995-03-09 2000-03-09 Leukotech A/S A protein-lipid conjugate, consisting of heparin binding protein (HBP) and a ceramide analogue, and its pharmaceutical use in treatment of conditions involving stress injury to cells
US5939390A (en) * 1995-03-09 1999-08-17 Novo Nordisk A/S Pharmaceutical composition
AU6670198A (en) * 1997-02-28 1998-09-18 The Texas A & M University System Heparan sulfate/heparin interacting protein compositions and methods of use
IL146128A0 (en) * 1999-04-29 2002-07-25 Leukotech As Expression of heparin-binding protein in recombinant mammalian cells
AU2003226907A1 (en) * 2002-03-27 2003-10-08 Leukotech A/S Method for the preparation of recombinant mammalian heparin-binding protein (hbp)
WO2006036002A1 (ja) * 2004-09-28 2006-04-06 Kurume University 新規骨転移マーカーペプチドおよびそれを用いた骨転移の診断方法
CN112647358A (zh) * 2020-12-07 2021-04-13 静宁县恒达有限责任公司 一种磷硼杂链预聚物嵌段聚氨酯水性防潮阻燃纸箱覆膜剂及其制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0241136A3 (de) * 1986-03-07 1989-12-27 The President And Fellows Of Harvard College Humaner, Klasse 1 Heparin bindender, Wachstumsfaktor
US4883751A (en) * 1986-05-28 1989-11-28 New York University Specific immunoassay for heparin
EP0364481A4 (en) * 1987-06-18 1992-01-22 Monash University Growth factors
EP0377579A1 (de) * 1987-07-07 1990-07-18 California Biotechnology, Inc. Rekombinante fibroblasten-wachstumsfaktoren

Also Published As

Publication number Publication date
NZ243844A (en) 1994-01-26
AU617795B2 (en) 1991-12-05
FI101626B (fi) 1998-07-31
IL89661A0 (en) 1989-09-28
EP0409858A1 (de) 1991-01-30
FI904546A0 (fi) 1990-09-14
IE890864L (en) 1989-09-17
NO904024L (no) 1990-11-13
AU3346289A (en) 1989-10-05
HU219883B (hu) 2001-08-28
IL89661A (en) 1999-05-09
NO179588C (no) 1996-11-06
FI101626B1 (fi) 1998-07-31
NO904024D0 (no) 1990-09-14
HUT58107A (en) 1992-01-28
HU892118D0 (en) 1991-05-28
ES2017122A6 (es) 1991-01-01
IE61947B1 (en) 1994-11-30
JP2846385B2 (ja) 1999-01-13
EP0409858B1 (de) 1993-12-08
NZ228370A (en) 1994-01-26
JPH03504919A (ja) 1991-10-31
DE68911297T2 (de) 1994-03-31
WO1989008666A1 (en) 1989-09-21
NO179588B (no) 1996-07-29

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: LEUKOTECH A/S, COPENHAGEN, DK

8339 Ceased/non-payment of the annual fee