DE60332714D1 - Enzymatische racematspaltung von propylenglykol-alkyl (oder aryl-)-ethern und ether acetaten - Google Patents
Enzymatische racematspaltung von propylenglykol-alkyl (oder aryl-)-ethern und ether acetatenInfo
- Publication number
- DE60332714D1 DE60332714D1 DE60332714T DE60332714T DE60332714D1 DE 60332714 D1 DE60332714 D1 DE 60332714D1 DE 60332714 T DE60332714 T DE 60332714T DE 60332714 T DE60332714 T DE 60332714T DE 60332714 D1 DE60332714 D1 DE 60332714D1
- Authority
- DE
- Germany
- Prior art keywords
- aryl
- ethers
- propylene glycol
- ether acetates
- glycol alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 title abstract 7
- 150000002170 ethers Chemical class 0.000 title abstract 2
- 230000002255 enzymatic effect Effects 0.000 title 1
- IPBVNPXQWQGGJP-UHFFFAOYSA-N phenyl acetate Chemical compound CC(=O)OC1=CC=CC=C1 IPBVNPXQWQGGJP-UHFFFAOYSA-N 0.000 title 1
- 102000004157 Hydrolases Human genes 0.000 abstract 4
- 108090000604 Hydrolases Proteins 0.000 abstract 4
- -1 Glycol ether acetates Chemical class 0.000 abstract 3
- 239000004367 Lipase Substances 0.000 abstract 2
- 102000004882 Lipase Human genes 0.000 abstract 2
- 108090001060 Lipase Proteins 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 235000019421 lipase Nutrition 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 125000002252 acyl group Chemical group 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 abstract 1
- 238000005809 transesterification reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/18—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36676702P | 2002-03-22 | 2002-03-22 | |
| PCT/US2003/008941 WO2003083126A2 (en) | 2002-03-22 | 2003-03-21 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60332714D1 true DE60332714D1 (de) | 2010-07-08 |
Family
ID=28675281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60332714T Expired - Lifetime DE60332714D1 (de) | 2002-03-22 | 2003-03-21 | Enzymatische racematspaltung von propylenglykol-alkyl (oder aryl-)-ethern und ether acetaten |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7264960B2 (https=) |
| EP (1) | EP1490501B1 (https=) |
| JP (1) | JP2005520570A (https=) |
| KR (1) | KR20040099348A (https=) |
| CN (1) | CN1656230B (https=) |
| AT (1) | ATE469237T1 (https=) |
| AU (1) | AU2003222053A1 (https=) |
| DE (1) | DE60332714D1 (https=) |
| WO (1) | WO2003083126A2 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005095629A1 (en) * | 2004-03-29 | 2005-10-13 | Dsm Ip Assets B.V. | Process for the preparation of enantiomerically enriched esters and alcohols by means of azeotropically dried enzyme compositions |
| US7570651B2 (en) * | 2004-06-16 | 2009-08-04 | Siamack Haghighi | High-performance reconfigurable interconnect for concurrent operation of multiple systems |
| KR100650798B1 (ko) * | 2004-07-19 | 2006-11-27 | (주)제이코통상 | 광학활성 카복실산의 제조방법 |
| KR100650797B1 (ko) * | 2005-12-12 | 2006-11-27 | (주)케미코월드 | 광학활성 사이클로프로판 카복사미드의 제조방법 |
| CN100427608C (zh) * | 2006-11-08 | 2008-10-22 | 浙江大学 | 酶法拆分制备光学活性烯丙基呋喃甲醇的方法 |
| EP2655646A4 (en) * | 2010-12-20 | 2014-05-21 | Du Pont | TARGETED PERHYDROLASES |
| DE102011107959A1 (de) * | 2011-07-20 | 2013-01-24 | Thyssenkrupp Uhde Gmbh | Herstellung von optisch reinem Propan-1,2-diol |
| CN114058655B (zh) * | 2021-11-30 | 2023-08-29 | 青岛科技大学 | 一种酶-化学一锅法合成(r)-乙酰胺基苯丙醇的方法 |
| CN119585437A (zh) * | 2022-07-29 | 2025-03-07 | 上海皓元医药股份有限公司 | 一种艾日布林中间体的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5541080A (en) | 1991-11-01 | 1996-07-30 | Wisconsin Alumni Research Fdn. | Method for preparing L-alpha-amino acids |
| JP3874035B2 (ja) * | 1996-06-26 | 2007-01-31 | 三菱瓦斯化学株式会社 | 光学活性２級アルコールの製造法 |
| JP2000063312A (ja) * | 1998-08-17 | 2000-02-29 | Mitsubishi Gas Chem Co Inc | 光学活性２級アルコール及びその製造法 |
-
2003
- 2003-03-21 AU AU2003222053A patent/AU2003222053A1/en not_active Abandoned
- 2003-03-21 JP JP2003580559A patent/JP2005520570A/ja active Pending
- 2003-03-21 US US10/502,692 patent/US7264960B2/en not_active Expired - Fee Related
- 2003-03-21 DE DE60332714T patent/DE60332714D1/de not_active Expired - Lifetime
- 2003-03-21 CN CN038067668A patent/CN1656230B/zh not_active Expired - Fee Related
- 2003-03-21 WO PCT/US2003/008941 patent/WO2003083126A2/en not_active Ceased
- 2003-03-21 KR KR10-2004-7014868A patent/KR20040099348A/ko not_active Withdrawn
- 2003-03-21 AT AT03718037T patent/ATE469237T1/de not_active IP Right Cessation
- 2003-03-21 EP EP03718037A patent/EP1490501B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1490501A2 (en) | 2004-12-29 |
| CN1656230B (zh) | 2010-06-23 |
| AU2003222053A1 (en) | 2003-10-13 |
| WO2003083126A8 (en) | 2005-03-17 |
| ATE469237T1 (de) | 2010-06-15 |
| JP2005520570A (ja) | 2005-07-14 |
| WO2003083126A2 (en) | 2003-10-09 |
| US20050026260A1 (en) | 2005-02-03 |
| EP1490501B1 (en) | 2010-05-26 |
| US7264960B2 (en) | 2007-09-04 |
| WO2003083126A3 (en) | 2004-01-22 |
| KR20040099348A (ko) | 2004-11-26 |
| CN1656230A (zh) | 2005-08-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition |