DE68907687D1 - In einer zur erhoehung ihrer loeslichkeitsrate geeigneten form auf polymere substanzen aufgebrachte schwerloesliche arzneistoffe. - Google Patents

In einer zur erhoehung ihrer loeslichkeitsrate geeigneten form auf polymere substanzen aufgebrachte schwerloesliche arzneistoffe.

Info

Publication number
DE68907687D1
DE68907687D1 DE8989119241T DE68907687T DE68907687D1 DE 68907687 D1 DE68907687 D1 DE 68907687D1 DE 8989119241 T DE8989119241 T DE 8989119241T DE 68907687 T DE68907687 T DE 68907687T DE 68907687 D1 DE68907687 D1 DE 68907687D1
Authority
DE
Germany
Prior art keywords
substances
heavy
increase
polymers
medicament
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8989119241T
Other languages
English (en)
Other versions
DE68907687T2 (de
Inventor
Mara Lucia Lovrecich
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adare Pharmaceuticals SRL
Original Assignee
Vectorpharma International SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vectorpharma International SpA filed Critical Vectorpharma International SpA
Publication of DE68907687D1 publication Critical patent/DE68907687D1/de
Application granted granted Critical
Publication of DE68907687T2 publication Critical patent/DE68907687T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE89119241T 1988-10-17 1989-10-17 In einer zur Erhöhung ihrer Löslichkeitsrate geeigneten Form auf polymere Substanzen aufgebrachte schwerlösliche Arzneistoffe. Expired - Lifetime DE68907687T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8822336A IT1230566B (it) 1988-10-17 1988-10-17 Farmaci poco solubili supportati su sostanze polimeriche in forma atta all'aumento della velocita' di dissoluzione

Publications (2)

Publication Number Publication Date
DE68907687D1 true DE68907687D1 (de) 1993-08-26
DE68907687T2 DE68907687T2 (de) 1993-10-28

Family

ID=11194858

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89119241T Expired - Lifetime DE68907687T2 (de) 1988-10-17 1989-10-17 In einer zur Erhöhung ihrer Löslichkeitsrate geeigneten Form auf polymere Substanzen aufgebrachte schwerlösliche Arzneistoffe.

Country Status (10)

Country Link
EP (1) EP0364944B1 (de)
JP (1) JP2869103B2 (de)
KR (1) KR0148006B1 (de)
AT (1) ATE91622T1 (de)
CA (1) CA2000744C (de)
DE (1) DE68907687T2 (de)
ES (1) ES2060715T3 (de)
HU (1) HU203481B (de)
IT (1) IT1230566B (de)
YU (1) YU198489A (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1243745B (it) * 1990-10-17 1994-06-21 Vectorpharma Int Composizioni terapeutiche transdermali contenenti farmaco e/o agente promotore dell'assorbimento cutaneo supportato su particelle microporose e microsfere polimeriche e loro preparazione.
EP1004318A3 (de) * 1991-06-21 2002-08-07 Takeda Chemical Industries, Ltd. Zyklodextrin-zusammensetzung
IT1252867B (it) * 1991-12-31 1995-06-28 Gentili Ist Spa Composizioni farmaceutiche contenenti progesterone ad elevata biodisponibilita'
AU722246B2 (en) * 1995-06-07 2000-07-27 Johnson & Johnson Consumer Products, Inc. Stable complexes of crosslinked polyvinylpyrrolidone and iodine and method of making the same
NL1003503C2 (nl) * 1996-07-04 1998-01-07 Negma Steba International Dev Farmaceutische samenstelling voor orale toediening.
US6287693B1 (en) 1998-02-25 2001-09-11 John Claude Savoir Stable shaped particles of crystalline organic compounds
AU2162700A (en) * 1998-12-04 2000-06-26 California Institute Of Technology Supramolecular complexes containing therapeutic agents
IT1318404B1 (it) * 2000-03-17 2003-08-25 Eurand Int Processo per la preparazione di formulazioni a rilascio accelerato conimpiego di fluidi compressi.
EP2277551B1 (de) 2002-09-06 2013-05-08 Cerulean Pharma Inc. Polymere auf basis von cyclodextrin zur verabreichung von an diese kovalent gebundene arzneimittel
ES2537551T3 (es) 2003-06-13 2015-06-09 Skendi Finance, Ltd. Formulación de estradiol-progesterona de liberación lenta
DE102006026578B4 (de) 2006-06-08 2009-01-08 Lts Lohmann Therapie-Systeme Ag Wirkstoffpartikelhaltiges Transdermales Therapeutisches System mit erhöhtem Wirkstofffluss und Verfahren zu seiner Herstellung sowie Verwendung
JP2010516625A (ja) 2007-01-24 2010-05-20 インサート セラピューティクス， インコーポレイテッド 制御された薬物送達のためのテザー基を有するポリマー−薬物コンジュゲート
EP3207921A1 (de) 2007-09-14 2017-08-23 Wockhardt Limited Rhein- oder diacereinzusammensetzungen
GB0812742D0 (en) 2008-07-11 2008-08-20 Critical Pharmaceuticals Ltd Process
TWI473610B (zh) * 2008-10-28 2015-02-21 Twi Biotechnology Inc 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物
IE20100799A1 (en) 2010-12-22 2012-08-01 Eurand Pharmaceuticals Ltd Pharmaceutical composites of poorly water soluble drugs and polymers
WO2014055493A1 (en) 2012-10-02 2014-04-10 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU189534B (en) 1981-09-09 1986-07-28 Chinoin Rt.,Hu Process for producing new tablets containing cyclodextrin polymer as desintegrator
DE3326167A1 (de) * 1983-07-20 1985-02-21 Dr. Rentschler Arzneimittel Gmbh & Co, 7958 Laupheim Feste arzneiformen, die als wirkstoff n-4-(2-(5-chlor-2-methoxybenzamido)-ethyl)-phenylsulfonyl-n'-cyclohexylharnstoff enthalten und verfahren zu ihrer herstellung
IE63321B1 (en) * 1986-02-03 1995-04-05 Elan Corp Plc Drug delivery system

Also Published As

Publication number Publication date
CA2000744C (en) 1999-12-07
HU203481B (en) 1991-08-28
KR900005960A (ko) 1990-05-07
IT1230566B (it) 1991-10-28
IT8822336A0 (it) 1988-10-17
ATE91622T1 (de) 1993-08-15
HUT52398A (en) 1990-07-28
JP2869103B2 (ja) 1999-03-10
EP0364944A1 (de) 1990-04-25
CA2000744A1 (en) 1990-04-17
YU198489A (en) 1991-08-31
KR0148006B1 (ko) 1998-08-17
ES2060715T3 (es) 1994-12-01
EP0364944B1 (de) 1993-07-21
DE68907687T2 (de) 1993-10-28
JPH02149513A (ja) 1990-06-08
HU895330D0 (en) 1990-01-28

Similar Documents

Publication Publication Date Title
DE68907687D1 (de) In einer zur erhoehung ihrer loeslichkeitsrate geeigneten form auf polymere substanzen aufgebrachte schwerloesliche arzneistoffe.
KR880000106A (ko) 지속적으로 방출하는 제약학적 제제
ES8604020A1 (es) Un procedimiento para la obtencion de polimeros porosos reticulados para liberacion controlada de farmacos
DE3587269D1 (de) Pfropfcopolymerisate aus vernetzten polymeren und polyoxyethylen, verfahren zu ihrer herstellung und ihre verwendung.
IT1241417B (it) Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione
ATE29220T1 (de) Verfahren zur herstellung von unloeslichen, nur wenig quellbaren polymerisaten von basischen vinylheterocyclen und deren verwendung.
DK243886D0 (da) Middel til styret frigoerelse af et makromolekylaert medikament og fremgangsmaade til fremstilling af midlet
ES2052573T3 (es) Particulas polimericas, su fabricacion y utilizaciones.
MX168535B (es) Membrana de filtracion semipermeable, y no adsortiva
ES8301640A1 (es) Procedimiento para la preparacion de un producto para el tratamiento de heridas a base de un polimero organico hinchable
ATE114458T1 (de) Bioelastomeres arzneimittelabgabesystem.
JPS51148788A (en) A process for preparing hydrophilic polymers
ATE2624T1 (de) Verfahren zur herstellung wasserloeslicher acryl- polymere oder -copolymere mit hohem molekulargewicht und niedrigem gehalt an nicht umgesetzten monomeren.
JPS55106211A (en) Porous crosslinked copolymer of chloromethylstyrene and its iminodiacetic acid derivative, and preparation thereof
ES2105124T3 (es) Procedimiento de preparacion de polimeros reticulados que contienen grupos carboxilicos.
ATE304557T1 (de) Einführung von funktionellen gruppen an polymeren
SE8601563D0 (sv) Matrismaterial, forfarande for framstellning derav och anvendning derav
JPS5738823A (en) Ion-exchange membrane and its production
JPS55114306A (en) Treating agent for semipermeable membrane and its manufacturing method
JPS53118489A (en) Production of vinyl ester polymer
ATE72049T1 (de) Verfahren zur herstellung von polymerteilchen oder einem latex von polymerteilchen mit auf ihrer oberflaeche amphiphilen molekuelen mit ionogenen oder reaktionsfaehigen gruppen.
JPS545096A (en) Method of immobilizing enzyme or mold using betain polymer
JPS5266726A (en) Preparation of spinning dope
ES8800288A1 (es) Un procedimiento para preparar un hidrogel parcialmente neutralizado, ligeramente reticulado, sustancialmente insoluble en agua
JPS52105992A (en) Preparation of hydrophilic high polymers

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: EURAND INTERNATIONAL S.P.A., MAILAND/MILANO, IT

8328 Change in the person/name/address of the agent

Representative=s name: VONNEMANN, KLOIBER & KOLLEGEN, 80796 MUENCHEN