DE60328035D1 - Neue azolderivate - Google Patents
Neue azolderivateInfo
- Publication number
- DE60328035D1 DE60328035D1 DE60328035T DE60328035T DE60328035D1 DE 60328035 D1 DE60328035 D1 DE 60328035D1 DE 60328035 T DE60328035 T DE 60328035T DE 60328035 T DE60328035 T DE 60328035T DE 60328035 D1 DE60328035 D1 DE 60328035D1
- Authority
- DE
- Germany
- Prior art keywords
- disorders
- methine
- diseases
- nitrogen
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical class C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title abstract 3
- 125000001434 methanylylidene group Chemical group [H]C#[*] 0.000 abstract 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- 208000018522 Gastrointestinal disease Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000003851 azoles Chemical class 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 210000004392 genitalia Anatomy 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 208000030159 metabolic disease Diseases 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 230000001850 reproductive effect Effects 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Addiction (AREA)
- Urology & Nephrology (AREA)
- Reproductive Health (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002346997 | 2002-11-29 | ||
PCT/JP2003/015018 WO2004050652A1 (ja) | 2002-11-29 | 2003-11-25 | 新規アゾール誘導体 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60328035D1 true DE60328035D1 (de) | 2009-07-30 |
Family
ID=32462868
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60328035T Expired - Lifetime DE60328035D1 (de) | 2002-11-29 | 2003-11-25 | Neue azolderivate |
Country Status (8)
Country | Link |
---|---|
US (2) | US7365079B2 (de) |
EP (1) | EP1566384B1 (de) |
JP (2) | JPWO2004050652A1 (de) |
AT (1) | ATE433971T1 (de) |
AU (1) | AU2003302640B2 (de) |
CA (1) | CA2507742A1 (de) |
DE (1) | DE60328035D1 (de) |
WO (1) | WO2004050652A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6374762B1 (en) * | 1997-10-27 | 2002-04-23 | Correct Craft, Inc. | Water sport towing apparatus |
US7105526B2 (en) * | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
CA2532505A1 (en) * | 2003-07-24 | 2005-02-10 | Pharmagene Laboratories Limited | 5-ht2b receptor antagonists |
WO2005030210A1 (en) * | 2003-09-26 | 2005-04-07 | Pfizer Products Inc. | Treatment of neurological disorders related to rapid eye movement (rem) sleep disturbances with npy y5 receptor antagonists |
US7803838B2 (en) * | 2004-06-04 | 2010-09-28 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
US7838552B2 (en) | 2004-06-04 | 2010-11-23 | Forest Laboratories Holdings Limited | Compositions comprising nebivolol |
JP2008510728A (ja) | 2004-08-19 | 2008-04-10 | バーテックス ファーマシューティカルズ インコーポレイテッド | ムスカリン受容体のモジュレーター |
US7786141B2 (en) | 2004-08-19 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Dihydrospiroindene modulators of muscarinic receptors |
WO2006028239A1 (ja) * | 2004-09-07 | 2006-03-16 | Banyu Pharmaceutical Co., Ltd. | カルバモイル置換スピロ誘導体 |
US7863449B2 (en) | 2004-11-29 | 2011-01-04 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
US20070035750A1 (en) * | 2005-08-10 | 2007-02-15 | Canon Kabushiki Kaisha | Configurable device model for n-channel device |
JP2009514858A (ja) * | 2005-11-03 | 2009-04-09 | メルク エンド カムパニー インコーポレーテッド | アリール−ピラゾリルモチーフを有するヒストンデアセチラーゼ阻害剤 |
US8158791B2 (en) | 2005-11-10 | 2012-04-17 | Msd K.K. | Aza-substituted spiro derivatives |
KR20080087841A (ko) * | 2005-12-22 | 2008-10-01 | 버텍스 파마슈티칼스 인코포레이티드 | 무스카린 수용체의 조절제 |
JP2009527569A (ja) * | 2006-02-22 | 2009-07-30 | バーテックス ファーマシューティカルズ インコーポレイテッド | ムスカリン受容体の調節剤 |
CA2643320A1 (en) * | 2006-02-22 | 2007-09-07 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
EP2040706A2 (de) * | 2006-06-29 | 2009-04-01 | Vertex Pharmceuticals Incorporated | Modulatoren muskarinischer rezeptoren |
WO2008021375A2 (en) * | 2006-08-15 | 2008-02-21 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
US7786107B2 (en) | 2006-08-18 | 2010-08-31 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
WO2008056687A1 (fr) * | 2006-11-09 | 2008-05-15 | Daiichi Sankyo Company, Limited | Nouveau dérivé de spiropipéridine |
US7973162B2 (en) * | 2007-10-03 | 2011-07-05 | Vertex Pharmaceuticals Incorporated | Modulators of muscarinic receptors |
US9168248B2 (en) * | 2009-02-17 | 2015-10-27 | Merck Canada Inc. | Spiro compounds useful as inhibitors of stearoyl-coenzyme A delta-9 desaturase |
JP5739674B2 (ja) | 2010-09-27 | 2015-06-24 | 任天堂株式会社 | 情報処理プログラム、情報処理装置、情報処理システム、および、情報処理方法 |
SI3083633T1 (en) * | 2013-12-19 | 2018-02-28 | F. Hoffmann-La Roche Ag | Spiro-oxazolones |
TW201600522A (zh) * | 2014-02-20 | 2016-01-01 | 赫孚孟拉羅股份公司 | 螺-唑酮 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69929235T2 (de) * | 1998-11-10 | 2006-08-24 | Merck & Co., Inc. | Spiro-indole als y5-rezeptor antagonisten |
JP3411262B2 (ja) * | 1999-08-20 | 2003-05-26 | 萬有製薬株式会社 | 新規スピロ化合物 |
TWI279402B (en) | 1999-08-20 | 2007-04-21 | Banyu Pharma Co Ltd | Spiro compounds having NPY antagonistic activities and agents containing the same |
DE60115092T2 (de) | 2000-12-12 | 2006-03-30 | Neurogen Corp., Brandford | Spiro[isobenzofuran-1,4'-piperidin]-3-one und 3h-spiroisobenzofuran-1,4'-piperidine |
US7105526B2 (en) * | 2002-06-28 | 2006-09-12 | Banyu Pharmaceuticals Co., Ltd. | Benzimidazole derivatives |
-
2003
- 2003-11-25 EP EP03812297A patent/EP1566384B1/de not_active Expired - Lifetime
- 2003-11-25 DE DE60328035T patent/DE60328035D1/de not_active Expired - Lifetime
- 2003-11-25 JP JP2004556840A patent/JPWO2004050652A1/ja active Pending
- 2003-11-25 CA CA002507742A patent/CA2507742A1/en not_active Abandoned
- 2003-11-25 US US10/536,360 patent/US7365079B2/en not_active Expired - Fee Related
- 2003-11-25 WO PCT/JP2003/015018 patent/WO2004050652A1/ja active Application Filing
- 2003-11-25 AU AU2003302640A patent/AU2003302640B2/en not_active Ceased
- 2003-11-25 AT AT03812297T patent/ATE433971T1/de not_active IP Right Cessation
-
2008
- 2008-02-26 US US12/071,808 patent/US7589096B2/en not_active Expired - Fee Related
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2010
- 2010-06-03 JP JP2010127480A patent/JP2010215654A/ja not_active Withdrawn
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AU2003302640A1 (en) | 2004-06-23 |
US7589096B2 (en) | 2009-09-15 |
US7365079B2 (en) | 2008-04-29 |
JP2010215654A (ja) | 2010-09-30 |
CA2507742A1 (en) | 2004-06-17 |
ATE433971T1 (de) | 2009-07-15 |
EP1566384A4 (de) | 2007-11-21 |
WO2004050652A1 (ja) | 2004-06-17 |
US20080188507A1 (en) | 2008-08-07 |
JPWO2004050652A1 (ja) | 2006-03-30 |
EP1566384A1 (de) | 2005-08-24 |
US20060111380A1 (en) | 2006-05-25 |
EP1566384B1 (de) | 2009-06-17 |
AU2003302640B2 (en) | 2009-09-24 |
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