DE68904264T2 - Fragmente und fraktionen von heparin mit wirkung gegen hiv. - Google Patents

Fragmente und fraktionen von heparin mit wirkung gegen hiv.

Info

Publication number
DE68904264T2
DE68904264T2 DE8989202061T DE68904264T DE68904264T2 DE 68904264 T2 DE68904264 T2 DE 68904264T2 DE 8989202061 T DE8989202061 T DE 8989202061T DE 68904264 T DE68904264 T DE 68904264T DE 68904264 T2 DE68904264 T2 DE 68904264T2
Authority
DE
Germany
Prior art keywords
fractions
heparin
fragments
effect against
against hiv
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989202061T
Other languages
English (en)
Other versions
DE68904264D1 (de
Inventor
Henricus Carl Josep Ottenheijm
Hollander Franciscus Corne Den
Clercq Erik Desire Alice De
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Akzo Nobel NV
Original Assignee
Akzo NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo NV filed Critical Akzo NV
Application granted granted Critical
Publication of DE68904264D1 publication Critical patent/DE68904264D1/de
Publication of DE68904264T2 publication Critical patent/DE68904264T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078Degradation products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
DE8989202061T 1988-08-24 1989-08-09 Fragmente und fraktionen von heparin mit wirkung gegen hiv. Expired - Fee Related DE68904264T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8802087 1988-08-24

Publications (2)

Publication Number Publication Date
DE68904264D1 DE68904264D1 (de) 1993-02-18
DE68904264T2 true DE68904264T2 (de) 1993-05-27

Family

ID=19852794

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989202061T Expired - Fee Related DE68904264T2 (de) 1988-08-24 1989-08-09 Fragmente und fraktionen von heparin mit wirkung gegen hiv.

Country Status (13)

Country Link
EP (1) EP0355905B1 (de)
JP (1) JPH02108624A (de)
KR (1) KR0143084B1 (de)
AT (1) ATE84217T1 (de)
AU (1) AU617850B2 (de)
CA (1) CA1330305C (de)
DE (1) DE68904264T2 (de)
DK (1) DK416089A (de)
ES (1) ES2053953T3 (de)
IE (1) IE61565B1 (de)
NZ (1) NZ230394A (de)
PT (1) PT91524B (de)
ZA (1) ZA896231B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08109134A (ja) * 1994-10-11 1996-04-30 Sanwa Kagaku Kenkyusho Co Ltd 細胞変成抑制並びに臓器毒性軽減剤
US6001820A (en) * 1995-03-31 1999-12-14 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5744457A (en) * 1995-03-31 1998-04-28 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
GB2299998B (en) * 1995-03-31 1997-03-26 Hamilton Civic Hospitals Res Compositions for inhibiting thrombogenesis
US5763427A (en) * 1995-03-31 1998-06-09 Hamilton Civic Hospitals Research Development Inc. Compositions and methods for inhibiting thrombogenesis
US5767269A (en) * 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
DE19836339B4 (de) 1998-08-11 2011-12-22 N.V. Nutricia Kohlenhydratmischung
DE60127703D1 (de) * 2000-11-09 2007-05-16 Contrimmune Biotechnology Inc Verwendung von xestospongin c zur behandlung oder vorbeugung einer hiv-infektion
FR2838649B1 (fr) * 2002-04-19 2006-01-13 Commissariat Energie Atomique Composition anti-vih, procede de fabrication et medicament
US20040229778A1 (en) * 2003-05-13 2004-11-18 Elmaleh David R. Pharmaceutical compositions of antithrombin III for the treatment of retroviral diseases
EP1597978A1 (de) 2004-05-17 2005-11-23 Nutricia N.V. Synergie von GOS und polyfruktose
US8252769B2 (en) 2004-06-22 2012-08-28 N. V. Nutricia Intestinal barrier integrity
EP1721611A1 (de) * 2005-04-21 2006-11-15 N.V. Nutricia Nahrungsergänzungspräparat mit Oligosacchariden für eine Kategorie von HIV Patienten
WO2011002027A1 (ja) 2009-07-03 2011-01-06 テイ・エス テック株式会社 乗物用シート
RU2013113723A (ru) 2010-09-14 2014-10-20 Ф.Хоффманн-Ля Рош Аг Гибридный полипептид с серпиновым "пальцем"

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3422518A1 (de) * 1984-06-16 1985-12-19 B. Braun Melsungen Ag, 3508 Melsungen Heparin-derivate, verfahren zu ihrer herstellung, diese enthaltende arzneimittel und ihre verwendung bei der behandlung von fettstoffwechselstoerungen
ZA878877B (en) * 1986-11-29 1988-05-24 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Treatment of diseases caused by viruses
WO1990003791A1 (en) * 1988-10-05 1990-04-19 Nicola Diferrante Methods for interfering with hiv multiplication and composition for the treatment of aids

Also Published As

Publication number Publication date
PT91524B (pt) 1995-07-18
DK416089A (da) 1990-02-25
IE892565L (en) 1990-02-24
ZA896231B (en) 1990-05-30
DE68904264D1 (de) 1993-02-18
CA1330305C (en) 1994-06-21
DK416089D0 (da) 1989-08-23
ES2053953T3 (es) 1994-08-01
AU4001289A (en) 1990-03-01
KR900002788A (ko) 1990-03-23
ATE84217T1 (de) 1993-01-15
JPH02108624A (ja) 1990-04-20
PT91524A (pt) 1990-03-08
AU617850B2 (en) 1991-12-05
KR0143084B1 (ko) 1998-07-15
EP0355905A1 (de) 1990-02-28
EP0355905B1 (de) 1993-01-07
NZ230394A (en) 1997-02-24
IE61565B1 (en) 1994-11-16

Similar Documents

Publication Publication Date Title
DE68904264T2 (de) Fragmente und fraktionen von heparin mit wirkung gegen hiv.
ATE264914T1 (de) Antivirale proteine, dafür kodierende dna, und deren verwendung
PT94247A (pt) Processo para a preparacao de uma composicao farmaceutica contendo 3'-azido-3'-desoxitimidina e n-butil-desoxinojirimicina e metodo para inibir hiv utilizando-a
DE69233760D1 (de) Inhibitoren der menschlichen Elastase von Neutrophilen
PT88930A (pt) Processo para a preparacao de novos analogos de nucleosidos e de composicoes farmaceuticas que os contem
SE9602931L (sv) Ny medicinsk användning
EE9400183A (et) Inimese immuunpuudulikkuse viiruse vaktsiin ja kasutamine
ATE81980T1 (de) Pharmazeutisches kombinationspraeparat sowie dessen herstellung und verwendung.
ES2063796T3 (es) Nuevos derivados de 2'-halometiliden, 2'-eteniliden- y 2'-etinil-adenosina.
DE69023708D1 (de) Anti-hiv-heilmittel.
DE69403063T2 (de) Gegen viren wirksame naphtochinon-verbindungen, zusammensetzungen und deren verwendungen
IT8823121A0 (it) Derivati della 1,2,5,6-tetraidropiridina, loro procedimento di preparazione e loro impiego come sostanze medicinali
IL88731A0 (en) Non-reverting rna viruses
EP0311107A3 (de) Anti-HIV-aktive 3'-Fluoro-purin-2',3'-dideoxyriboside
PT89266A (pt) Metodo para a inibicao de virus da imunodeficiencia humana utilizando um derivado n-n-butilo de desoxinojirimicina
DE68914990D1 (de) Verfahren zur inhibierung der wirkung des menschlichen immunschwäche-virus (hiv) in vivo.
AU2880595A (en) Use of pharmaceutical agents for restoring, alleviation, or treatment of immunodeficiency, including the alleviation or treatment of the immune dysfunction related to infection with human immunodeficiency viruses (hiv) or related viruses
ATE58478T1 (de) Zubereitungen und verfahren zum schutz von tlymphozyten gegen das krankheitsagens von lymphadenopathie und vom erworbenen immundepressionsyndrom.
WO1990005523A3 (en) Phenanthrolinedicarboxylate esters, 4-aminoquinoline and isoquinoline derivatives as inhibitors of hiv reverse transcriptase
ES2066897T3 (es) 5,11-dihidro-6h-pirido(2,3-b)(1,4)benzodiazepin-6-onas y -tionas y su uso en la prevencion o el tratamiento del sida.
EP0305777A3 (de) Herstellung von Antigenen des Human Immunodeficiency Virus Typ 1 sowie deren Verwendung als diagnostisches Mittel und Therapeutikum
ATE64855T1 (de) Zubereitungen und verfahren zum schutz von tlymphozyten gegen das krankheitsagens von lymphadenopathie und vom erworbenen immundepressionsyndrom.
DE68907971D1 (de) Verwendung von spergualin-derivaten gegen nebenwirkungen radiologischen oder medikamentoesen ursprungs.
AU3713489A (en) Non-reverting rna viruses
NO891717D0 (no) Ekspresjon av hiv 24 kda gag-protein i metylotrofe gjaersorter.

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AKZO NOBEL N.V., ARNHEIM/ARNHEM, NL

8339 Ceased/non-payment of the annual fee